JAMA Cardiol April 2023 PMID 36790817

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care: Post Hoc Analysis of the LOOP Randomized Clinical Trial.

Søren Zöga Diederichsen, Lucas Yixi Xing, Diana My Frodi, Emilie Katrine Kongebro, Ketil Jørgen Haugan, Claus Graff, Søren Højberg, Derk Krieger, Axel Brandes, Lars Køber, Jesper Hastrup Svendsen

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Mentions

79
Peak: 55 in Feb 2023
across 5 sources since Feb 2023

Extended reach

366,303
potential audience

Total likes

230

Video views

6,234

Mentions per month

Feb 2023 – Jul 2024

Where it's discussed

  • X / Twitter66 posts
  • News6 articles
  • Blogs3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reflect a cautious but engaged perspective on the article, with many posts emphasizing the high prevalence of bradyarrhythmias in older adults and noting that increased detection and pacemaker implantation did not reduce syncope or sudden death, illustrating both interest and skepticism about the clinical significance of such screening practices. Word choices such as 'interesting,' 'thought-provoking,' and mentions of 'no change in outcomes' highlight a balanced tone of curiosity tempered with critical evaluation.

AgreementModerate agreement

Most posts acknowledge the study's findings that while bradyarrhythmias are prevalent and their detection leads to more pacemaker implants, it doesn't necessarily improve clinical outcomes, indicating tempered agreement.

InterestModerate interest

Discussions show moderate interest, with many posts expressing curiosity or highlighting the significance of the findings but not delving deeply into specific technical details.

EngagementModerate engagement

Posts reflect active engagement through sharing summaries, asking questions, and referencing related studies or clinical implications, showing thoughtful participation.

ImpactModerate impact

The collective tone suggests the study could influence clinical practice by questioning the benefit of widespread detection without improved outcomes, indicating a moderate impact potential.

Abstract in brief

  • The study analyzed the prevalence and significance of bradyarrhythmias in older patients screened for atrial fibrillation (AF) using implantable loop recorders (ILR) compared to those receiving usual care.
  • Out of 6,004 participants, bradyarrhythmia was diagnosed in 172 individuals, with a significantly higher rate in the ILR group (208 cases) compared to the control group (38 cases), indicating the effectiveness of ILR in detection.
  • Key findings revealed that risk factors for bradyarrhythmia included older age, male sex, and certain pre-existing health conditions, with the majority of diagnosed cases being asymptomatic.

Top posts

Most liked on X and Bluesky
JAMA Cardiology
@JAMACardio · X

In the randomized LOOP study, AF screening resulted in the coincidental diagnosis of sinus node dysfunction or atrioventricular block in 1 of 5 participants, along with increased pacemaker implantations, but no change in risk of syncope or sudden death. https://t.co/V5JK2iGlQV

Feb 15, 2023 · 30 likes · 10 shares · 47,791 followers View post →
Jason Andrade
@DrJasonAndrade · X

I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implant are for the more benign indications (sinus node dysfunction, low grade AV block) but récurrent syncope confined to no monitoring group https://t.co/PrQd9DZjLo

Feb 15, 2023 · 28 likes · 9 shares · 7,988 followers View post →
Prof Chris P Gale
@cpgale3 · X

Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no overall effect on syncope or sudden cardiovascular death: LOOP RCT substudy https://t.co/RB2VWLVDUA @JAMACardio

Feb 19, 2023 · 21 likes · 8 shares · 13,470 followers View post →
Bartosz Hudzik MD PhD FESC FACC
@BartoszHudzik · X

#Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their detection and treatment is not associated with reduced incidence of clinical #outcomes https://t.co/7qiWwiN1XZ #AFib #ILR #screening @JAMACardio @drjohnm https://t.co/Hn1aFETWXV

Feb 15, 2023 · 15 likes · 6 shares · 1,425 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 23, 2023 · 15 likes · 4 shares · 643 followers View post →
JAMA Cardiology
@JAMACardio · X

In the randomized LOOP study, AF screening resulted in the coincidental diagnosis of sinus node dysfunction or atrioventricular block in 1 of 5 participants, along with increased pacemaker implantations, but no change in risk of syncope or sudden death. https://t.co/p8iVenn1AA

Apr 17, 2023 · 10 likes · 2 shares · 47,791 followers View post →

All mentions

Willy Frick
@willyhfrick · X

@Toaster_Pastry I worry about overdiagnosis with continuous telemetry in unselected patients. For example: https://t.co/HVpwQAKBCL

Jun 22, 2023 · 1 like · 4,044 followers View post →
Alex Scripcariu
@alex_scripcariu · X

@bordistef @syamkumarmd @ecgrhythms @SergioPinski @narrowQRS @MDTolgaAksu @MattMelcherPA @DrV_Mann @SchakrabartiEP Very interesting. So what did you do ? Also this: https://t.co/wnWu5xbsHf

May 11, 2023 · 74 followers View post →
JAMA Cardiology
@JAMACardio · X

In the randomized LOOP study, AF screening resulted in the coincidental diagnosis of sinus node dysfunction or atrioventricular block in 1 of 5 participants, along with increased pacemaker implantations, but no change in risk of syncope or sudden death. https://t.co/p8iVenn1AA

Apr 17, 2023 · 10 likes · 2 shares · 47,791 followers View post →
Paco Tarazona
@Sabater71 · X

RT @FormigaFrancesc: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://…

Apr 13, 2023 · 2 shares · 1,219 followers View post →
Medtorek
@Medtorek · X

RT @FormigaFrancesc: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://…

Apr 13, 2023 · 2 shares · 13,856 followers View post →
Francesc Formiga
@FormigaFrancesc · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://t.co/lTwEjqa8rl a través de @JAMACardio @JAMANetwork TO BE ALERT @GeriMedMD @martinezvelilla @Elisabet_Snchz @Sabater71 @semeg_es @semeg_es @IcyfaSemi @Medtorek

Apr 13, 2023 · 3 likes · 2 shares · 1,945 followers View post →
Tardu Özkartal
@Tardu_Oezkartal · X

RT @SZDiederichsen: This poll

Apr 6, 2023 · 1 share · 45 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

This poll

Apr 6, 2023 · 5 likes · 1 share · 643 followers View post →
Luis Zurita G.
@LuisZuritaG · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://t.co/V3iW1r9njC vía @JAMACardio part of @JAMANetwork

Mar 8, 2023 · 6,430 followers View post →
Salisbury Hospital Research
@SDHResearch · X

RT @Artesia_RCT: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care Post…

Mar 6, 2023 · 1 share · 389 followers View post →
The ARTESiA Trial
@Artesia_RCT · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care Post Hoc Analysis of the LOOP Randomized Clinical Trial https://t.co/K8Ak768t5X

Mar 3, 2023 · 6 likes · 1 share · 321 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @ameeshisath: Thought provoking study in @JAMACardio In a post hoc analysis of the LOOP study, more bradyarryhtmias detected leading to…

Feb 26, 2023 · 1 share · 643 followers View post →
Ameesh Isath
@ameeshisath · X

Thought provoking study in @JAMACardio In a post hoc analysis of the LOOP study, more bradyarryhtmias detected leading to more pacemakers in the ILR group but no effect on sudden death or syncope! @seiiwaiEPmd @DrRhthm @SrihariNaiduMD @MalikMD10 https://t.co/3F9yP7nFiV

Feb 25, 2023 · 7 likes · 1 share · 2,144 followers View post →
Prabhakar Dorairaj
@prabhud19 · X

Prevalence & Prognostic Significance of Bradyarrhythmias in Patients -by Loop recorder in AF screening.https://t.co/SYV51Vcrkl via @JAMACardio part of @JAMANetwork Bradyarrhythmias may constitute risk markers,their detection and Rx isnt associated with fewer clinical outcomes

Feb 24, 2023 · 1 like · 1,624 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @SZDiederichsen: Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 24, 2023 · 4 shares · 534 followers View post →
Steve Stiles
@SteveStiles2 · X

RT @SZDiederichsen: Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 23, 2023 · 4 shares · 1,351 followers View post →
Elisa Haas, MD
@ElisaAHaas · X

RT @SZDiederichsen: Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 23, 2023 · 4 shares · 445 followers View post →
John Mandrola, MD
@drjohnm · X

RT @SZDiederichsen: Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 23, 2023 · 4 shares · 68,472 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

Thx @SteveStiles2 for this piece on our @JAMACardio paper on subclinical bradyarrhythmias https://t.co/WCtHN6rRjz

Feb 23, 2023 · 15 likes · 4 shares · 643 followers View post →
@investigando
@rocatanho · X

1 de c/5 personas mayores de 70a c/factores de riesgo CV pueden ser diagnosticadas c/bradiarritmias c/monitorización continua a largo plazo por FA #ILR #bradyarrhyhtmia #FA https://t.co/DozS8DpIAB a través de @JAMACardio part of @JAMANetwork

Feb 21, 2023 · 400 followers View post →
Linda
@wordfinga · X

RT @HeartOTXHeartMD: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care:…

Feb 20, 2023 · 3 shares · 4,596 followers View post →
Faby G.
@Fabiolaghh · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 20, 2023 · 8 shares · 411 followers View post →
#hellomynameis Shane
@drohanlon · X

"Bradyarrhythmias are highly common in older persons, and while these arrhythmias may constitute risk markers, their detection and treatment is not associated with reduced incidence of clinical outcomes." https://t.co/KmAQWukDae via @JAMACardio part of @JAMANetwork

Feb 20, 2023 · 1 like · 3,814 followers View post →
Vineet Sankhla
@vineetcardio · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 20, 2023 · 8 shares · 1,406 followers View post →
emily pastfield
@PASTIE81 · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 20, 2023 · 8 shares · 255 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 20, 2023 · 8 shares · 643 followers View post →
Darshan H Brahmbhatt
@Doctor_Darshan · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 19, 2023 · 8 shares · 1,484 followers View post →
Ankush Gupta
@DrAnkushG · X

RT @cpgale3: Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no o…

Feb 19, 2023 · 8 shares · 2,586 followers View post →
Prof Chris P Gale
@cpgale3 · X

Sinus node dysfunction & AV block occur in 1 in 5 people aged over 70 years, with increased implantation of pacemakers & no overall effect on syncope or sudden cardiovascular death: LOOP RCT substudy https://t.co/RB2VWLVDUA @JAMACardio

Feb 19, 2023 · 21 likes · 8 shares · 13,470 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @BSHeartFailure: Important message here … not directly HF but yet another example of how when we treat without evidence … we may not cha…

Feb 19, 2023 · 1 share · 643 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @ArashArya_EP: @EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and…

Feb 19, 2023 · 5 shares · 643 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @AAckerschottMD: Interesting post hoc analysis of the LOOP trial concerning the prognostic significance of bradyarrhythmias in patients…

Feb 19, 2023 · 1 share · 643 followers View post →
British Society for Heart Failure #theFword
@BSHeartFailure · X

Important message here … not directly HF but yet another example of how when we treat without evidence … we may not change outcomes. https://t.co/p9OGlmbMRL

Feb 19, 2023 · 2 likes · 1 share · 11,453 followers View post →
Ali Bozorgi
@BozorgiAli · X

RT @ArashArya_EP: @EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and…

Feb 19, 2023 · 5 shares · 1,445 followers View post →
Ansgar Ackerschott
@AAckerschottMD · X

Interesting post hoc analysis of the LOOP trial concerning the prognostic significance of bradyarrhythmias in patients screened for atrial fibrillation https://t.co/S8wRGYFqQf @JAMACardio @JAMANetwork

Feb 19, 2023 · 4 likes · 1 share · 24 followers View post →
javad mikaeili
@javadm20 · X

RT @ArashArya_EP: @EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and…

Feb 19, 2023 · 5 shares · 4,312 followers View post →
Shaojie Chen
@ShaojieChen1 · X

RT @ArashArya_EP: @EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and…

Feb 19, 2023 · 5 shares · 2,310 followers View post →
Frank Lindemann
@FrankLindemann3 · X

RT @ArashArya_EP: @EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and…

Feb 19, 2023 · 5 shares · 561 followers View post →
Arash Arya
@ArashArya_EP · X

@EPeeps_Bot #EPeeps @JAMACardio In this study, ILR screening led to a 6-fold increase in bradyarrhythmia diagnoses and a significant increase in pacemaker implantations compared with usual care but no change in the risk of syncope or sudden death! https://t.co/hhIrYFM8ld https://t.co/Y3jVUxThsA

Feb 19, 2023 · 9 likes · 5 shares · 1,831 followers View post →
Sandeep Gautam
@gautamsand · X

RT @HeartOTXHeartMD: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care:…

Feb 18, 2023 · 3 shares · 4,379 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @HeartOTXHeartMD: Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care:…

Feb 18, 2023 · 3 shares · 11,352 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care: Post Hoc Analysis of the LOOP Randomized Clinical Trial | Atrial Fibrillation https://t.co/xBewo0zFM0

Feb 18, 2023 · 8 likes · 3 shares · 39,653 followers View post →
So Sunny
@SoSunny14 · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 186 followers View post →
Yury Mareev
@YMareev · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 681 followers View post →
Andrea Di Marco
@Di_Marco_Andrea · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 257 followers View post →
Rxorcist
@RxWorkInProgres · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 46 followers View post →
thegellergroupEP
@thegellergroup · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 213 followers View post →
b bozorgnia MD
@bbnmd74 · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 568 followers View post →
Shunsuke Kuroda
@kuroda_shunsuke · X

LOOP RCTのサブ解析. 徐脈はAF患者の20%にみられた. 最も多いのはやはりSND. ILRでは多くの徐脈が見つかり、一部にPMIが行われたが, 両群に失神イベントの差はみられず. ILRは情報の宝庫だが、どうすればいいかわかっていない事が多い。https://t.co/Cl8ELJebc0 via @JAMACardio part of @JAMANetwork

Feb 16, 2023 · 4 likes · 696 followers View post →
CardioInfo
@Cardioinfo_it · X

RT @RasoiniR: Intermittent loop recorder screening led to a 6-fold increase in bradyarrhythmia diagnoses and a significant increase in pace…

Feb 16, 2023 · 2 shares · 9,220 followers View post →
Konstantinos Vlachos
@vlachoskonstan1 · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 684 followers View post →
Raffaele Rasoini
@RasoiniR · X

Intermittent loop recorder screening led to a 6-fold increase in bradyarrhythmia diagnoses and a significant increase in pacemaker implantations compared with usual care but no change in the risk of syncope or sudden death. https://t.co/9kuS69lUl6 via @JAMACardio

Feb 16, 2023 · 4 likes · 2 shares · 424 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

@KamalKotakMD @DrJasonAndrade Reported PM implants by arrhythmia subtypes (figs 3-4 https://t.co/WCtHN6rRjz) Not really enough data to report subsequent outcomes by arrhythmia subgroups. Could look more into this...

Feb 16, 2023 · 2 likes · 643 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 643 followers View post →
Scavée C
@ScaveeC · X

RT @DrJasonAndrade: I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implan…

Feb 16, 2023 · 9 shares · 367 followers View post →
Francesc Formiga
@FormigaFrancesc · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://t.co/TmU56xWJz2 a través de @JAMACardio part of @JAMANetwork

Feb 16, 2023 · 1,945 followers View post →
Jason Andrade
@DrJasonAndrade · X

I find this paper incredibly interesting but need to digest it more. First blush - half the reason for pacemaker implant are for the more benign indications (sinus node dysfunction, low grade AV block) but récurrent syncope confined to no monitoring group https://t.co/PrQd9DZjLo

Feb 15, 2023 · 28 likes · 9 shares · 7,988 followers View post →
Mattia Galli
@MattiaGalli10 · X

RT @BartoszHudzik: #Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their…

Feb 15, 2023 · 6 shares · 3,183 followers View post →
Jeff Wilkins MD
@tbrilw · X

RT @BartoszHudzik: #Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their…

Feb 15, 2023 · 6 shares · 396 followers View post →
Søren Zöga Diederichsen
@SZDiederichsen · X

RT @BartoszHudzik: #Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their…

Feb 15, 2023 · 6 shares · 643 followers View post →
Narut
@prasitlumkum · X

RT @JAMACardio: In the randomized LOOP study, AF screening resulted in the coincidental diagnosis of sinus node dysfunction or atrioventric…

Feb 15, 2023 · 10 shares · 194 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

通常治療群「徐脈」診断とCV死亡間には相関認めず。 https://t.co/UgKgDqfR8P

Feb 15, 2023 · 1 like · 4,901 followers View post →
Boback Ziaeian
@boback · X

Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs... https://t.co/WomzSoq9aJ via @JAMACardio part of @JAMANetwork

Feb 15, 2023 · 1 like · 3,371 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

RT @BartoszHudzik: #Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their…

Feb 15, 2023 · 6 shares · 12,118 followers View post →
Bartosz Hudzik MD PhD FESC FACC
@BartoszHudzik · X

#Bradyarrhythmias are highly common in #older persons, and while these #arrhythmias may constitute #risk #markers, their detection and treatment is not associated with reduced incidence of clinical #outcomes https://t.co/7qiWwiN1XZ #AFib #ILR #screening @JAMACardio @drjohnm https://t.co/Hn1aFETWXV

Feb 15, 2023 · 15 likes · 6 shares · 1,425 followers View post →
JAMA Cardiology
@JAMACardio · X

In the randomized LOOP study, AF screening resulted in the coincidental diagnosis of sinus node dysfunction or atrioventricular block in 1 of 5 participants, along with increased pacemaker implantations, but no change in risk of syncope or sudden death. https://t.co/V5JK2iGlQV

Feb 15, 2023 · 30 likes · 10 shares · 47,791 followers View post →