Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,22). But there’s a lot to think about at the bedside with pts. Here’s our approach to risk stratification & lab monitoring https://t.co/KCw0mRml6R #dermtwitter https://t.co/mCPxqvPOWg
A Review on the Safety of Using JAK Inhibitors in Dermatology: Clinical and Laboratory Monitoring.
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Mar 2023 – Feb 2024Where it's discussed
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What people are saying
Discussions demonstrate a balanced tone, with posts like @drshawnkwatra expressing enthusiasm about research contributions, and others emphasizing the importance of careful risk assessment in practice. The tone and context communicate a meaningful engagement with the article’s implications for dermatological treatment, emphasizing the need for awareness and diligent monitoring.
Most discussions recognize the importance and emerging role of JAK inhibitors in dermatology, reflecting general agreement with the article’s focus on safety and monitoring.
Posts show moderate interest by discussing practical implications and new developments, indicating curiosity about how to implement findings.
Participants reference specific research areas, such as risk stratification and monitoring protocols, suggesting a participative discussion that delves into clinical applications.
The discussions highlight the significance of the safety review for current and future clinical practice, emphasizing its influence on patient management strategies.
Abstract in brief
- JAK inhibitors are effective treatments for various skin conditions but have safety concerns, leading the FDA to issue a black box warning based on studies in rheumatoid arthritis patients.
- The safety profile of approved JAK inhibitors like abrocitinib, upadacitinib, baricitinib, deucravacitinib, and topical ruxolitinib show relatively low rates of serious adverse events such as blood clots, infections, and skin cancers, mostly occurring in patients with preexisting risk factors.
- Clinicians should conduct careful initial screening and regular laboratory monitoring, considering patients' individual risk factors to minimize the potential adverse effects associated with JAK inhibitor therapy in dermatology.
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Most liked on X and BlueskyA Review on the Safety of Using JAK Inhibitors in #Dermatology: Clinical and Laboratory Monitoring https://t.co/c9GIjY76dq https://t.co/YyzfbEFKCF
So glad that @drshawnkwatra is involved with research like this! Helping to provide guidance on JAK inhibitors for #atopicdermatitis #psoriasis #hidradenitissupporativa + more https://t.co/tn6e6K4A3E
RT @drshawnkwatra: Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,2…
RT @drshawnkwatra: Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,2…
RT @imedverse: A Review on the Safety of Using JAK Inhibitors in #Dermatology: Clinical and Laboratory Monitoring https://t.co/c9GIjY76dq…
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Safety and Monitoring of JAK Inhibitors in Dermatology Treatments
JAK inhibitors effectively treat various skin conditions but pose safety concerns. This review discusses clinical and laboratory monitoring strategies to minimize risks like blood clots, infections, and skin cancers…
RT @imedverse: A Review on the Safety of Using JAK Inhibitors in #Dermatology: Clinical and Laboratory Monitoring https://t.co/c9GIjY76dq…
A Review on the Safety of Using JAK Inhibitors in #Dermatology: Clinical and Laboratory Monitoring https://t.co/c9GIjY76dq https://t.co/YyzfbEFKCF
RT @drshawnkwatra: Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,2…
So glad that @drshawnkwatra is involved with research like this! Helping to provide guidance on JAK inhibitors for #atopicdermatitis #psoriasis #hidradenitissupporativa + more https://t.co/tn6e6K4A3E
RT @drshawnkwatra: Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,2…
RT @drshawnkwatra: Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,2…
Jak inhibitors are emerging in so many dermatology diseases & gaining approvals w/cross immune-axis activity (Th1,2,17,22). But there’s a lot to think about at the bedside with pts. Here’s our approach to risk stratification & lab monitoring https://t.co/KCw0mRml6R #dermtwitter https://t.co/mCPxqvPOWg