Microb Biotechnol June 2023 PMID 36860178

Rewiring the respiratory pathway of Lactococcus lactis to enhance extracellular electron transfer.

Liuyan Gu, Xinxin Xiao, Ge Zhao, Paul Kempen, Shuangqing Zhao, Jianming Liu, Sang Yup Lee, Christian Solem

Mentions

5
Peak: 2 in Mar 2023
across 2 sources since Mar 2023

Extended reach

4,709
potential audience

Total likes

15

Video views

48

Mentions per month

Mar 2023 – Aug 2023

Where it's discussed

  • X / Twitter4 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight key aspects like the use of Lactococcus lactis to reduce oxidative stress and the potential for improved fermentation processes, with phrases such as 'introducing artificial mediator' and 'next step is electro-fermentation' emphasizing ongoing interest and perceived future impact. The tone is enthusiastic and forward-looking, demonstrating curiosity and acknowledgment of the study's significance.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some expressing enthusiasm about its potential applications.

InterestHigh interest

The topics of oxidative stress, extracellular electron transfer, and fermentation are highly relevant and intriguing to the audience.

EngagementModerate engagement

Comments include references to specific methods and potential future developments, indicating thoughtful engagement.

ImpactModerate impact

Participants recognize that the research could influence biotechnological methods and microbiome engineering, though some see it as an early step.

Abstract in brief

  • The study demonstrates that Lactococcus lactis, a bacteria typically known for fermentation, can use ferricyanide as an alternative electron acceptor to support growth, especially when its NAD regeneration is blocked, indicating a new pathway for extracellular electron transfer (EET).
  • The researchers identified key components like NADH dehydrogenase and 2-amino-3-carboxy-1,4-naphthoquinone as essential for EET and found that traditional respiration pathways influence factors such as cell shape and acid resistance, with modifications leading to enhanced EET capacity.
  • Using adaptive laboratory evolution and genome sequencing, they enhanced EET in L. lactis by disrupting menaquinone biosynthesis, which has potential applications in food fermentation, microbiome engineering, and reducing oxidative stress in microbial communities.]

Top posts

Most liked on X and Bluesky
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

Did you know that Lactococcus lactis can use oxygen to reduce oxidative stress? Check out Gu and coworkers' latest research on the molecular mechanisms behind this surprising finding!!! #Lactococcus, #probiotics, #fermentation. Read here

Apr 6, 2023 · 12 likes · 2 shares · 2,509 followers View post →
Xinxin Xiao
@Xinxin_Xiao1989 · X

Glad to contribute a nice study led by DTU Food introducing artificial mediator to enhance extracellular electron transfer of Lactococcus lactis, for improved anaerobic fermentation https://t.co/14gtvty2uu Next step is believed to be electro-fermentation https://t.co/uSU1iQgonT

Mar 2, 2023 · 3 likes · 507 followers View post →
Kenneth Timmis
@KennethTimmis · X

Rewiring the respiratory pathway of Lactococcus lactis to enhance extracellular electron transfer https://t.co/SX4wQ81It3

Mar 5, 2023 · 1,234 followers View post →
juan luis ramos
@ramoslabgranada · X

RT @MicrobialBiote1: Did you know that Lactococcus lactis can use oxygen to reduce oxidative stress? Check out Gu and coworkers' latest res…

Apr 6, 2023 · 2 shares · 403 followers View post →

All mentions

juan luis ramos
@ramoslabgranada · X

RT @MicrobialBiote1: Did you know that Lactococcus lactis can use oxygen to reduce oxidative stress? Check out Gu and coworkers' latest res…

Apr 6, 2023 · 2 shares · 403 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

Did you know that Lactococcus lactis can use oxygen to reduce oxidative stress? Check out Gu and coworkers' latest research on the molecular mechanisms behind this surprising finding!!! #Lactococcus, #probiotics, #fermentation. Read here

Apr 6, 2023 · 12 likes · 2 shares · 2,509 followers View post →
Kenneth Timmis
@KennethTimmis · X

Rewiring the respiratory pathway of Lactococcus lactis to enhance extracellular electron transfer https://t.co/SX4wQ81It3

Mar 5, 2023 · 1,234 followers View post →
Xinxin Xiao
@Xinxin_Xiao1989 · X

Glad to contribute a nice study led by DTU Food introducing artificial mediator to enhance extracellular electron transfer of Lactococcus lactis, for improved anaerobic fermentation https://t.co/14gtvty2uu Next step is believed to be electro-fermentation https://t.co/uSU1iQgonT

Mar 2, 2023 · 3 likes · 507 followers View post →