Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely winner. https://t.co/kVwig3zMaF https://t.co/tXp9TWVBwT
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.
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Feb 2023 – Apr 2023Where it's discussed
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X / Twitter66 posts
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YouTube2 videos
AI synopsis
What people are saying
The discussions predominantly reflect strong enthusiasm for the research, with comments praising the potential of neuroticism and subjective well-being polygenic scores in predicting mental disorders, exemplified by phrases like 'powerful predictor' and 'may aid early identification'. The tone is optimistic and engaged, with references to supplementary materials and the authors' contributions, showing a keen interest in the detailed scientific findings.
Most discussions appear positive, emphasizing the importance and potential of polygenic scores in predicting mental health risks.
Many posts express enthusiasm and curiosity about the research's implications, indicating high interest.
Posts include detailed mentions of specific findings, methods, and future applications, reflecting deep engagement.
The discussions highlight the significance of the research for early detection and intervention, suggesting a noteworthy impact.
Abstract in brief
- The study examined whether polygenic scores (PGSs), which measure genetic risk, can improve the prediction of major mood and psychotic disorders in people with a family history of such illnesses.
- Results showed that PGSs for neuroticism and subjective wellbeing are linked to disorder onset independently of family history, with neuroticism increasing risk and subjective wellbeing decreasing it, while PGSs for other psychiatric conditions added limited predictive value when family history was known.
- Overall, neuroticism and subjective wellbeing PGSs could help identify high-risk individuals earlier and better complement family history for mental health risk assessment.
Top posts
Most liked on X and BlueskyPolygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bipolar #psychosis https://t.co/kVwig3zMaF https://t.co/J4HTPVIZPX
As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thirds of the predictive power of family history in predicting mental illness https://t.co/kVwig3zMaF https://t.co/ECV5Nv6zaE
So excited to share our latest paper - it has been in the works since I was just a baby MSc student!
Congratulations (!!!) Drs. @RudolfUher & Martin Alda @Dal_Psychiatry whose paper on @GenomeAtlantic supported research in genetics & mental illness has been published in the American Journal of Psychiatry https://t.co/2pQPtOSWMx @GenomeCanada @HealthNS @DalMedSchool https://t.co/eeL63PkKNp
Happy to share work of our team @neuraustralia @UNSWMedicine with @RudolfUher @AlysonZwicker showing neuroticism & wellbeing PGS capture risk of new onset psychiatric disorders independent of family history & may aid early identification - online today! https://t.co/iwIDD2oGO5 https://t.co/2Kmk2Jv8AY
All mentions
Genetic Risk Factors and Prediction of Mood and Psychotic Disorders
American Journal of Psychiatry Deputy Editor Daniel S Pine discusses research on polygenic scores and their role in predicting the onset of major mood and psychotic disorders, highlighting how genetic risk measures can…
Genetic Risk Scores and Onset of Mood and Psychotic Disorders in Offspring of Affected Parents
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses the article Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents. The study shows how genetic risk…
RT @APAPubJournals: 4. “Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents,” by Alyson Zwi…
4. “Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents,” by Alyson Zwicker, Ph.D., et al. 4/4 https://t.co/HdC2cSxBK3
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents https://t.co/HdC2cSxBK3
AJP Deputy Editor Danny Pine highlights two articles from the March 2023 issue. https://t.co/Ua3jvjLzwE
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @neuraustralia: This #WorldBipolarDay we want to highlight our research lead Associate Professor @FullertonJan, who recently co-authored…
This #WorldBipolarDay we want to highlight our research lead Associate Professor @FullertonJan, who recently co-authored a paper on genetic indexes in predicting onset of major mental illness in young people.
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @AlysonZwicker: So excited to share our latest paper - it has been in the works since I was just a baby MSc student!
RT @bogglerapture: Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents https://t.co/7jNlGPa…
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents https://t.co/7jNlGPa4Xm
RT @AlysonZwicker: So excited to share our latest paper - it has been in the works since I was just a baby MSc student!
RT @RudolfUher: On predicting mental illness from polygenic scores. The best summary is in this thread by the first author Dr @AlysonZwic…
RT @RudolfUher: On predicting mental illness from polygenic scores. The best summary is in this thread by the first author Dr @AlysonZwic…
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents https://t.co/kAsclPefEi https://t.co/FtISCTVPcW
RT @RudolfUher: On predicting mental illness from polygenic scores. The best summary is in this thread by the first author Dr @AlysonZwic…
On predicting mental illness from polygenic scores. The best summary is in this thread by the first author Dr @AlysonZwicker https://t.co/1s8RpgH4Kg https://t.co/n3drXGrT5D
@OskarJefsen Well observed. There was a significant interaction between neuroticism and family history. Neuroticism PGS seems to accurately pick the onsets among those without known family history. It is in the Results section https://t.co/kVwig3zMaF
RT @RudolfUher: As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thir…
RT @RudolfUher: As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thir…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thir…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thir…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
As with most good papers, the really interesting results are in the #SupplementaryMaterial Polygenic scores carry two thirds of the predictive power of family history in predicting mental illness https://t.co/kVwig3zMaF https://t.co/ECV5Nv6zaE
Polygenic score for #neuroticism had a large sample to draw on. This may be why it powerful in predicting even sever types of mental illness. https://t.co/kVwig3zMaF https://t.co/XcYDgNhn1q
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
RT @RudolfUher: Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely w…
Which polygenic score is the best predictor of major mood and psychotic disorders in youth? #neuroticism is the unlikely winner. https://t.co/kVwig3zMaF https://t.co/tXp9TWVBwT
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents https://t.co/n8W0goymuA
RT @FullertonJan: Happy to share work of our team @neuraustralia @UNSWMedicine with @RudolfUher @AlysonZwicker showing neuroticism & wellbe…
RT @FullertonJan: Happy to share work of our team @neuraustralia @UNSWMedicine with @RudolfUher @AlysonZwicker showing neuroticism & wellbe…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @FullertonJan: Happy to share work of our team @neuraustralia @UNSWMedicine with @RudolfUher @AlysonZwicker showing neuroticism & wellbe…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
Happy to share work of our team @neuraustralia @UNSWMedicine with @RudolfUher @AlysonZwicker showing neuroticism & wellbeing PGS capture risk of new onset psychiatric disorders independent of family history & may aid early identification - online today! https://t.co/iwIDD2oGO5 https://t.co/2Kmk2Jv8AY
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @APAPubJournals: Polygenic scores for neuroticism and subjective well-being predict the risk of major mental illness independently of fa…
RT @GenomeAtlantic: Congratulations (!!!) Drs. @RudolfUher & Martin Alda @Dal_Psychiatry whose paper on @GenomeAtlantic supported research…
RT @APAPubJournals: Polygenic scores for neuroticism and subjective well-being predict the risk of major mental illness independently of fa…
RT @GenomeAtlantic: Congratulations (!!!) Drs. @RudolfUher & Martin Alda @Dal_Psychiatry whose paper on @GenomeAtlantic supported research…
Polygenic scores for neuroticism and subjective well-being predict the risk of major mental illness independently of family history. https://t.co/tiCsZvv8pc https://t.co/rKNt4cGCsP
RT @GenomeAtlantic: Congratulations (!!!) Drs. @RudolfUher & Martin Alda @Dal_Psychiatry whose paper on @GenomeAtlantic supported research…
Congratulations (!!!) Drs. @RudolfUher & Martin Alda @Dal_Psychiatry whose paper on @GenomeAtlantic supported research in genetics & mental illness has been published in the American Journal of Psychiatry https://t.co/2pQPtOSWMx @GenomeCanada @HealthNS @DalMedSchool https://t.co/eeL63PkKNp
RT @AlysonZwicker: So excited to share our latest paper - it has been in the works since I was just a baby MSc student!
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
RT @RudolfUher: Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bip…
So excited to share our latest paper - it has been in the works since I was just a baby MSc student!
Polygenic scores add to family history to better predict which young people are at risk for mental illness #depression #bipolar #psychosis https://t.co/kVwig3zMaF https://t.co/J4HTPVIZPX
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