Nat Aging February 2023 PMID 36873708

Optogenetic rejuvenation of mitochondrial membrane potential extends lifespan.

Brandon J Berry, Anežka Vodičková, Annika Müller-Eigner, Chen Meng, Christina Ludwig, Matt Kaeberlein, Shahaf Peleg, Andrew P Wojtovich

Mentions

62
Peak: 7 in Feb 2023
across 6 sources since Jan 2023

Extended reach

73,676
potential audience

Total likes

681

Video views

23,943

Mentions per month

Jan 2023 – Feb 2024

Where it's discussed

  • News35 articles
  • X / Twitter11 posts
  • Blogs8 articles
  • Reddit4 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The social discussions show enthusiasm for the study’s potential, with posts emphasizing the importance of maintaining mitochondrial function in aging, illustrated by comments like 'opposing age-related decline' and 'extends lifespan.' The tone varies from supportive and excited to cautiously optimistic, reflecting both interest and engagement with the topic's significance.

AgreementModerate agreement

Most discussions acknowledge the significance of the research findings, especially highlighting the potential to extend lifespan and improve health in aging organisms, showing general support for the article's conclusions.

InterestHigh interest

Comments reveal high interest, with many expressing excitement about the innovative use of optogenetics and its implications for aging and health, using phrases like 'revolutionary' and 'game-changing'.

EngagementHigh engagement

Several participants delve into detailed explanations of mitochondrial functions, aging processes, and the methods used, indicating deep engagement with the study's content.

ImpactModerate impact

Discussions suggest that this research could influence future studies on aging and potential therapies, although some posts remain optimistic but cautious about real-world applications.

Abstract in brief

  • The study demonstrates that using optogenetics to activate a light-sensitive proton pump can increase mitochondrial membrane potential in adult organisms.
  • This increase in mitochondrial function helps improve age-related health problems and can even extend lifespan.
  • The results suggest that maintaining mitochondrial membrane potential is crucial for slowing aging and promoting longer, healthier lives.]

Top posts

Most liked on X and Bluesky
Nature Aging
@NatureAging · X

In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #healthspan and #lifespan in C. elegans => Mitochondrial charge = key regulator of biological aging @mitobrandon @UWMedicine @URNeuroscience https://t.co/mkBeyI0b3j

Feb 22, 2023 · 25 likes · 7 shares · 18,760 followers View post →
Andreea Nitescu RD MSc
@AndreeaNRD · X

And "Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan"

May 6, 2023 · 4 likes · 1 share · 1,301 followers View post →
サイエンスあれこれ
@sarekore · X

したところ、線虫の寿命が30 ~ 40% 伸びました。この結果は、歳を取っても機能不全にならないミトコンドリアの可能性を示唆します。Nature Aging誌https://t.co/K2hH6cNcgV

Jan 3, 2023 · 2 likes · 923 followers View post →
BillOckham
@BillOccham0 · X

Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan - PubMed ⁦@agingdoc1⁩ ⁦@AgingBiology⁩ https://t.co/RxYI7dEdXe

Apr 2, 2023 · 1 like · 583 followers View post →
European Journal of Neuroscience
@EJNeuroscience · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 22, 2023 · 7 shares · 22,944 followers View post →
Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
@Alexis_Lomakin · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 22, 2023 · 7 shares · 3,651 followers View post →

All mentions

らくろわ
@raqrowa · X

@yosshy666 @araya0321 ミトコンドリアDNAを編集して光合成する研究、ありますねぇ! 置いときます https://t.co/eCccAgAcpG

Feb 4, 2024 · 160 followers View post →
Andreea Nitescu RD MSc
@AndreeaNRD · X

And "Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan"

May 6, 2023 · 4 likes · 1 share · 1,301 followers View post →
BillOckham
@BillOccham0 · X

Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan - PubMed ⁦@agingdoc1⁩ ⁦@AgingBiology⁩ https://t.co/RxYI7dEdXe

Apr 2, 2023 · 1 like · 583 followers View post →
Vaibhav Tiwary
@vt_tiwary · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 23, 2023 · 7 shares · 296 followers View post →
BGille
@BenetotheG · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 23, 2023 · 7 shares · 25 followers View post →
FilomeniLab
@FilomeniL · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 23, 2023 · 7 shares · 107 followers View post →
Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
@Alexis_Lomakin · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 22, 2023 · 7 shares · 3,651 followers View post →
Surojit Sural
@surojitsural · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 22, 2023 · 7 shares · 883 followers View post →
European Journal of Neuroscience
@EJNeuroscience · X

RT @NatureAging: In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #health…

Feb 22, 2023 · 7 shares · 22,944 followers View post →
Nature Aging
@NatureAging · X

In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #healthspan and #lifespan in C. elegans => Mitochondrial charge = key regulator of biological aging @mitobrandon @UWMedicine @URNeuroscience https://t.co/mkBeyI0b3j

Feb 22, 2023 · 25 likes · 7 shares · 18,760 followers View post →
サイエンスあれこれ
@sarekore · X

したところ、線虫の寿命が30 ~ 40% 伸びました。この結果は、歳を取っても機能不全にならないミトコンドリアの可能性を示唆します。Nature Aging誌https://t.co/K2hH6cNcgV

Jan 3, 2023 · 2 likes · 923 followers View post →