Nat Commun February 2023 PMID 36797319

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.

Anne Edwards, Isaac Njaci, Abhimanyu Sarkar, Zhouqian Jiang, Gemy George Kaithakottil, Christopher Moore, Jitender Cheema, Clare E M Stevenson, Martin Rejzek, Petr Novák, Marielle Vigouroux, Martin Vickers, Roland H M Wouters, Pirita Paajanen, Burkhard Steuernagel

Mentions

17
Peak: 4 in Feb 2023
across 4 sources since Feb 2023

Extended reach

4,332
potential audience

Total likes

12

Video views

35

Mentions per month

Feb 2023 – May 2023

Where it's discussed

  • News10 articles
  • X / Twitter4 posts
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a positive outlook toward the article, with phrases like 'exciting story' and 'privileged to contribute,' highlighting enthusiasm for the scientific advances and their applications, as well as interest in the implications for crop safety and food security.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with phrases like 'exciting story' and 'privileged to contribute,' indicating agreement with its importance.

InterestHigh interest

Posts demonstrate high interest by highlighting the novel insights into β-L-ODAP biosynthesis and the potential for developing safer grass pea varieties.

EngagementModerate engagement

Posts mention specific contributions, such as genomic repeat annotation and biochemical analyses, showing a moderate level of engagement.

ImpactHigh impact

The discussions emphasize the potential impact on food security and toxin reduction in grass pea, indicating high perceived importance.

Abstract in brief

  • Grass pea (Lathyrus sativus) is a nutrient-dense protein source that can thrive in extreme weather conditions, making it important for food security in regions like Ethiopia and India.
  • The crop faces challenges such as limited genetic resources and the risk of neurolathyrism due to the neurotoxin β-L-ODAP associated with its consumption.
  • A new long-read genome assembly of L. sativus has mapped the biosynthetic pathway of β-L-ODAP, revealing key interactions between enzymes that could help develop safer grass pea varieties with reduced toxin levels.

Top posts

Most liked on X and Bluesky
Macas lab
@MacasLab · X

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileged to contribute genomic repeat annotation to this exciting story. Supported by @ELIXIRCZ. https://t.co/68mSOwRWy5

Feb 17, 2023 · 11 likes · 2 shares · 459 followers View post →
André Marques
@marques_et_al · X

RT @MacasLab: Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileg…

Feb 17, 2023 · 2 shares · 1,989 followers View post →
Europe PMC articles
@EuropePMC · X

New from #BBSRC https://t.co/bekShjm7KP Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.

Feb 19, 2023 · 1,552 followers View post →
Martin Vickers
@MartinjVickers · X

RT @MacasLab: Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileg…

Feb 21, 2023 · 2 shares · 286 followers View post →

All mentions

Martin Vickers
@MartinjVickers · X

RT @MacasLab: Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileg…

Feb 21, 2023 · 2 shares · 286 followers View post →
Europe PMC articles
@EuropePMC · X

New from #BBSRC https://t.co/bekShjm7KP Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.

Feb 19, 2023 · 1,552 followers View post →
André Marques
@marques_et_al · X

RT @MacasLab: Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileg…

Feb 17, 2023 · 2 shares · 1,989 followers View post →
Macas lab
@MacasLab · X

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus. @NatureComms Privileged to contribute genomic repeat annotation to this exciting story. Supported by @ELIXIRCZ. https://t.co/68mSOwRWy5

Feb 17, 2023 · 11 likes · 2 shares · 459 followers View post →