June 2023 PMID 36924284

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.

Rakshit S Tanna, James T Nguyen, Deena L Hadi, Matthew E Layton, John R White, Nadja B Cech, Nicholas H Oberlies, Allan E Rettie, Kenneth E Thummel, Mary F Paine

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Mentions

24
Peak: 4 in Apr 2023
across 3 sources since Mar 2023

Extended reach

15,042
potential audience

Total likes

23

Video views

146

Mentions per month

Mar 2023 – Sep 2024

Where it's discussed

  • X / Twitter19 posts
  • YouTube3 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reflect a balanced interest and recognition of the study's importance, with posts mentioning key findings like kratom's effect on liver enzymes and its role in managing opioid withdrawal, using words like 'potential drug interactions' and 'critical knowledge gaps.' The tone suggests a cautious but attentive attitude toward the implications of this research.

AgreementModerate agreement

Most discussions recognize the significance of the study, with some explicitly agreeing on its importance by highlighting its findings and implications.

InterestModerate interest

The posts demonstrate moderate interest, as they share the study's details without overly emotional language but show curiosity about the research developments.

EngagementModerate engagement

The engagement is moderate; some posts reference specific aspects like the chemical mechanisms and clinical relevance, indicating a thoughtful level of participation.

ImpactModerate impact

The overall perception is that this research is potentially impactful, especially given the emphasis on drug interactions and safety concerns associated with kratom.

Top posts

Most liked on X and Bluesky
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFVsip

Nov 17, 2023 · 4 likes · 2 shares · 321 followers View post →
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFW07X

May 6, 2024 · 2 likes · 1 share · 321 followers View post →
NaPDI
@NaPDICenter · X

Congrats to Rakshit Tanna from Paine lab selected as a recipient of the prestigious @ASCPT_ClinPharm 2023 Presidential Trainee Award for his abstract, “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom (Mitragyna speciosa).” https://t.co/P7rlkIwWPx

Dec 22, 2023 · 2 likes · 321 followers View post →
Kratom Science
@kratomscience · X

And there's a new human clinical study (Tanna et al 2023) showing kratom is a CYP3A inhibitor as previous in vitro studies have shown. This means "Co-consuming kratom with certain drugs extensively metabolized by CYP3A may precipitate serious interactions" https://t.co/gpOVHKKawE

Mar 17, 2023 · 1 like · 1 share · 4,322 followers View post →
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFVsip

Jul 21, 2023 · 1 like · 2 shares · 321 followers View post →
NaPDI
@NaPDICenter · X

Showcasing Rakshit Tanna from Paine lab who was selected as recipients of the prestigious @ASCPT_ClinPharm 2023 Presidential Trainee Award for his abstract, “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom (Mitragyna speciosa).” https://t.co/SLCU0hCgtA

Jun 14, 2024 · 1 like · 321 followers View post →

All mentions

NaPDI
@NaPDICenter · X

Kratom can interact with other meds! A new study shows it can increase the effects of some drugs metabolized by the liver, leading to dangerous side effects. https://t.co/WlcmzFwCrU #kratom #druginteractions #health #wellbeing #naturalproducts #NPDIs

Sep 16, 2024 · 321 followers View post →
NaPDI
@NaPDICenter · X

Showcasing Rakshit Tanna from Paine lab who was selected as recipients of the prestigious @ASCPT_ClinPharm 2023 Presidential Trainee Award for his abstract, “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom (Mitragyna speciosa).” https://t.co/SLCU0hCgtA

Jun 14, 2024 · 1 like · 321 followers View post →
ASCPT Journal Family
@ASCPTjournals · X

RT @NaPDICenter: Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on…

May 6, 2024 · 1 share · 592 followers View post →
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFW07X

May 6, 2024 · 2 likes · 1 share · 321 followers View post →
NaPDI
@NaPDICenter · X

Congrats to Rakshit Tanna from Paine lab selected as a recipient of the prestigious @ASCPT_ClinPharm 2023 Presidential Trainee Award for his abstract, “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom (Mitragyna speciosa).” https://t.co/P7rlkIwWPx

Dec 22, 2023 · 2 likes · 321 followers View post →
NaPDI
@NaPDICenter · X

We are excited to share our paper “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom” by Tanna, Nguyen, et al, accepted to #CPTJournal. See it here: https://t.co/WlcmzFwCrU #ASCPTJournalFamily @ASCPT_ClinPharm @ASCPTjournals

Dec 13, 2023 · 1 like · 321 followers View post →
ASCPT Alexandria
@ASCPT_ClinPharm · X

RT @NaPDICenter: Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on…

Nov 20, 2023 · 2 shares · 1,889 followers View post →
Susan Egbert, PharmD (she/her)
@lichenlady94 · X

RT @NaPDICenter: Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on…

Nov 17, 2023 · 2 shares · 1,500 followers View post →
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFVsip

Nov 17, 2023 · 4 likes · 2 shares · 321 followers View post →
Kratom Danger Awareness,Inc.
@Ch52471437Wendy · X

@SherryJOwings https://t.co/ZzcISRdyvO

Sep 21, 2023 · 382 followers View post →
ASCPT Journal Family
@ASCPTjournals · X

RT @NaPDICenter: Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on…

Jul 24, 2023 · 2 shares · 592 followers View post →
Susan Egbert, PharmD (she/her)
@lichenlady94 · X

RT @NaPDICenter: Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on…

Jul 21, 2023 · 2 shares · 1,500 followers View post →
NaPDI
@NaPDICenter · X

Study by @nadjacech @OberliesGroup et al reveals potential drug interactions with #kratom. Oral kratom formulations are on the rise for managing opioid withdrawal & pain. These data fill critical knowledge gaps about the safe use kratom. @ASCPT_ClinPharm https://t.co/bCfstFVsip

Jul 21, 2023 · 1 like · 2 shares · 321 followers View post →
ASCPT Journal Family
@ASCPTjournals · X

RT @NaPDICenter: Exciting new study out on the drug interaction potential of the psychotropic natural product kratom. Check out the article…

Apr 19, 2023 · 1 share · 592 followers View post →
NaPDI
@NaPDICenter · X

Exciting new study out on the drug interaction potential of the psychotropic natural product kratom. Check out the article by Tanna RS et al. in @ASCPTjournals Clinical Pharmacology & Therapeutics. #Kratom #DrugInteractions #ClinicalResearch https://t.co/WlcmzFwCrU

Apr 18, 2023 · 1 like · 1 share · 321 followers View post →
ASCPT Journal Family
@ASCPTjournals · X

RT @NaPDICenter: We are excited to share our paper “Clinical assessment of the drug interaction potential of the psychotropic natural produ…

Apr 13, 2023 · 1 share · 592 followers View post →
NaPDI
@NaPDICenter · X

We are excited to share our paper “Clinical assessment of the drug interaction potential of the psychotropic natural product kratom”, accepted to #CPTJournal. See it here: https://t.co/WlcmzFwCrU #ASCPTJournalFamily @ASCPTJournals

Apr 11, 2023 · 1 like · 1 share · 321 followers View post →
mooncrate.co
@mooncrate_co · X

RT @kratomscience: And there's a new human clinical study (Tanna et al 2023) showing kratom is a CYP3A inhibitor as previous in vitro studi…

Mar 25, 2023 · 1 share · 8 followers View post →
Kratom Science
@kratomscience · X

And there's a new human clinical study (Tanna et al 2023) showing kratom is a CYP3A inhibitor as previous in vitro studies have shown. This means "Co-consuming kratom with certain drugs extensively metabolized by CYP3A may precipitate serious interactions" https://t.co/gpOVHKKawE

Mar 17, 2023 · 1 like · 1 share · 4,322 followers View post →