Int J Mol Sci January 2023 PMID 36768703

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress.

Yeong-Min Yoo, Seong Soo Joo

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Mentions

Peak: 8 in Nov 2024

across 3 sources since Jan 2023

Extended reach

7,581

potential audience

Total likes

110

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4,931

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Jan 2023 – Nov 2024

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AI synopsis

What people are saying

The analysis reflects general agreement on melatonin's neuroprotective potential, with posts emphasizing its ability to regulate ER stress as a 'crucial' factor in treating neurodegeneration. The tone is somewhat optimistic but remains straightforward, indicating solid interest without deep technical debates or calls for immediate change.

AgreementStrong agreement

Most discussions indicate strong agreement with the publication's findings on melatonin's potential in neurodegenerative disease modulation.

InterestModerate interest

Posts show moderate interest, primarily focusing on the protective role of melatonin and its therapeutic potential.

EngagementModerate engagement

Comments reflect some depth by highlighting mechanisms like ER stress regulation but lack detailed critique or alternative perspectives.

ImpactModerate impact

The discussions seem to recognize the importance of the findings, though without widespread urgency or calls to action.

Abstract in brief

As people age, their risk for neurodegenerative diseases like Parkinson's, Alzheimer's, and other chronic conditions increases, and endoplasmic reticulum (ER) stress is linked to these diseases.
Melatonin, a hormone mainly produced in the pineal gland, has various biological roles including regulating sleep, immunity, and acting as an antioxidant, but its potential to influence ER stress in neurons is not well-studied.
Research suggests that melatonin can protect neurons from ER stress by targeting molecules like CHOP, PERK, and GRP78, indicating its potential in treating or preventing neurodegenerative diseases.]

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Dr Carlos Gonzalez · Nov 27, 2024 89 views

Melatonin's Role in Neurodegenerative Disease Prevention and Therapy

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Dr Carlos Gonzalez · Nov 27, 2024 23 views

Role of Sleep and Melatonin in Preventing Neurodegenerative Diseases

This video discusses the importance of sleep for our body. It explores how aging affects the nervous system through oxidative stress and mitochondrial issues, and how melatonin can regulate autophagy to protect against…

Dr Carlos Gonzalez · Nov 27, 2024 14 views

Melatonin's Role in Neurodegenerative Disease Prevention and Treatment

This video discusses the importance of sleep and the potential of melatonin to protect against neurodegenerative diseases by regulating autophagy, helping to clear damaged proteins and maintain neuron health.

Dr Carlos Gonzalez · Nov 27, 2024 11 views

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@Orlando_uy · X

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress https://t.co/dwtf4Ofzhd

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Orlando_uy

@Orlando_uy · X

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress https://t.co/dwtf4Ofzhd

Apr 5, 2023 · 1 like · 692 followers View post →

Orlando_uy

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Lala

@CNSProteostasis · X

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress https://t.co/e8woaOntZH https://t.co/7ihViVEBPn

Feb 28, 2023 · 20 followers View post →

MyJournals

@myjournals · X

IJMS, Vol. 24, Pages 2381: Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress https://t.co/ZCDZSiD1Ci

Jan 25, 2023 · 557 followers View post →

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress.

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