AJP **Published Online:**9 Mar 2023 DOI: https://doi.org/10.1176/appi.ajp.20220312 URL…
Risk of Experiencing an Overdose Event for Patients Undergoing Treatment With Medication for Opioid Use Disorder.
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Mar 2023 – May 2023Where it's discussed
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X / Twitter11 posts
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YouTube2 videos
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Reddit2 posts
AI synopsis
What people are saying
Discussions focus on key aspects such as higher overdose risks associated with medication discontinuation and benzodiazepine use, with posts emphasizing the importance of medication adherence and informing treatment strategies; the tone and detailed references to hazard ratios indicate a serious and analytical engagement with the research's implications.
Most discussions agree that medication adherence and baseline benzodiazepine use are significant factors influencing overdose risk, reflected in statements like 'risk is elevated among those who fail to initiate or discontinue medication.'
The posts demonstrate high interest, with detailed mentions of clinical trial data, hazard ratios, and specific factors affecting overdose risk, indicating active engagement with the research.
Several discussions reference specific statistics, such as hazard ratios and trial sources, showing deep engagement with the methodological and clinical implications.
The findings are seen as impactful, highlighting issues like early overdose risks and medication management, though there’s less emphasis on policy change or broader societal implications.
Abstract in brief
- The study investigates the risk of overdose among patients undergoing medication for opioid use disorder (MOUD), finding that the overall risk over 24 weeks varies depending on medication adherence and patient characteristics.
- Patients who never started their assigned medication or discontinued early had higher overdose risks, especially if they used benzodiazepines at baseline.
- Using survival analysis, the researchers found no significant difference in overdose risk based solely on medication type (methadone, naltrexone, buprenorphine), but adherence and baseline substance use played crucial roles in overdose likelihood.]
Top posts
Most liked on X and BlueskyData from Laura Brandt @CityCollegeNY and colleagues drawn from three clinical trials indicate that patients undergoing medication treatment for #opioid use disorder have a non-negligible risk of overdose events in the first 24 weeks. https://t.co/yG4fVKgaED https://t.co/Q8VIS2rAKV
Risk of Experiencing an Overdose Event for Patients Undergoing Treatment With Medication for Opioid Use Disorder https://t.co/dnDdzUl24q
Among patients with opioid use disorder under treatment, the risk of overdose events is elevated among those who: 1) fail to initiate or discontinue medication, 2) report benzodiazepine use and 2) receive naltrexone instead of opiod maintenance. https://t.co/MwLzP6IGu4
AJP Deputy Editor Danny Pine highlights two articles from the May 2023 issue. https://t.co/yvjReUkvBV
RT @NIDAnews:
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Overdose Risk and Safety in Medication for Opioid Use Disorder Treatment
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses recent research on overdose risk in patients undergoing medication for opioid use disorder, highlighting the importance of medication adherence and…
Overdose Risk in Patients Undergoing Treatment for Opioid Use Disorder
This study investigates overdose risk among patients on medication for opioid use disorder, highlighting the importance of medication adherence and baseline substance use in overdose likelihood.
AJP Deputy Editor Danny Pine highlights two articles from the May 2023 issue. https://t.co/yvjReUkvBV
Risk of Experiencing an Overdose Event for Patients Undergoing Treatment With Medication for Opioid Use Disorder https://t.co/dnDdzUl24q
Among patients with OUD seeking treatment, the risk of overdose over the next 24 weeks is elevated among those who fail to initiate (HR=6.64; 2.12-19.54) or discontinue medication (4.04; 1.54-10.65) and those who use BZDs at baseline (3.36; 1.76-6.42) https://t.co/tUBcdEYBSm
Among patients with opioid use disorder under treatment, the risk of overdose events is elevated among those who: 1) fail to initiate or discontinue medication, 2) report benzodiazepine use and 2) receive naltrexone instead of opiod maintenance. https://t.co/MwLzP6IGu4
RT @NIDAnews:
RT @NIDAnews:
RT @NIDAnews:
RT @NIDAnews:
"Among patients with opioid use disorder seeking medication treatment, the risk of overdose events over the next 24 weeks is elevated among those who fail to initiate or discontinue medication and those who report benzodiazepine use at baseline." https://t.co/nAm2IvmP6w
Data from Laura Brandt @CityCollegeNY and colleagues drawn from three clinical trials indicate that patients undergoing medication treatment for #opioid use disorder have a non-negligible risk of overdose events in the first 24 weeks. https://t.co/yG4fVKgaED https://t.co/Q8VIS2rAKV
AJP Publicado en línea: 9 de marzo de 2023 DOI: https://doi.org/10.1176/appi.ajp.20220312 URL…
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