Mol Cancer February 2023 PMID 36810098

Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment.

Bo Wu, Xiang Shi, Meixi Jiang, Hongxu Liu

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Mentions

2
Peak: 1 in Mar 2023
across 2 sources since Mar 2023

Extended reach

552
potential audience

Total likes

0

Video views

18

Mentions per month

Mar 2023 – Jul 2023

Where it's discussed

  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

Discussions reflect both interest and skepticism, with posts referencing the potential therapeutic targets discussed in the publication, such as immune checkpoint interactions, but also point out issues like citing a retracted paper, which tempers the perceived impact and depth of engagement. The tone varies from cautious optimism to critical concern, influencing the overall moderate scores.

AgreementNeither agree nor disagree

The discussions show mixed reactions; some users acknowledge the importance of understanding tumor-immune interactions, while others express skepticism about certain aspects or point out issues like the citation of retracted papers.

InterestModerate interest

There is moderate interest mainly centered around the significance of targeting cancer stem cells and immune interactions, but some posts show limited enthusiasm or focus on administrative concerns.

EngagementModerate engagement

Several posts delve into the details, such as the role of immune checkpoints and extracellular vesicles, indicating a moderate level of deep engagement.

ImpactModerate impact

The posts highlight that this research could influence future cancer therapies, but some are cautious, indicating a perception of potential rather than immediate groundbreaking change.

Abstract in brief

  • Cancer stem cells (CSCs) are a major challenge in cancer treatment because they promote tumor growth, recurrence, and resistance to therapies due to their unique stem-like properties.
  • CSCs interact with immune cells and the tumor microenvironment (TME) by using immune checkpoints and releasing various substances like extracellular vesicles, growth factors, and cytokines to evade immune system attacks.
  • Understanding the molecular mechanisms of these interactions offers potential for developing new therapies that target the crosstalk between CSCs and the immune system to improve cancer treatment outcomes.

Top posts

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scite Reference Check
@sciterefcheck · X

We've detected a paper from Molecular Cancer that cites a retracted paper post-retraction. Citing paper: https://t.co/u5aWrx92oP Retracted paper: https://t.co/5GPicvTZrF

Mar 24, 2023 · 534 followers View post →

All mentions

scite Reference Check
@sciterefcheck · X

We've detected a paper from Molecular Cancer that cites a retracted paper post-retraction. Citing paper: https://t.co/u5aWrx92oP Retracted paper: https://t.co/5GPicvTZrF

Mar 24, 2023 · 534 followers View post →