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Nat Commun March 2023 PMID 36859400

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST.

Yahui Long, Kok Siong Ang, Mengwei Li, Kian Long Kelvin Chong, Raman Sethi, Chengwei Zhong, Hang Xu, Zhiwei Ong, Karishma Sachaphibulkij, Ao Chen, Li Zeng, Huazhu Fu, Min Wu, Lina Hsiu Kim Lim, Longqi Liu

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Mentions

33
Peak: 23 in Mar 2023
across 4 sources since Jan 2023

Extended reach

37,966
potential audience

Total likes

81

Video views

39

Mentions per month

Jan 2023 – Apr 2024

Where it's discussed

  • X / Twitter27 posts
  • Blogs3 articles
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone is optimistic, with posts mentioning the paper as a 'game changer' and highlighting improvements like '10% higher accuracy' and detailed tissue structures. Words like 'just published,' 'new results,' and hashtags related to bioinformatics suggest excitement and anticipation, reflecting their perception of significant impact and high interest in the research's implications.

AgreementModerate agreement

Most discussions support and promote the significance of GraphST, emphasizing its advancements and potential.

InterestHigh interest

Social discussions reflect high curiosity and enthusiasm, often highlighting new results and applications.

EngagementModerate engagement

Participants share positive comments, mention figures and methods, and express support, indicating moderate but meaningful engagement.

ImpactModerate impact

There’s recognition that this work advances spatial transcriptomics analysis, suggesting potential for substantial influence in bioinformatics and biomedical research.

Abstract in brief

  • GraphST is a new method that uses graph neural networks and contrastive learning to analyze spatial transcriptomics data, helping identify spatial patterns in gene expression.
  • It outperforms existing methods by providing 10% higher accuracy in clustering tissues, accurately revealing detailed tissue structures in brain and embryo samples, and allowing joint analysis of multiple tissue slices.
  • Additionally, GraphST effectively deconvolves cell types within tissues, capturing important spatial niches like lymph node germinal centers and exhausted T cells in breast tumors.]
Read the full abstract

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BioDecoded
@BioDecoded · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communications https://t.co/zvqFgrwLlK #Bioinformatics https://t.co/5xGQPKvvT3

Mar 13, 2023 · 47 likes · 12 shares · 8,900 followers View post →
Javier Santoyo
@jsantoyo · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST. #SpatialTranscriptomics @NatureComms https://t.co/7fY8loYjqL

Mar 18, 2023 · 11 likes · 2 shares · 6,100 followers View post →
Long Yahui
@long_yahui · X

Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just online in Nature Communications. https://t.co/8ins4rgijm https://t.co/Qn9vYPLcP5

Mar 1, 2023 · 9 likes · 5 shares · 16 followers View post →
Paul Lopez
@lopezunwired · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST https://t.co/4zQy8ZEwiY #MachineLearning #NatureJournal #AI https://t.co/CaUhj3MrvF

Mar 1, 2023 · 5 likes · 2,483 followers View post →
SeqComplete
@SeqComplete · X

#BioIT #BioInformatics Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST [NEW RESULTS] https://t.co/9G0ygXf7o7

Jan 5, 2023 · 2 likes · 1 share · 4,411 followers View post →
Reluctant Quant
@DrMattCrowson · X

RT Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST https://t.co/A5uHapBOln https://t.co/lNPVdhPhlf

Mar 1, 2023 · 2 likes · 1,261 followers View post →

All mentions

Singapore Immunology Network
@astar_SIgN · X

(3) Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST Yahui L., Kok Siong A., Mengwei L., Kelvin C., Raman S., Chengwei Z., Xu H., Jinmiao C. https://t.co/6j30UYefij

Apr 19, 2024 · 2 likes · 406 followers View post →
Jinmiao Chen Lab
@CJM_lab · X

RT @long_yahui: Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just…

May 11, 2023 · 5 shares · 286 followers View post →
ddhb
@ddhb80180543 · X

RT @jsantoyo: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST. #SpatialTranscriptomic…

Mar 18, 2023 · 2 shares · 15 followers View post →
genomicspark
@hexomics · X

RT @jsantoyo: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST. #SpatialTranscriptomic…

Mar 18, 2023 · 2 shares · 91 followers View post →
Javier Santoyo
@jsantoyo · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST. #SpatialTranscriptomics @NatureComms https://t.co/7fY8loYjqL

Mar 18, 2023 · 11 likes · 2 shares · 6,100 followers View post →
Bodhi Dharma
@dharma92biol · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 14, 2023 · 12 shares · 166 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 14, 2023 · 12 shares · 768 followers View post →
Sherri Y Sorkhabi
@SYSorkhabi · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 14, 2023 · 12 shares · 1,470 followers View post →
sunshine
@sunshin21502307 · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 14, 2023 · 12 shares · 27 followers View post →
Taimur Khan
@Taimur0321 · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 14, 2023 · 12 shares · 19 followers View post →
Huazhu FU
@Hz_MedAI · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 13, 2023 · 12 shares · 776 followers View post →
Olha Ivashkiv
@olhaivashkiv · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communications https://t.co/z4C4sr7FBl

Mar 13, 2023 · 1 like · 186 followers View post →
Dr Ayala
@DrKykeQro · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 13, 2023 · 12 shares · 453 followers View post →
AiiHC International Ltd.
@AiihcLtd2022 · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 13, 2023 · 12 shares · 819 followers View post →
Fábio Fonseca
@FbioFon84085623 · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 13, 2023 · 12 shares · 580 followers View post →
CompChemBio Bot
@CompChemBioBot · X

RT @BioDecoded: Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communicatio…

Mar 13, 2023 · 12 shares · 2,761 followers View post →
BioDecoded
@BioDecoded · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST | Nature Communications https://t.co/zvqFgrwLlK #Bioinformatics https://t.co/5xGQPKvvT3

Mar 13, 2023 · 47 likes · 12 shares · 8,900 followers View post →
Transcriptomes
@transcriptomes · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with... https://t.co/IsoXDOHREB

Mar 2, 2023 · 1,809 followers View post →
Raman Sethi
@raman4391 · X

RT @AndyLYHLYH: Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just…

Mar 1, 2023 · 5 shares · 49 followers View post →
Huazhu FU
@Hz_MedAI · X

RT @AndyLYHLYH: Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just…

Mar 1, 2023 · 5 shares · 776 followers View post →
Mengwei Li
@mengweili9 · X

RT @AndyLYHLYH: Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just…

Mar 1, 2023 · 5 shares · 33 followers View post →
DISCO
@HSCRM2 · X

RT @AndyLYHLYH: Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just…

Mar 1, 2023 · 5 shares · 165 followers View post →
Long Yahui
@long_yahui · X

Our paper 'Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST' was just online in Nature Communications. https://t.co/8ins4rgijm https://t.co/Qn9vYPLcP5

Mar 1, 2023 · 9 likes · 5 shares · 16 followers View post →
Paul Lopez
@lopezunwired · X

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST https://t.co/4zQy8ZEwiY #MachineLearning #NatureJournal #AI https://t.co/CaUhj3MrvF

Mar 1, 2023 · 5 likes · 2,483 followers View post →
Reluctant Quant
@DrMattCrowson · X

RT Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST https://t.co/A5uHapBOln https://t.co/lNPVdhPhlf

Mar 1, 2023 · 2 likes · 1,261 followers View post →
CompChemBio Bot
@CompChemBioBot · X

RT @SeqComplete: #BioIT #BioInformatics Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with Graph…

Jan 5, 2023 · 1 share · 2,761 followers View post →
SeqComplete
@SeqComplete · X

#BioIT #BioInformatics Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST [NEW RESULTS] https://t.co/9G0ygXf7o7

Jan 5, 2023 · 2 likes · 1 share · 4,411 followers View post →