Addict Sci Clin Pract February 2023 PMID 36829242

Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder.

Ashish P Thakrar, Tanya J Uritsky, Cara Christopher, Anna Winston, Kaitlin Ronning, Anna Lee Sigueza, Anne Caputo, Rachel McFadden, Jennifer M Olenik, Jeanmarie Perrone, M Kit Delgado, Margaret Lowenstein, Peggy Compton

Mentions

21
Peak: 5 in Mar 2023
across 2 sources since Feb 2023

Extended reach

30,245
potential audience

Total likes

55

Video views

14

Mentions per month

Feb 2023 – Feb 2024

Where it's discussed

  • X / Twitter19 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions mostly support the notion that short-acting opioids are a safe and effective addition to inpatient OUD treatment, with examples like references to reduced discharges and feasibility, and the tone conveys cautious optimism about adopting these methods in clinical settings.

AgreementModerate agreement

Most discussions highlight support for using short-acting opioids in treatment, reflecting agreement with the article's positive findings.

InterestModerate interest

Participants show moderate interest, as they discuss the safety and implications but do not deeply question the study’s methodology.

EngagementHigh engagement

Many contributions delve into specific outcomes and clinical implications, indicating active and in-depth engagement.

ImpactModerate impact

The discussions suggest that this research could influence clinical practices, especially in inpatient addiction care, though its long-term impact remains to be seen.

Abstract in brief

  • The study examined the safety and early outcomes of using short-acting opioid agonist treatment (sOAT) like oxycodone and hydromorphone for hospitalized patients with opioid use disorder, aiming to reduce patient discharges against medical advice due to withdrawal and pain.
  • Results showed that sOAT was generally safe, with only one case of naloxone use for oversedation and no falls reported, and patients had a lower rate of premature discharges (44%) and shorter hospital stays (median 5 days) compared to previous hospitalizations.
  • The approach was combined with efforts to start long-term treatments like methadone or buprenorphine, and data from the hospital demonstrated promising preliminary safety outcomes for using short-acting opioids as part of inpatient care for OUD.]

Top posts

Most liked on X and Bluesky
Shawn Cohen
@ShawnCohen_MD · X

The standard of care should be using opioids to treat withdrawal and allow people to get the care they need @especially_APT https://t.co/Oavqv2FHD2

Aug 8, 2023 · 23 likes · 1 share · 580 followers View post →
Paul Christine
@pauljchristine · X

Love attending on inpatient addiction consult service with @BMCAddictionMed Yesterday, we discussed @especially_APT et al's recent paper on the safety and preliminary efficacy of short-acting opioid use in hospitalized patients with OUD: https://t.co/e59IrWhzyG

Mar 3, 2023 · 15 likes · 3 shares · 583 followers View post →
Addiction Medicine Journal Club
@AddictionMedJC · X

The next Addiction Medicine Journal Club podcast about short-acting opioid agonists for opioid use disorder in the hospital is coming on Monday. Get the article from @ascp_journal and join the conversation. #addictionmedicine #journalclub #AMJC https://t.co/4dzMbdv0Qs

May 21, 2023 · 5 likes · 1 share · 354 followers View post →
Penn LDI
@PennLDI · X

Short-acting opioid agonist treatment (sOAT) for opioid use disorder (OUD) is safe & effective. LDI Fellows found that sOAT: ⬇️ patient directed discharges (PDDs) ⬆️ length of stay for PPDs ⬆️ rates of medication for OUD. Read more here: https://t.co/ALLbsTKSyQ

Mar 17, 2023 · 4 likes · 1 share · 8,301 followers View post →
Daniel Koffler, MD
@dmkoffler · X

@MedFactChecks @LaraAHayes @reverendofdoubt What’s the evidence that dilaudid “perpetuates opioid seeking”? Pubmed search just now on “hydromorphone” and “opioid use disorder” turned up nothing to support that but did find this study showing dilaudid use compatible with management of existing OUD https://t.co/AAD8knX6kT

Aug 6, 2023 · 2 likes · 1 share · 1,557 followers View post →
Miriam Harris, MD, MSc
@miriamh_harris · X

Important contribution assessing use of oxycodone & PO/IV hydromorphone for w/drawal in 23 hospitalized patients w/ OUD 1 episode of iatrogenic intoxication Increases in MOUD & completing hospitalization More aggressive w/drawal strategies are feasible https://t.co/pCDiblAp87

Feb 24, 2023 · 2 likes · 1 share · 1,259 followers View post →

All mentions

Addiction Medicine Journal Club
@AddictionMedJC · X

21. SOAT for OUD: Short-Acting Opioid Agonists for Opioid Use Disorder Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder. Addict Sci Clin Pract 18, 13 (2023). https://t.co/4dzMbdut0U

Oct 24, 2023 · 354 followers View post →
nali
@NaliJulia · X

RT @ShawnCohen_MD: The standard of care should be using opioids to treat withdrawal and allow people to get the care they need @especially_…

Aug 16, 2023 · 1 share · 2,782 followers View post →
Shawn Cohen
@ShawnCohen_MD · X

The standard of care should be using opioids to treat withdrawal and allow people to get the care they need @especially_APT https://t.co/Oavqv2FHD2

Aug 8, 2023 · 23 likes · 1 share · 580 followers View post →
Daniel Koffler, MD
@dmkoffler · X

@MedFactChecks @LaraAHayes @reverendofdoubt What’s the evidence that dilaudid “perpetuates opioid seeking”? Pubmed search just now on “hydromorphone” and “opioid use disorder” turned up nothing to support that but did find this study showing dilaudid use compatible with management of existing OUD https://t.co/AAD8knX6kT

Aug 6, 2023 · 2 likes · 1 share · 1,557 followers View post →
Keri D. Hager
@keridhager · X

RT @accpPPCprn: In a small, pilot study (n=23) a #PharmD led intervention to provide short acting opioid agonist tx for pts w/ #OUD was ass…

Jun 6, 2023 · 2 shares · 169 followers View post →
Lucas Hill, PharmD, FCCP
@HillPharmD · X

RT @accpPPCprn: In a small, pilot study (n=23) a #PharmD led intervention to provide short acting opioid agonist tx for pts w/ #OUD was ass…

Jun 6, 2023 · 2 shares · 3,972 followers View post →
ACCP PPC PRN
@accpPPCprn · X

In a small, pilot study (n=23) a #PharmD led intervention to provide short acting opioid agonist tx for pts w/ #OUD was associated w/ ⬇️pt directed discharges (PDD) ⬆️LOS prior to PDD ⬆️MOUD initiation ⬆️naloxone rx'ing https://t.co/QIAdEiy68u

Jun 6, 2023 · 2 likes · 2 shares · 94 followers View post →
Addiction Medicine Journal Club
@AddictionMedJC · X

Episode 21 reviews an article about short-acting opioid agonists to treat opioid use disorder in the hospital @ascp_journal. Listen on any podcast app. #opioidusedisorder #AMJC #addictionmedicine #MedEd #journalclub https://t.co/4dzMbdut0U

May 31, 2023 · 1 like · 354 followers View post →
Addiction Medicine Journal Club
@AddictionMedJC · X

Ep 21 citation: Thakrar, A.P., Uritsky, T.J., Christopher, C. et al. Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder. Addict Sci Clin Pract 18, 13 (2023). @ascp_journal https://t.co/4dzMbdv0Qs

May 22, 2023 · 1 like · 354 followers View post →
Public Health at BMC
@PubHealth_BMC · X

RT @PennLDI: Short-acting opioid agonist treatment (sOAT) for opioid use disorder (OUD) is safe & effective. LDI Fellows found that sOAT:…

May 22, 2023 · 1 share · 1,561 followers View post →
Annacylostoma duodenale
@Annacylostoma · X

RT @AddictionMedJC: The next Addiction Medicine Journal Club podcast about short-acting opioid agonists for opioid use disorder in the hosp…

May 21, 2023 · 1 share · 444 followers View post →
Addiction Medicine Journal Club
@AddictionMedJC · X

The next Addiction Medicine Journal Club podcast about short-acting opioid agonists for opioid use disorder in the hospital is coming on Monday. Get the article from @ascp_journal and join the conversation. #addictionmedicine #journalclub #AMJC https://t.co/4dzMbdv0Qs

May 21, 2023 · 5 likes · 1 share · 354 followers View post →
Penn LDI
@PennLDI · X

Short-acting opioid agonist treatment (sOAT) for opioid use disorder (OUD) is safe & effective. LDI Fellows found that sOAT: ⬇️ patient directed discharges (PDDs) ⬆️ length of stay for PPDs ⬆️ rates of medication for OUD. Read more here: https://t.co/ALLbsTKSyQ

Mar 17, 2023 · 4 likes · 1 share · 8,301 followers View post →
Raagini Jawa MD, MPH, FASAM
@Raaginizzle · X

RT @pauljchristine: Love attending on inpatient addiction consult service with @BMCAddictionMed Yesterday, we discussed @especially_APT et…

Mar 3, 2023 · 3 shares · 1,536 followers View post →
Tommy Brothers
@tdbrothers · X

RT @pauljchristine: Love attending on inpatient addiction consult service with @BMCAddictionMed Yesterday, we discussed @especially_APT et…

Mar 3, 2023 · 3 shares · 3,761 followers View post →
BMC Addiction Medicine Fellowship
@BMCAddictionMed · X

RT @pauljchristine: Love attending on inpatient addiction consult service with @BMCAddictionMed Yesterday, we discussed @especially_APT et…

Mar 3, 2023 · 3 shares · 800 followers View post →
Paul Christine
@pauljchristine · X

Love attending on inpatient addiction consult service with @BMCAddictionMed Yesterday, we discussed @especially_APT et al's recent paper on the safety and preliminary efficacy of short-acting opioid use in hospitalized patients with OUD: https://t.co/e59IrWhzyG

Mar 3, 2023 · 15 likes · 3 shares · 583 followers View post →
James Hudspeth, MD, FACP
@JamesCHudspeth · X

RT @miriamh_harris: Important contribution assessing use of oxycodone & PO/IV hydromorphone for w/drawal in 23 hospitalized patients w/ OUD…

Feb 24, 2023 · 1 share · 1,363 followers View post →
Miriam Harris, MD, MSc
@miriamh_harris · X

Important contribution assessing use of oxycodone & PO/IV hydromorphone for w/drawal in 23 hospitalized patients w/ OUD 1 episode of iatrogenic intoxication Increases in MOUD & completing hospitalization More aggressive w/drawal strategies are feasible https://t.co/pCDiblAp87

Feb 24, 2023 · 2 likes · 1 share · 1,259 followers View post →