Cell Stem Cell February 2023 PMID 36736289

Structural and functional integration of human forebrain organoids with the injured adult rat visual system.

Dennis Jgamadze, James T Lim, Zhijian Zhang, Paul M Harary, James Germi, Kobina Mensah-Brown, Christopher D Adam, Ehsan Mirzakhalili, Shikha Singh, Jiahe Ben Gu, Rachel Blue, Mehek Dedhia, Marissa Fu, Fadi Jacob, Xuyu Qian

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Mentions

159

Peak: 45 in Feb 2023

across 6 sources since Feb 2023

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1,834,768

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Feb 2023 – Mar 2024

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AI synopsis

What people are saying

Numerous discussions highlight specific points from the publication, with phrases like 'you can fuse a human brain-like collection of cells with an injured rat brain' illustrating the fascination with the implications of the research. The use of terms such as 'crazy' and 'fascinating' reflects excitement and underscores the significant potential for future applications in regenerative medicine.

AgreementModerate agreement

Many discussions reflect a positive outlook on the research, recognizing its significance in neuroscience.

InterestHigh interest

There is a high level of curiosity and enthusiasm, as several posts highlight the groundbreaking nature of the findings.

EngagementModerate engagement

While posts are mostly supportive, some indicate a surface-level understanding rather than delving deeply into methodologies.

ImpactHigh impact

Users perceive the research as having a substantial impact on the field of brain repair and rehabilitation.

Abstract in brief

Human brain organoids derived from pluripotent stem cells show potential for brain repair and can mimic structural features of the brain.
This study reveals that these organoids can integrate into the adult rat visual system, forming connections with the host's retina and other visual regions after transplantation into damaged areas.
The findings indicate that the transplanted organoid neurons can respond to visual stimuli, suggesting they may restore functional capacity following cortical injuries.

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NeuroVascuLab

@NeuroVascuLab · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell https://t.co/UueceTYGC0

Mar 16, 2024 · 1 like · 566 followers View post →

Darian Draught.

@98Draught98 · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJga…

Oct 31, 2023 · 7 shares · 183 followers View post →

ArghaK Das

@ArghakDas · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJga…

Oct 31, 2023 · 7 shares · 104 followers View post →

Namphungo

@Waterbee_19 · X

RT @CellPressNews: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJg…

Oct 30, 2023 · 4 shares View post →

Ingridlly

@Ingridlly · X

RT @CellPressNews: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJg…

Oct 29, 2023 · 4 shares · 191 followers View post →

octavio

@dontavo66 · X

RT @CellPressNews: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJg…

Oct 29, 2023 · 4 shares · 329 followers View post →

Alessandro Blasimme

@a_blasimme · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJga…

Oct 29, 2023 · 7 shares · 488 followers View post →

N. Moncada

@ChiguiMedicina · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJga…

Oct 29, 2023 · 7 shares · 274 followers View post →

Vladimir Martínez-Álvarez

@vladiberto · X

RT @CellPressNews: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJg…

Oct 29, 2023 · 4 shares · 239 followers View post →

Mustafa O. Guler

@mustafaoguler · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system by @DennisJga…

Oct 29, 2023 · 7 shares · 2,403 followers View post →

Cell Stem Cell

@CellStemCell · X

Oct 29, 2023 · 18 likes · 7 shares · 58,539 followers View post →

Cell Press

@CellPressNews · X

Oct 29, 2023 · 19 likes · 4 shares · 161,346 followers View post →

David Krizaj

@dkrizaj · X

????! https://t.co/1VuoWvsFwA

Jul 24, 2023 · 186 followers View post →

ingenious targeting laboratory

@GeneTargeting · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system Jgamadze, et al. Cell Stem Cell. #brainresearch #neurologicaldisorders #neurologicalrehabilitation #neurologicalconditions #brainscience #stemcellresearch https://t.co/XIhcuhjJa8

Apr 27, 2023 · 635 followers View post →

Dr. Thomas Ichim

@exosome · X

How crazy is this....they showed that at some level you can fuse a human brain-like collection of cells with an injured rat brain and that they work together https://t.co/mSCGI6Btmr

Mar 22, 2023 · 3 likes · 33,024 followers View post →

Bryan Bishop

@kanzure · X

"Structural and functional integration of human forebrain organoids with the injured adult rat visual system" https://t.co/DoUQssY99X

Mar 6, 2023 · 1 like · 15,746 followers View post →

daniel franqueira fernandez

@danielfranquei1 · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/…

Feb 27, 2023 · 5 shares · 5 followers View post →

Terence Robinson

@TERENCER · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell #visual snow #eyes #vs #optometry #brain https://t.co/boRE15tzIi

Feb 27, 2023 · 1 like · 4,536 followers View post →

Calira (formerly Clustermarket)

@calirasoftware · X

https://t.co/U1Pnt3j2Em https://t.co/gJWQTdQ2Iz

Feb 21, 2023 · 2,620 followers View post →

三輪書店＿眼科書籍編集室

@miwashoten_gnk · X

◎原著論文→Dennis Jgamadze, James T Lim, Zhijian Zhang, et al. : Structural and functional integration of human forebrain organoids with the injured adult rat visual system. Cell Stem Cell 30(2) : 137-152, 2023. DOI: 10.1016/j.stem.2023.01.004 https://t.co/4y3DSEsYOC

Feb 21, 2023 · 2,824 followers View post →

Penn NGG

@PennNGG · X

A nice thread about the recent publication "Structural and functional integration of human forebrain organoids with the injured adult rat visual system" from a large collaboration of #PennNGG labs! https://t.co/H7FdJwhORG

Feb 13, 2023 · 5 likes · 1,799 followers View post →

Katrina Espinar

@kespinar90 · X

RT @SinaiStemCell: A fascinating new paper out of the Chen lab - published in Cell Stem Cell - demonstrates that human brain #organoids tra…

Feb 13, 2023 · 5 shares · 1,550 followers View post →

Michael Rendl

@rendlm · X

RT @SinaiStemCell: A fascinating new paper out of the Chen lab - published in Cell Stem Cell - demonstrates that human brain #organoids tra…

Feb 13, 2023 · 5 shares · 219 followers View post →

Jibran Khokhar

@DrJKhokhar · X

RT @SinaiStemCell: A fascinating new paper out of the Chen lab - published in Cell Stem Cell - demonstrates that human brain #organoids tra…

Feb 13, 2023 · 5 shares · 10,817 followers View post →

The ReNeural Project

@ReNeural · X

RT @SinaiStemCell: A fascinating new paper out of the Chen lab - published in Cell Stem Cell - demonstrates that human brain #organoids tra…

Feb 13, 2023 · 5 shares · 429 followers View post →

Friedman Brain Institute

@SinaiBrain · X

RT @SinaiStemCell: A fascinating new paper out of the Chen lab - published in Cell Stem Cell - demonstrates that human brain #organoids tra…

Feb 13, 2023 · 5 shares · 12,275 followers View post →

Mount Sinai Stem Cell

@SinaiStemCell · X

Feb 13, 2023 · 8 likes · 5 shares · 473 followers View post →

Miguel Ángel Sogorb

@MASogorb · X

Organoide de cerebro humano trasplantado a un cerebro de rata https://t.co/1gUFMxnGa4 Más información: Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/u5iSuQO6CG

Feb 11, 2023 · 158 followers View post →

NeuroStemCells

@NeuroStemCell · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/QBPukmhbPC

Feb 7, 2023 · 536 followers View post →

Center for Infectious Disease & Nursing Innovation

@JHUCIDNI · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell https://t.co/xggpcc2tPR

Feb 6, 2023 · 1,687 followers View post →

Roger Blackwell

@rogerablackwell · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/gBD19cAPWp

Feb 6, 2023 · 2,307 followers View post →

Waseem

@ossaymayas · X

REFERENCES https://t.co/cDiN6uWlME

Feb 6, 2023 · 17 followers View post →

Hiromona

@hirombrain · X

RT @NeuroscienceNew: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgama…

Feb 5, 2023 · 4 shares · 345 followers View post →

Dr Imran Sheikh

@DrImranSheikh · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/T1u7d2bDg8 https://t.co/8ODiMUeBro

Feb 5, 2023 · 24,156 followers View post →

Sergei Giam

@SergeiGiam · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/v768iI3ocn

Feb 5, 2023 View post →

Dr. Alexandra A. de Sousa

@AleAliSousa · X

RT @seeingwithsound: Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.…

Feb 5, 2023 · 1 share · 488 followers View post →

#RaviVisvesvarayaSharadaPrasad #Telecom #InfoTech

@rvp · X

RT @NeuroscienceNew: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgama…

Feb 4, 2023 · 4 shares · 4,867 followers View post →

Jason Socrates Bardi

@JasonBardi · X

@IntuitMachine These are organic biological replacements, of course, and the work wasn't even concerned with "function" in the sense of a functioning visual cortex where you are restoring vision to blind rats. Here they were looking just for basic functional integration https://t.co/GYRYJ89gwi

Feb 4, 2023 · 913 followers View post →

Jason Socrates Bardi

@JasonBardi · X

@IntuitMachine Interestingly, I just wrote this week about researchers at U.Penn who replaced a piece of rat brain with a lab-grown organoid. To do functional replacements in humans? Hopefully. Someday. But the whole brain? I'll guess never. 10.1016/j.stem.2023.01.004 https://t.co/wb58K1VQhs https://t.co/URd1f6bGRv

Feb 4, 2023 · 1 like · 913 followers View post →

Epigenética

@Epigenetica · X

New in Pubmed: "Structural and functional integration of human forebrain organoids with the injured adult rat visual system" https://t.co/v0EDQ5DPMD

Feb 4, 2023 · 623 followers View post →

Phage Papers

@Phage_Papers · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/YmVnwpYl2P

Feb 4, 2023 · 646 followers View post →

The vOICe vision BCI

@seeingwithsound · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/TR2oJmkEUl "Human brain organoids integrate with the injured visual cortex of adult rats", "respond to host visual stimulation and adopt feature selectivity"

Feb 4, 2023 · 1 like · 1 share · 3,735 followers View post →

SCimPULSE Foundation

@ScimPulse · X

RT @BioDynaMo_org: Structural and functional integration of human forebrain organoids with the injured adult rat visual system

Feb 4, 2023 · 1 share · 150 followers View post →

BioDynaMo

@BioDynaMo_org · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/8Aw5ZRk54G

Feb 4, 2023 · 1 share · 162 followers View post →

Matt Kennedy

@mekapk_kennedy · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell https://t.co/iLq8c8YBxQ

Feb 3, 2023 · 43 followers View post →

Mt.HoodVintage

@MtHoodVintage · X

RT @NeuroscienceNew: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgama…

Feb 3, 2023 · 4 shares · 6,040 followers View post →

ごんごん

@gongonKS · X

RT @NeuroscienceNew: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgama…

Feb 3, 2023 · 4 shares · 3,306 followers View post →

Lucky Mendez

@lucky_mendez3 · X

RT @NeuroscienceNew: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgama…

Feb 3, 2023 · 4 shares · 318 followers View post →

Neuroscience News

@NeuroscienceNew · X

“Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Jgamadze et al. Cell Stem Cell https://t.co/RFqejDI1eV

Feb 3, 2023 · 7 likes · 4 shares · 505,831 followers View post →

CopperKettle

@Artyom_Yekat · X

RT @neuroliege: Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell…

Feb 3, 2023 · 1 share · 384 followers View post →

Mark Borris Aldonza (@precursorcell.bsky.social

@PrecursorCell · X

RT @CellStemCell: Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/…

Feb 3, 2023 · 5 shares · 1,386 followers View post →

Brett L. Foster

@brettlfoster · X

RT @PennNSG: Check out the latest publication from Isaac Chen MD, John Wolf PhD, and residents @RachelBlueMD and Ben Jiahe Gu MD! Structur…

Feb 3, 2023 · 2 shares · 2,235 followers View post →

Laurent Nguyen

@neuroliege · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell https://t.co/ls9Quls71I

Feb 3, 2023 · 17 likes · 1 share · 3,026 followers View post →

Cell Stem Cell

@CellStemCell · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/LGUJ8LikGw

Feb 3, 2023 · 20 likes · 5 shares · 58,539 followers View post →

Rachel Blue MD

@RachelBlueMD · X

RT @PennNSG: Check out the latest publication from Isaac Chen MD, John Wolf PhD, and residents @RachelBlueMD and Ben Jiahe Gu MD! Structur…

Feb 3, 2023 · 2 shares · 1,212 followers View post →

Penn Neurosurgery

@PennNSG · X

Feb 3, 2023 · 10 likes · 2 shares · 9,689 followers View post →

/r/Neuroscience

@neuroreddit · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system (02/02/2023) https://t.co/WLhVTaxspo

Feb 3, 2023 · 6 followers View post →

@RegMeD_Brighton

@RegmedB · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system: Cell Stem Cell https://t.co/S03OrEleQ2

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@operationoxygen · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/LnDatoI5NX

Feb 2, 2023 · 4,720 followers View post →

Takei Lab

@LabTakei · X

Structural and functional integration of human forebrain organoids with the injured adult rat visual system https://t.co/P8DUZfbprJ

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Structural and functional integration of human forebrain organoids with the injured adult rat visual system.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Restoration of Brain Functions Post-Mortem: A Scientific Breakthrough

ТЕХНО-НОВОСТИ | МОЗГ ЧЕЛОВЕКА ВНЕДРИЛИ КРЫСАМ ⚛ РОБОПЁС ДЁШЕВО⚛ КОСМИЧЕСКИЕ ПАРУСА⚛ КОНЕЦ BOEING-747