PLoS Comput Biol March 2023 PMID 36877736

CustOmics: A versatile deep-learning based strategy for multi-omics integration.

Hakim Benkirane, Yoann Pradat, Stefan Michiels, Paul-Henry Cournède

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Peak: 15 in Mar 2023

across 2 sources since Sep 2022

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Sep 2022 – Jun 2023

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What people are saying

The overall digital discussions reflect a strong interest in the technical innovation and applications of CustOmics, exemplified by comments highlighting the use of deep-learning strategies, interpretability features, and implications for cancer research. The tone varies from admiration to cautious optimism, with some participants referencing specific techniques like Shapley explanations and discussing the potential of the approach to advance multi-omics integration challenging traditional methods.

AgreementModerate agreement

Most discussions acknowledge the significance of the CustOmics approach, viewing it as a valuable contribution to multi-omics integration, although some are cautious about its novelty.

InterestHigh interest

The posts demonstrate high interest, with frequent mentions of deep learning, multi-omics, and potential applications in biological research, indicating a keen engagement with the topic.

EngagementModerate engagement

Posts reference technical aspects such as the model's architecture and interpretability methods, showing moderate to deep engagement rather than superficial mentions.

ImpactModerate impact

The discussions suggest that the methodology could influence future research, especially in cancer data analysis, indicating a moderate perceived impact.

Abstract in brief

The paper discusses a new deep learning strategy called CustOmics for integrating multiple types of omics data (like genetic, protein, and other biological data) to better understand diseases and build predictive models.
It introduces a two-phase approach where the model first trains independently on each data source and then learns how these sources interact, leading to more efficient use of all data types and more accurate predictions, especially for cancer classification and survival prediction.
Additionally, the method emphasizes interpretability by adapting to Shapley additive explanations, allowing researchers to understand how different data sources contribute to the predictions, with performance demonstrated across various cancer datasets.]

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CustOmics: Deep Learning Strategy for Multi-Omics Data Integration

CustOmics is a deep learning approach for integrating various omics data types to enhance disease understanding and prediction accuracy. The model first trains on individual data sources, then learns their interactions…

Social RTCL TV · Jun 18, 2023 21 views

Valen Guerreros

@GuerrerosValenn · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Apr 5, 2023 · 15 shares · 6 followers View post →

Lantiso

@LittNFTs · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Apr 4, 2023 · 15 shares · 57 followers View post →

Sadad Redwan

@SadadRedwan · X

A versatile deep-learning based strategy for multi-omics integration #Learning via https://t.co/6qPcNWrkFh https://t.co/LLsR67EMZl

Apr 3, 2023 · 498 followers View post →

Benters Mall

@BentersM · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Apr 1, 2023 · 15 shares · 856 followers View post →

nellister charles

@NellisterC · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 30, 2023 · 15 shares · 281 followers View post →

Stalwart

@the_unswerving · X

A versatile deep-learning based strategy for multi-omics integration #Learning via https://t.co/yNOfVDx5DP https://t.co/xo2bErz3Mc

Mar 25, 2023 · 578 followers View post →

S&M Telecommunications

@sm_telecomm · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 22, 2023 · 15 shares · 440 followers View post →

Antigoos

@antigoos_art · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 21, 2023 · 15 shares · 188 followers View post →

antisense.

@razoralign · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43qgMT https://t.co/Ow5yV7G0pN

Mar 13, 2023 · 2 likes · 15,931 followers View post →

Dmitry Svetlichnyy

@dmitry_svetlich · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 8, 2023 · 15 shares · 286 followers View post →

Kamal (卡馬爾) (@kamalmdm.bsky.social)

@KamalMdM · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 8, 2023 · 15 shares · 415 followers View post →

Hyungyong Kim

@yong27 · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 8, 2023 · 15 shares · 645 followers View post →

Saubashya Sur, PhD

@SaubashyaSur · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 8, 2023 · 15 shares · 768 followers View post →

In Absentia

@tiwarko37 · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 8, 2023 · 15 shares · 101 followers View post →

Toyota_Group_Komaba

@KomaToug · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 7, 2023 · 15 shares · 669 followers View post →

Seyoon Lee

@Seyoon_L · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 7, 2023 · 15 shares · 213 followers View post →

Xaira Rivera

@xaairg · X

RT @razoralign: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl…

Mar 7, 2023 · 15 shares · 382 followers View post →

antisense.

@razoralign · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/IkIk43pIXl https://t.co/tyFAfl5h1x

Mar 7, 2023 · 46 likes · 15 shares · 15,931 followers View post →

Oncology & Machine Learning

@MlOncology · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/0o5UWaCQh1

Mar 6, 2023 · 213 followers View post →

Omkar

@OmkarChandra · X

RT @Deep__AI: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/j1CA5Nd7c5 by Hakim Benkirane et…

Sep 19, 2022 · 2 shares · 200 followers View post →

arXiv Daily

@Arxiv_Daily · X

RT @Deep__AI: CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/j1CA5Nd7c5 by Hakim Benkirane et…

Sep 19, 2022 · 2 shares · 48,930 followers View post →

DeepAI

@DeepAI · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration https://t.co/j1CA5Nd7c5 by Hakim Benkirane et al. #DeepLearning #Autoencoder

Sep 18, 2022 · 8 likes · 2 shares · 53,996 followers View post →

Arxiv Bot

@BotArxiv · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration #QuantitativeBio #bio #biology #arxiv https://t.co/wL7xb7qTsj

Sep 14, 2022 · 40 followers View post →

Machine Learning in Chemistry

@ML_Chem · X

CustOmics: A versatile deep-learning based strategy for multi-omics integration. (arXiv:2209.05485v1 [https://t.co/RzFGwRLevZ]) #machinelearning https://t.co/CAAalOFuyj

Sep 14, 2022 · 5,264 followers View post →

CustOmics: A versatile deep-learning based strategy for multi-omics integration.

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CustOmics: Deep Learning Strategy for Multi-Omics Data Integration