PubHawk
Environ Health February 2023 PMID 36814257

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS).

Veronika Ehrlich, Wieneke Bil, Rob Vandebriel, Berit Granum, Mirjam Luijten, Birgitte Lindeman, Philippe Grandjean, Andreas-Marius Kaiser, Ingrid Hauzenberger, Christina Hartmann, Claudia Gundacker, Maria Uhl

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Mentions

33
Peak: 11 in Mar 2023
across 3 sources since Feb 2023

Extended reach

63,057
potential audience

Total likes

28

Video views

5

Mentions per month

Feb 2023 – Oct 2025

Where it's discussed

  • X / Twitter23 posts
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  • YouTube1 videos

AI synopsis

What people are saying

The group collectively shows strong agreement with the concerns raised about PFAS's immunotoxic effects, supported by detailed references to pathways and research findings. Their tone and choice of words, such as 'substantial evidence' and 'forever chemicals,' emphasize the seriousness and relevance of the issue, illustrating both high interest and impactful discussions on environmental health.

AgreementStrong agreement

Many discussions clearly support the harmful effects of PFAS and highlight the need for precaution, indicating strong agreement on the publication's concerns.

InterestHigh interest

The posts display high curiosity and concern about the health impacts and mechanisms of PFAS, showing active engagement with the subject.

EngagementModerate engagement

Participants reference specific pathways and studies, demonstrating a moderate level of personal investment and depth in discussing immunotoxicity.

ImpactHigh impact

The discussions emphasize the significance of PFAS's widespread presence and their potential to influence public health policies, denoting high impact.

Abstract in brief

  • The text explains that per- and polyfluoroalkyl substances (PFAS) are widespread and persistent chemicals that pose public health concerns due to their potential to affect the immune system, including reduced antibody responses and possible immunosuppression or enhancement.
  • The review aims to explore the mechanisms behind PFAS-related immunotoxicity, focusing on processes such as cell signaling, nuclear receptor modulation (like NFB and PPARs), calcium signaling, immune cell balance, oxidative stress, and fatty acid metabolism.
  • A literature search from 2018 to 2021 identified 487 studies, with selected research examining how PFAS impact immune functions, highlighting the complexity and need for further understanding of their immunotoxic effects.]
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Top posts

Most liked on X and Bluesky
PfoaProject NY
@pfoaprojectny1 · X

"Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epidemiological studies, supporting that various #PFAS, not only PFOA and PFOS, affect multiple aspects of the immune system." https://t.co/lXzWn1vk2D

Mar 2, 2023 · 14 likes · 7 shares · 2,775 followers View post →
Alzhacker
@Alzhacker · X

PFASの免疫毒性の経路に関する考察 2023 https://t.co/JBCWnXYOpF PFASが免疫系の複数の側面に影響を及ぼすことを示す証拠は十分にあり、PFOAとPFOSだけでなく、PFASファミリーの他のメンバーもヒトの免疫機能を変化させるという全体的な結論を支持している。 https://t.co/WpsmMRv9oO

Jul 10, 2024 · 11 likes · 2 shares · 33,053 followers View post →
andrew watterson
@aew1aew1 · X

27/2/23. Ehrlich V et al. Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS). Environ Health 22, 19 (2023). Various PFAS not just PFOA and PFOS affect the immune system https://t.co/v1cP4go8QQ

Feb 27, 2023 · 2 likes · 1 share · 730 followers View post →
JohnsonAndToxin
@JandTContent · X

@Robertvegan7 Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/scNlZdBupV

Dec 2, 2023 · 1 like · 1 share · 1,033 followers View post →
Hazards Campaign #CovidIsAirborne #Ventil8Filter
@hazardscampaign · X

RT @aew1aew1: 27/2/23. Ehrlich V et al. Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS). Environ…

Mar 5, 2023 · 1 share · 6,739 followers View post →
Masami mel Kawamura Ph.D, IPP Okinawa
@sirenamel · X

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/a40NAXFTcZ #PFAS

Mar 2, 2023 · 2 shares · 4,381 followers View post →

All mentions

duder Pierloot
@duder113 · X

@petervanderhey6 @mboudry deze influencer is dan ook anti-wetenschap. Public health evaluation of PFAS exposures and breastfeeding: a systematic literature review. Toxicol Sci. 2023 Jul 28; Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS). Environ Health. 2023 Feb

Oct 29, 2025 · 282 followers View post →
Murasaki
@Everlasting_yu · X

RT @Alzhacker: PFASの免疫毒性の経路に関する考察 2023 https://t.co/JBCWnXYOpF PFASが免疫系の複数の側面に影響を及ぼすことを示す証拠は十分にあり、PFOAとPFOSだけでなく、PFASファミリーの他のメンバーもヒトの免疫機能を変…

Jul 10, 2024 · 2 shares · 48 followers View post →
nico
@nico_purr · X

RT @Alzhacker: PFASの免疫毒性の経路に関する考察 2023 https://t.co/JBCWnXYOpF PFASが免疫系の複数の側面に影響を及ぼすことを示す証拠は十分にあり、PFOAとPFOSだけでなく、PFASファミリーの他のメンバーもヒトの免疫機能を変…

Jul 10, 2024 · 2 shares · 1,110 followers View post →
Alzhacker
@Alzhacker · X

PFASの免疫毒性の経路に関する考察 2023 https://t.co/JBCWnXYOpF PFASが免疫系の複数の側面に影響を及ぼすことを示す証拠は十分にあり、PFOAとPFOSだけでなく、PFASファミリーの他のメンバーもヒトの免疫機能を変化させるという全体的な結論を支持している。 https://t.co/WpsmMRv9oO

Jul 10, 2024 · 11 likes · 2 shares · 33,053 followers View post →
JohnsonAndToxin
@JandTContent · X

@HerbsandDirt Definitely not... "Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)" https://t.co/scNlZdBupV

Jan 31, 2024 · 1,033 followers View post →
JohnsonAndToxin
@JandTContent · X

RT @JandTContent: @HerbsandDirt The poisons DO NOT destroy immune function so the injection site can't heal. Is the liability-free vaxx.…

Dec 17, 2023 · 1 share · 1,033 followers View post →
JohnsonAndToxin
@JandTContent · X

@HerbsandDirt The poisons DO NOT destroy immune function so the injection site can't heal. Is the liability-free vaxx. Agreed. Totally. 100%. "Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)" https://t.co/scNlZdBupV

Dec 16, 2023 · 1 share · 1,033 followers View post →
JohnsonAndToxin
@JandTContent · X

RT @JandTContent: @Robertvegan7 Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/sc…

Dec 3, 2023 · 1 share · 1,033 followers View post →
JohnsonAndToxin
@JandTContent · X

@Robertvegan7 Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/scNlZdBupV

Dec 2, 2023 · 1 like · 1 share · 1,033 followers View post →
Staatsontbosbeheer
@Ontbosbeheer · X

@Kiespijn777 @ZEMBLA Ah, volledig onschuldig... Vandaar al die uiterst strenge limieten... Zo maar een kleine zoekvraag op het internet: https://t.co/LHIvJXJIK2

Jul 1, 2023 · 45 followers View post →
Corporate America
@Corporatization · X

@TLAVagabond Informally called, "forever chemicals," because bacteria can't eat them; fire can't incinerate them; and water can't dilute them. They persist in soil forever. They're also a known carcinogen. And, what a shocker, PFAS also have pathways for immunotoxicity.https://t.co/n2dNKhvDDC

Mar 11, 2023 · 82 followers View post →
mykdr
@mykdra · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 5, 2023 · 7 shares · 78 followers View post →
Hazards Campaign #CovidIsAirborne #Ventil8Filter
@hazardscampaign · X

RT @aew1aew1: 27/2/23. Ehrlich V et al. Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS). Environ…

Mar 5, 2023 · 1 share · 6,739 followers View post →
CleanEarth4Kids.org
@CleanEarth4Kids · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 3, 2023 · 7 shares · 1,147 followers View post →
Haereticus Environmental Laboratory
@HaereticusL · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 3, 2023 · 7 shares · 292 followers View post →
James O'Connor
@nuffsaid_h2o · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 2, 2023 · 7 shares · 617 followers View post →
Dear Diary
@BluePoppyDiary · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 2, 2023 · 7 shares · 76 followers View post →
seki_yo
@seki_yo · X

RT @sirenamel: Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/a40NAXFTcZ #PFAS

Mar 2, 2023 · 2 shares · 1,368 followers View post →
Masami mel Kawamura Ph.D, IPP Okinawa
@sirenamel · X

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/a40NAXFTcZ #PFAS

Mar 2, 2023 · 2 shares · 4,381 followers View post →
Masami mel Kawamura Ph.D, IPP Okinawa
@sirenamel · X

RT @pfoaprojectny1: "Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epid…

Mar 2, 2023 · 7 shares · 4,381 followers View post →
PfoaProject NY
@pfoaprojectny1 · X

"Taken together, we show that there is substantial evidence from both in vitro and in vivo experimental as well as epidemiological studies, supporting that various #PFAS, not only PFOA and PFOS, affect multiple aspects of the immune system." https://t.co/lXzWn1vk2D

Mar 2, 2023 · 14 likes · 7 shares · 2,775 followers View post →
andrew watterson
@aew1aew1 · X

27/2/23. Ehrlich V et al. Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS). Environ Health 22, 19 (2023). Various PFAS not just PFOA and PFOS affect the immune system https://t.co/v1cP4go8QQ

Feb 27, 2023 · 2 likes · 1 share · 730 followers View post →
MyJournals
@myjournals · X

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) https://t.co/RmieV4cQ6x

Feb 22, 2023 · 554 followers View post →