PubHawk
March 2023 PMID 36857455

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells.

Francesco Petrelli, Valentina Scandella, Sylvie Montessuit, Nicola Zamboni, Jean-Claude Martinou, Marlen Knobloch

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172
Peak: 94 in Mar 2023
across 5 sources since May 2022

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AI synopsis

What people are saying

Several discussions highlight the exciting aspects of the publication, such as the discovery that mitochondrial pyruvate metabolism can activate dormant neural stem cells. Phrases like 'absolutely amazing' and 'critical role' indicate strong appreciation and fascination, showcasing the positive tone and context surrounding the research. Many users also emphasize the potential for developing new neuron treatments, pointing to a clear enthusiasm for the practical implications of the findings.

AgreementStrong agreement

Most discussions express strong agreement with the findings of the publication.

InterestHigh interest

Participants demonstrate high levels of curiosity and relevance regarding the study's implications.

EngagementModerate engagement

While many discussions mention the publication, the depth of engagement varies, with some users providing detailed insights.

ImpactHigh impact

A majority of contributors perceive the findings as having significant implications for neuroscience and potential therapeutic applications.

Abstract in brief

  • The study investigates the role of cellular metabolism, specifically through the mitochondrial pyruvate carrier (MPC), in the behavior of adult neural stem/progenitor cells (NSPCs) during their transition from a resting state (quiescence) to active division (proliferation).
  • It finds that quiescent NSPCs maintain active mitochondrial metabolism with high levels of MPC, which connects glycolysis to energy production in mitochondria, and that inhibiting MPC can activate these cells to differentiate into mature neurons.
  • The research suggests that understanding the metabolic pathways involving MPC could be crucial for regulating NSPC behavior and could enhance neurogenesis in the hippocampus of both adult and aged mice.
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FrezzaLab
@FrezzaLab · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 72 likes · 10 shares · 26,952 followers View post →
バイオステーション(Bio-station)/ポッドキャスト
@Bio_stations · X

ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学会ニューロナビゲータ https://t.co/m8ZLacPM2g

Mar 5, 2023 · 70 likes · 8 shares · 24,527 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

#معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى خلايا عصبية نشطة في الفئران الأمر الذي سيساعد في زيادة فرص علاج الأمراض العصبية والإعاقات العصبية إن شاء الله @Biology1802

Mar 20, 2023 · 33 likes · 11 shares · 18,874 followers View post →
Madam Mitochondria
@Madam_Mito · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://t.co/XGB0I66Zzz

Mar 2, 2023 · 28 likes · 10 shares · 10,634 followers View post →
Pan Janek
@psych_janek · X

W dorosłym mózgu istnieją komórki prekursorowe, z których rozwijają się neurony. Petrelli i wsp. właśnie pochwalili się odkryciem, jak metabolizm mitochondrium w komórce macierzystej uruchamia jej przemianę w neuron i jak tym metabolizmem sterować

Mar 7, 2023 · 12 likes · 3 shares · 306 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Martinou et al. Science Advances https://t.co/WyvxdLuBQa

Mar 1, 2023 · 11 likes · 4 shares · 507,040 followers View post →

All mentions

thmonk
@thmonk_pf · X

RT @thmonk_pf: 傍証その３ 成体神経幹細胞の静止期から増殖期への移行におけるmitochondria pyruvate代謝の役割を明らかにした mitochondria pyruvate carrioe(MPC)阻害/KDは神経幹細胞の活性化を引き起こしneuro…

Aug 19, 2024 · 1 share · 1,645 followers View post →
Bertrand de l’Isle
@Bertranddelisle · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Aug 18, 2024 · 10 shares · 738 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Aug 18, 2024 · 10 shares · 133,674 followers View post →
thmonk
@thmonk_pf · X

傍証その３ 成体神経幹細胞の静止期から増殖期への移行におけるmitochondria pyruvate代謝の役割を明らかにした mitochondria pyruvate carrioe(MPC)阻害/KDは神経幹細胞の活性化を引き起こしneuron新生を増加させた OA #pyruvate #neuron #papers https://t.co/I5rJUPBcZD https://t.co/QrC667duim

Aug 18, 2024 · 1 share · 1,645 followers View post →
T-MaX84
@max_ev_84 · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Aug 18, 2024 · 10 shares · 1,596 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Aug 18, 2024 · 10 shares · 10,634 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Feb 29, 2024 · 10 shares · 10,634 followers View post →
大隅典子
@sendaitribune · X

Today's paper at the student seminar >>> Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/oJkn9cRCUZ

Jan 16, 2024 · 1 like · 16,015 followers View post →
大隅ゼミ（東北大学）
@osumiseminar · X

【2024 1月ゼミ】 日時:1月16日(火) 19時〜 発表論文: Petrelli F, et al. Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells. Sci Adv. 2023 Mar;9(9):eadd5220. doi: 10.1126/sciadv.add5220. https://t.co/GnlSqlrWZt

Jan 10, 2024 · 1 like · 174 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://…

Dec 2, 2023 · 10 shares · 10,634 followers View post →
GemPharmatech
@GPharmatech · X

A recent study suggested that mitochondrial pyruvate metabolism is a potential target for manipulating Neural stem cell (#NSC) fate and boosting neurogenesis. Read on: https://t.co/ayfL1BvT9r #Neural #stemcells #knockout #research #biotech #innovation #technology #lifescience https://t.co/HAGZBOMH4M

Oct 9, 2023 · 250 followers View post →
GemPharmatech
@GPharmatech · X

A recent study shed light on the critical role of the mitochondrial pyruvate carrier (#MPC) in regulating #metabolic processes in adult neural stem cells (#NSCs). Read on: https://t.co/ayfL1BvT9r #neural #stemcells #research #biotech #biotechnology #innovation https://t.co/G5p8TkSSJ0

Jul 28, 2023 · 1 like · 250 followers View post →
Daya G.✨
@4evrstardancer · X

RT @renesugar: https://t.co/Zw44eQu2bZ "Pharmacological MPC inhibition increases aspartate and triggers NSPC activation."

Apr 30, 2023 · 1 share · 4,142 followers View post →
Daya G.✨
@4evrstardancer · X

RT @renesugar: https://t.co/Zw44eQu2bZ "MPC transports pyruvate into mitochondria, linking cytosolic glycolysis to mitochondrial tricarbox…

Apr 30, 2023 · 1 share · 4,142 followers View post →
Daya G.✨
@4evrstardancer · X

RT @renesugar: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/Zw44eQu2bZ

Apr 30, 2023 · 1 share · 4,142 followers View post →
Rene Sugar
@renesugar · X

https://t.co/Zw44eQu2bZ "Pharmacological MPC inhibition increases aspartate and triggers NSPC activation."

Apr 29, 2023 · 1 like · 1 share · 3,975 followers View post →
Rene Sugar
@renesugar · X

https://t.co/Zw44eQu2bZ "MPC transports pyruvate into mitochondria, linking cytosolic glycolysis to mitochondrial tricarboxylic acid cycle and oxidative phosphorylation." "We show that quiescent NSPCs have an active mitochondrial metabolism and express high levels of MPC."

Apr 29, 2023 · 1 like · 1 share · 3,975 followers View post →
Rene Sugar
@renesugar · X

https://t.co/Zw44eQu2bZ "We here show that the mitochondrial pyruvate carrier (MPC) plays a crucial and unexpected part in this process."

Apr 29, 2023 · 1 like · 3,975 followers View post →
Rene Sugar
@renesugar · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/Zw44eQu2bZ

Apr 29, 2023 · 2 likes · 1 share · 3,975 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

How to generate new neurons in the brain https://t.co/WuIweTbUy7 https://t.co/Lz5HtvUwrF https://t.co/uqgb8tBP8h

Apr 15, 2023 · 94 followers View post →
MATRIX-N Cluster UBC
@MatrixN_UBC · X

https://t.co/NNjKdTIcqc

Apr 4, 2023 · 211 followers View post →
أمـــل| Amal
@Amal_FA11 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 30, 2023 · 11 shares · 496 followers View post →
Science above the clouds
@pillolescienza · X

Waking up dormant brain stem cells to create new neurons. https://t.co/62jcoGDSv6

Mar 21, 2023 · 34 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 21, 2023 · 11 shares · 18,874 followers View post →
Eiman A Al-Shami
@geologyteacher · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 2,949 followers View post →
Sattam Almalki
@sattam9974 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 3,883 followers View post →
Basim Al Gashgari
@basimbyg2 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 24,642 followers View post →
Safaa A.O. Fallatah
@fallatahsafaa · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 929 followers View post →
Dr. Amany
@AmanyALqosaibi · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 1,826 followers View post →
riyad3eban
@riyad3eban · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 559 followers View post →
Hajar
@TaibiHajar1 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 50 followers View post →
ملتقى علوم الاحياء
@Biology1802 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى…

Mar 20, 2023 · 11 shares · 54,682 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

#معلومة_تهم_الباحثين... علماء #الأحياء_الجزيئية و #الكيمياء الحيوية يكتشفون دور مادةالباروفيت في تطور الخلايا الجذعية إلى خلايا عصبية نشطة في الفئران الأمر الذي سيساعد في زيادة فرص علاج الأمراض العصبية والإعاقات العصبية إن شاء الله @Biology1802

Mar 20, 2023 · 33 likes · 11 shares · 18,874 followers View post →
Dnyanesh Dubal
@dddnyanesh228 · X

RT @KnoblochLab: https://t.co/c2ATbUSbqM Should we revisit the metabolic state of quiescence in adult neural stem cells? Excited that our…

Mar 20, 2023 · 7 shares · 50 followers View post →
Katia Maalouf, PhD
@KatiaMaalouf · X

The field of neurodegenerative diseases is heading to a bright future! Scientists have figured out a way to activate the formation of new neurons from neural stem cells in the brain. https://t.co/3bdPBU1v93

Mar 19, 2023 · 5 likes · 1 share · 107 followers View post →
Oskar
@onespacez · X

Absolutely amazing stuff. https://t.co/0eBfrsidPO

Mar 15, 2023 · 32 followers View post →
mom
@mom_neurosci · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 14, 2023 · 8 shares · 805 followers View post →
Rina Saltman
@rinatie_ceo · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/5cOUddSbaJ

Mar 13, 2023 · 3,563 followers View post →
Masa Yamamoto予測誤差が大きい人生を楽しもう
@mshero_y · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 13, 2023 · 8 shares · 1,064 followers View post →
稲田のりこ
@noriko_inada · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 13, 2023 · 8 shares · 2,219 followers View post →
山形方人(nihonGO)
@yamagatm3 · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 13, 2023 · 8 shares · 11,134 followers View post →
S.HIROMITSU
@S_HIROMI2 · X

神経幹/前駆細胞(NSPCs)は通常,休眠状態で分化も増殖もしないが特定の刺激でonになり増殖と分化を始める. この研究の結果,薬剤やKOによるピルビン酸輸送の阻害により,NSPCsはOXPHOS->解糖と代謝がスイッチし,増殖と分化が始まる事が分かった. 代謝の向きが逆っぽいが違わない. https://t.co/0RF96hQt3E

Mar 12, 2023 · 42 followers View post →
Miguel Ángel Sogorb
@MASogorb · X

Descubren cómo hacer que se generen nuevas neuronas en un cerebro adulto https://t.co/tQtP2sC0En Más información: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/O0VitnFIDt

Mar 11, 2023 · 157 followers View post →
Scotty Dolan
@ScottyDolan2 · X

@hubermanlab Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/AAUXwPBnzZ

Mar 10, 2023 View post →
Reddit Journal of Science
@rsciencejournal · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells (Mar 2023) https://t.co/Fip0oFSffK #science #biology #pyruvate #metabolism #activation #adult

Mar 10, 2023 · 336 followers View post →
Billi Lab
@BilliUCLALab · X

A team of biologists has discovered how to awaken neural stem cells and reactivate them in adult mice. https://t.co/43JosvvTfI

Mar 10, 2023 · 61 followers View post →
Cortex Mag
@MagCortex · X

"Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells", l'article paru dans ScienceAdvances https://t.co/z0YrvykvUu

Mar 10, 2023 · 1 like · 1,114 followers View post →
Simon Achi Omerigwe
@OmerigweSA · X

Scientists Discover How To Generate New Neurons in the Adult Brain. https://t.co/VAMdCBn9qU Have a good read!

Mar 9, 2023 · 126 followers View post →
julia
@im_niallsexual · X

RT @psych_janek: W dorosłym mózgu istnieją komórki prekursorowe, z których rozwijają się neurony. Petrelli i wsp. właśnie pochwalili się od…

Mar 9, 2023 · 3 shares · 349 followers View post →
World Stem Cell Summit
@WSCSummit · X

Research: Biologists discover how to awaken and reactivate neural stem cells. https://t.co/Yoon8lPvCO #brain #stemcells #regenerativemedicine #biotech #science

Mar 9, 2023 · 12,174 followers View post →
Abdullah Atif
@atifabdullah79 · X

https://t.co/TcZSCXLEOX

Mar 8, 2023 · 3 followers View post →
James Keim
@JamesKeim8 · X

Generating new neurons in the adult brain! https://t.co/XNSPZKcgKP

Mar 8, 2023 · 541 followers View post →
ifo
@SniezekOZZP · X

RT @psych_janek: W dorosłym mózgu istnieją komórki prekursorowe, z których rozwijają się neurony. Petrelli i wsp. właśnie pochwalili się od…

Mar 8, 2023 · 3 shares · 192 followers View post →
Sreenivasa Raghavan
@SreenivasaRS · X

RT @AusStemCell: 'A team of biologists led by @unige_en and @unil has discovered how to awaken neural stem cells and reactivate them in adu…

Mar 8, 2023 · 1 share · 52 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

https://t.co/ZCCKlcKviI

Mar 8, 2023 · 78 followers View post →
Stem Cell Foundation
@AusStemCell · X

'A team of biologists led by @unige_en and @unil has discovered how to awaken neural stem cells and reactivate them in adult mice.' Read more: https://t.co/OMbkckMwWp Paper: https://t.co/6xoQXccHMa https://t.co/6t8cLt6Y79

Mar 7, 2023 · 1 like · 1 share · 14,852 followers View post →
Researching the Brain
@Brain_Database · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells #brain https://t.co/5YpYTzsbGT

Mar 7, 2023 · 1,037 followers View post →
Aleksander Waś
@aleksander_was · X

RT @psych_janek: W dorosłym mózgu istnieją komórki prekursorowe, z których rozwijają się neurony. Petrelli i wsp. właśnie pochwalili się od…

Mar 7, 2023 · 3 shares · 364 followers View post →
DSB UNIL
@SocialDSB_UNIL · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells. https://t.co/7fb1MHL4tf #UNIL #FBM #DSB @KnoblochLab

Mar 7, 2023 · 1 like · 135 followers View post →
Amilcar Ruggerri
@ARuggerri · X

A team led by scientists from the Universities of Geneva (UNIGE) and Lausanne (UNIL) has discovered the importance of cell metabolism in this process and identified how to wake up these neural stem cells and reactivate them. https://t.co/Bgf0yipSTa

Mar 7, 2023 · 36 followers View post →
KSFAN
@KSFAN1 · X

在這一過程中的重要性，並確定了「如何喚醒這些神經幹細胞並重新啟動它們」。在科學家的努力下，成年甚至老年小鼠大腦中的新神經元數量成功增加。 這篇題為 "Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells" 的論文

Mar 7, 2023 · 6,434 followers View post →
Pan Janek
@psych_janek · X

W dorosłym mózgu istnieją komórki prekursorowe, z których rozwijają się neurony. Petrelli i wsp. właśnie pochwalili się odkryciem, jak metabolizm mitochondrium w komórce macierzystej uruchamia jej przemianę w neuron i jak tym metabolizmem sterować

Mar 7, 2023 · 12 likes · 3 shares · 306 followers View post →
charlesazorn
@charlesazorn · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/FmSW4z5ueg

Mar 7, 2023 · 2 likes · 1,608 followers View post →
Brain
@SatoshiParkin · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 6, 2023 · 8 shares · 22 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells @KnoblochLab https://t.co/…

Mar 6, 2023 · 1 share · 132 followers View post →
Agingdoc
@agingdoc1 · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells @KnoblochLab https://t.co/bOwST9Rf5b https://t.co/1sGTMYSngV

Mar 6, 2023 · 5 likes · 1 share · 42,377 followers View post →
Martin Duenas
@duenasm85 · X

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. These findings highlight the importance of metabolism for neural stem/progenitor cell (NSPC) re…https://t.co/DlzBufapke https://t.co/SudL24MP8Q

Mar 6, 2023 · 80 followers View post →
SATOX2020
@satox218news · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 6, 2023 · 8 shares · 308 followers View post →
MedicalMarvels
@YMedicalmarvels · X

Scientists have figured out how to reactivate neurons growth in the brain https://t.co/ohrjZkJT7B

Mar 6, 2023 · 491 followers View post →
さすらいの研究者（さすせん）
@PI_in_abroad · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 6, 2023 · 8 shares · 7,066 followers View post →
SNZK
@shinopp · X

RT @Bio_stations: ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学…

Mar 5, 2023 · 8 shares · 723 followers View post →
バイオステーション(Bio-station)/ポッドキャスト
@Bio_stations · X

ミトコンドリアと神経幹細胞の活性化 静止期の神経幹細胞ではミトコン代謝が活発らしい。特にピルビン酸輸送因子が高く発現していて、これを阻害すると神経幹細胞の活性化が起きるらしい すこし直感とは違っておもろい。メカも気になる #日本神経科学学会ニューロナビゲータ https://t.co/m8ZLacPM2g

Mar 5, 2023 · 70 likes · 8 shares · 24,527 followers View post →
Alex Gould Lab, now only @alexgouldlab.bsky.social
@AlexGouldLab · X

RT @KnoblochLab: https://t.co/c2ATbUSbqM Should we revisit the metabolic state of quiescence in adult neural stem cells? Excited that our…

Mar 5, 2023 · 7 shares · 1,201 followers View post →
Longevity
@LongevityTao · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://t.co/9asfAE7bxQ

Mar 4, 2023 · 331 followers View post →
Jessica Perego
@PeregoJessica · X

RT @Pluchinolab: Nice one @KnoblochLab | https://t.co/oSm8kDJt2o

Mar 3, 2023 · 2 shares · 124 followers View post →
Ariakas Enoreth
@Aenoreth · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/H1wPnVmP0O

Mar 3, 2023 · 1 like · 1,005 followers View post →
Gircor, recherche animale et alternatives
@GIRCOR · X

Mar 3, 2023 · 3,948 followers View post →
Frank Lin
@FrankHaopeng · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 3, 2023 · 10 shares · 64 followers View post →
Ana Delgado
@anad23 · X

RT @KnoblochLab: https://t.co/c2ATbUSbqM Should we revisit the metabolic state of quiescence in adult neural stem cells? Excited that our…

Mar 3, 2023 · 7 shares · 49 followers View post →
thmonk
@thmonk_pf · X

RT @thmonk_pf: 成体神経幹細胞/前駆細胞（NSPC）の静止➡増殖のswitchはミトコンドリアピルビン酸輸送体（MPC）の抑制である 静止期NSPCが活発なミトコンドリア代謝を持ちMPCを高レベルで発現 薬理学的なMPC阻害、Mpc1の遺伝子抑制どちらも神経新…

Mar 2, 2023 · 2 shares · 1,645 followers View post →
Jose Hernandez
@Pharma_Mty · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 194 followers View post →
Mitrix Bio
@PathfinderEq · X

RT @philosophising4: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances htt…

Mar 2, 2023 · 10 shares · 4,884 followers View post →
Reddit Journal of Science
@rsciencejournal · X

1/ How to awaken neural stem cells and reactivate them in adult mice: Biologists succeeded in increasing the number of new neurons in the brain of adult and even elderly mice. These results could be promising for the treatment of https://t.co/s8pw2m2aqu

Mar 2, 2023 · 336 followers View post →
Sean Luke De Silva
@seanlukestar · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 288 followers View post →
Sean Luke De Silva
@seanlukestar · X

RT @Pluchinolab: Nice one @KnoblochLab | https://t.co/oSm8kDJt2o

Mar 2, 2023 · 2 shares · 288 followers View post →
Takashi Namba
@takashi_namba · X

RT @KnoblochLab: https://t.co/c2ATbUSbqM Should we revisit the metabolic state of quiescence in adult neural stem cells? Excited that our…

Mar 2, 2023 · 7 shares · 362 followers View post →
Ankit Singla
@In_AnkitSingla · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 1,484 followers View post →
Lina Ruiz
@LinaRuizH · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/MohNj31ULM https://t.co/ZhgduajneJ

Mar 2, 2023 · 127 followers View post →
マイトファジー(Mitophagy)論文紹介
@Mitophagy_Res · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells. ミトコンドリアのピルビン酸代謝は、静止期成体神経幹細胞の活性化を制御する。 Sci Adv. 2023 PMID: 36857455 https://t.co/9keZsJXqHL

Mar 2, 2023 · 128 followers View post →
HEM News Agency
@halfeatenmind · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/qScHTVqtSp

Mar 2, 2023 · 4,143 followers View post →
anirudh
@AniRude95 · X

RT @KnoblochLab: https://t.co/c2ATbUSbqM Should we revisit the metabolic state of quiescence in adult neural stem cells? Excited that our…

Mar 2, 2023 · 7 shares · 484 followers View post →
D. Parker Kelley
@sequencemyneuro · X

RT @philosophising4: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances htt…

Mar 2, 2023 · 10 shares · 772 followers View post →
Mitochondrial Medicine
@Mito_Therapy · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 7,228 followers View post →
乙です〜
@deep__wreck · X

RT @thmonk_pf: 成体神経幹細胞/前駆細胞（NSPC）の静止➡増殖のswitchはミトコンドリアピルビン酸輸送体（MPC）の抑制である 静止期NSPCが活発なミトコンドリア代謝を持ちMPCを高レベルで発現 薬理学的なMPC阻害、Mpc1の遺伝子抑制どちらも神経新…

Mar 2, 2023 · 2 shares · 1,992 followers View post →
thmonk
@thmonk_pf · X

成体神経幹細胞/前駆細胞（NSPC）の静止➡増殖のswitchはミトコンドリアピルビン酸輸送体（MPC）の抑制である 静止期NSPCが活発なミトコンドリア代謝を持ちMPCを高レベルで発現 薬理学的なMPC阻害、Mpc1の遺伝子抑制どちらも神経新生を促進 Open Access #NSPC #papers https://t.co/8CoLhTtbbO https://t.co/V1X2YkNswe

Mar 2, 2023 · 4 likes · 2 shares · 1,645 followers View post →
Gun Kim
@KvChannels · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 5 followers View post →
Gilles Gouspillou
@GGouspillou · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 1,855 followers View post →
Dr Alexandra Harvey
@tealgecko · X

RT @FrezzaLab: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 10 shares · 282 followers View post →
Adri
@atri2adrian · X

RT @philosophising4: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances htt…

Mar 2, 2023 · 10 shares · 68 followers View post →
Madam Mitochondria
@Madam_Mito · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://t.co/XGB0I66Zzz

Mar 2, 2023 · 28 likes · 10 shares · 10,634 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Nice one @KnoblochLab | https://t.co/oSm8kDJt2o

Mar 2, 2023 · 3 likes · 2 shares · 4,767 followers View post →
FrezzaLab
@FrezzaLab · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/zjMHZZ1uZb

Mar 2, 2023 · 72 likes · 10 shares · 26,952 followers View post →
MPC Therapeutics
@MpcTherapeutics · X

#justout: Our CSO's latest article in @ScienceAdvances : "Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells." #MPC #mitochondria #StemCells -> https://t.co/67tZWqQpQG https://t.co/STWIRae3yC

Mar 2, 2023 · 2 likes · 41 followers View post →
beppedeleonardis
@bedel1945 · X

I biologi scoprono come creare i neuroni Gli scienziati sono riusciti a risvegliare cellule dormienti in grado di rigenerare il nostro cervello, Una speranza futura per il trattamento delle malattie neurodegenerative. https://t.co/wMovAoR2Lr

Mar 2, 2023 · 1 like · 1,350 followers View post →
LibertyTakes
@StenzelHealth · X

RT @NeuroscienceNew: “Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Marti…

Mar 1, 2023 · 4 shares · 11 followers View post →
Helen Martirosova,PhD, MSc
@HMartirosova · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/x0vmtBF7bc

Mar 1, 2023 · 85 followers View post →
Ordo Fraterna Fibonacci
@OrdoFibonacci · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://t.co/UmKjujMfn2

Mar 1, 2023 · 2,567 followers View post →
MITO-GARAGE
@MITO_GARAGE · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/xduqFoCyI8

Mar 1, 2023 · 54 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/2tKw6axrPY https://t.co/04aGCm0awf

Mar 1, 2023 · 24,131 followers View post →
Lance Fogan
@lance_fogan · X

RT @NeuroscienceNew: “Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Marti…

Mar 1, 2023 · 4 shares · 7,649 followers View post →
☆°Kharnivore°☆
@Kharnivore_Dux · X

RT @NeuroscienceNew: “Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Marti…

Mar 1, 2023 · 4 shares · 185 followers View post →
Lucky Mendez
@lucky_mendez3 · X

RT @NeuroscienceNew: “Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Marti…

Mar 1, 2023 · 4 shares · 318 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells” by Jean-Claude Martinou et al. Science Advances https://t.co/WyvxdLuBQa

Mar 1, 2023 · 11 likes · 4 shares · 507,040 followers View post →
Dr Anthony Martin
@AMAinsight · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | Science Advances https://t.co/s4tnte912L

Mar 1, 2023 · 914 followers View post →
PromisingPreprints
@PromPreprint · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/kEjoGh2Fjh

Jun 22, 2022 · 3,304 followers View post →
Franco Cavezzali
@FranCave2001 · X

RT @biorxivpreprint: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/07jXivQc…

Jun 1, 2022 · 4 shares · 128 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells | bioRxiv https://t.co/H6WFTXcoNt

Jun 1, 2022 · 5 likes · 4,767 followers View post →
Zero One
@ZeroOne33408052 · X

RT @biorxivpreprint: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/07jXivQc…

May 31, 2022 · 4 shares · 2,364 followers View post →
Ankit Singla
@In_AnkitSingla · X

RT @biorxivpreprint: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/07jXivQc…

May 31, 2022 · 4 shares · 1,484 followers View post →
bioRxiv Cell Biology
@biorxiv_cellbio · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/TyTvPSP5B4 #biorxiv_cellbio

May 31, 2022 · 1 share · 7,706 followers View post →
bioRxiv
@biorxivpreprint · X

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells https://t.co/07jXivQchu #bioRxiv

May 31, 2022 · 8 likes · 4 shares · 137,865 followers View post →