Brain Behav March 2023 PMID 36791212

Posterior cingulate cortex targeted real-time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default-mode network in PTSD.

Jonathan M Lieberman, Daniela Rabellino, Maria Densmore, Paul A Frewen, David Steyrl, Frank Scharnowski, Jean Théberge, Richard W J Neufeld, Christian Schmahl, Rakesh Jetly, Sandhya Narikuzhy, Ruth A Lanius, Andrew A Nicholson

Mentions

17
Peak: 6 in Feb 2023
across 4 sources since Feb 2023

Extended reach

16,606
potential audience

Total likes

14

Video views

195

Mentions per month

Feb 2023 – Sep 2025

Where it's discussed

  • X / Twitter6 posts
  • News5 articles
  • TikTok4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall discussions demonstrate enthusiasm for the research, with posts emphasizing the role of the posterior cingulate cortex in PTSD and expressing pride in publications. Words like 'proud', 'first-author', and tags of collaborators reflect a tone of achievement and significance, indicating strong interest and moderate engagement, while the focus on the study's implications suggests a moderate perceived impact.

AgreementModerate agreement

Most discussions express support or pride in the research, highlighting its importance and potential for PTSD treatment.

InterestHigh interest

Posts show high interest, with multiple mentions of publishing milestones and specific references to the research's relevance.

EngagementModerate engagement

Participants show moderate engagement by thanking collaborators and sharing personal mentions related to the publication.

ImpactModerate impact

The discussions hint at the significance of the research within the scientific community, though there is limited debate about broader implications.

Abstract in brief

  • Alterations in brain networks, particularly the default mode and salience networks, are linked to PTSD symptoms, with the posterior cingulate cortex (PCC) playing a key role in regulating these changes.
  • A study involved 14 PTSD patients and 15 healthy controls to measure PCC connectivity during neurofeedback sessions, comparing conditions where participants either regulated or observed PCC activity.
  • Findings reveal that, unlike healthy controls, the PTSD group exhibited stronger PCC connectivity with critical brain areas during regulation, suggesting these connections may underlie symptom improvements in PTSD patients.

Top posts

Most liked on X and Bluesky
Jonathan Lieberman
@jon__lieberman · X

Proud to be able to share my first 1st-author publication from my PhD thesis! Thanks to all my mentors and collaborators! @LaniusRuth @DrAndrewNichol1 @DrJeanTheberge @sandhya__n @PaulFrewen https://t.co/rS3gP7gZdD

Feb 15, 2023 · 11 likes · 1 share · 133 followers View post →
uOttawa Psychiatry | Psychiatrie
@uOPsychiatry · X

Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default‐mode network in PTSD @MacPsychiatry @uOPsychiatry @TheRoyalMHC @atlasveteransca https://t.co/vOFSsGfdPn

Feb 24, 2023 · 3 likes · 2 shares · 2,268 followers View post →
The Royal
@TheRoyalMHC · X

RT @uOPsychiatry: Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala,…

Feb 24, 2023 · 2 shares · 12,540 followers View post →
Ruth Lanius, MD, PhD
@LaniusRuth · X

RT @jon__lieberman: Proud to be able to share my first 1st-author publication from my PhD thesis! Thanks to all my mentors and collaborator…

Feb 16, 2023 · 1 share · 924 followers View post →
Adelina McCall, BSc, MSc
@addie_axon · X

RT @uOPsychiatry: Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala,…

Feb 24, 2023 · 2 shares · 329 followers View post →
Jean Theberge
@DrJeanTheberge · X

NeuroPIL collaborators @jon_lieberman, @LaniusRuth and @DrAndrewNichol1 show that posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default‐mode network in PTSD https://t.co/OljvNQWqDo

Feb 17, 2023 · 112 followers View post →

All mentions

Adelina McCall, BSc, MSc
@addie_axon · X

RT @uOPsychiatry: Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala,…

Feb 24, 2023 · 2 shares · 329 followers View post →
The Royal
@TheRoyalMHC · X

RT @uOPsychiatry: Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala,…

Feb 24, 2023 · 2 shares · 12,540 followers View post →
uOttawa Psychiatry | Psychiatrie
@uOPsychiatry · X

Posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default‐mode network in PTSD @MacPsychiatry @uOPsychiatry @TheRoyalMHC @atlasveteransca https://t.co/vOFSsGfdPn

Feb 24, 2023 · 3 likes · 2 shares · 2,268 followers View post →
Jean Theberge
@DrJeanTheberge · X

NeuroPIL collaborators @jon_lieberman, @LaniusRuth and @DrAndrewNichol1 show that posterior cingulate cortex targeted real‐time fMRI neurofeedback recalibrates functional connectivity with the amygdala, posterior insula, and default‐mode network in PTSD https://t.co/OljvNQWqDo

Feb 17, 2023 · 112 followers View post →
Ruth Lanius, MD, PhD
@LaniusRuth · X

RT @jon__lieberman: Proud to be able to share my first 1st-author publication from my PhD thesis! Thanks to all my mentors and collaborator…

Feb 16, 2023 · 1 share · 924 followers View post →
Jonathan Lieberman
@jon__lieberman · X

Proud to be able to share my first 1st-author publication from my PhD thesis! Thanks to all my mentors and collaborators! @LaniusRuth @DrAndrewNichol1 @DrJeanTheberge @sandhya__n @PaulFrewen https://t.co/rS3gP7gZdD

Feb 15, 2023 · 11 likes · 1 share · 133 followers View post →
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