Sci Data March 2023 PMID 36973297

An integrated single-cell transcriptomic dataset for non-small cell lung cancer.

Karolina Hanna Prazanowska, Su Bin Lim

Mentions

6
Peak: 3 in Mar 2023
across 3 sources since Mar 2023

Extended reach

2,375
potential audience

Total likes

2

Video views

33

Mentions per month

Mar 2023 – Jul 2023

Where it's discussed

  • X / Twitter3 posts
  • Reddit2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone reflects strong interest and recognition of the dataset's potential, with comments such as calling it a 'valuable resource' and discussing its ability to improve understanding of cell heterogeneity. Words like 'significant,' 'advancement,' and 'tool' highlight both the impact and engagement, while phrases like 'addressing issues' and 'validating approach' underscore technical depth and agreement.

AgreementModerate agreement

Most discussions acknowledge the significance of creating an extensive, integrated dataset for NSCLC research, showing general support.

InterestHigh interest

Participants demonstrate high curiosity and enthusiasm, often highlighting the potential for advancing understanding of tumor heterogeneity.

EngagementModerate engagement

Commenters reference specific aspects like the methodology and implications, indicating a meaningful level of deep engagement.

ImpactHigh impact

Many posts emphasize the importance of this dataset for future research and clinical applications, suggesting significant scientific impact.

Abstract in brief

  • The study combines seven different single-cell RNA sequencing datasets to create a large, integrated dataset of over 224,000 cells from human non-small cell lung cancer (NSCLC) tumors, addressing issues like small cohort sizes and limited cell type information.
  • The researchers used an anchor-based method to preprocess and merge the datasets, establishing two levels of cell type annotations and validating their approach with two separate datasets.
  • They demonstrated the usefulness of this integrated dataset by predicting cell types in validation data and performing trajectory analyses on specific groups of T cells and lung cancer cells, making it a valuable resource for NSCLC research.]

Top posts

Most liked on X and Bluesky
RNAseq_software
@RnaseqS · X

An integrated single-cell transcriptomic dataset for non-small cell lung cancer: As single-cell RNA sequencing (scRNA-seq) has emerged as a great tool for studying cellular heterogeneity within the past decade, the number of available scRNA-seq datasets… https://t.co/A5GVxZk8kw

Mar 29, 2023 · 2 likes · 1 share · 313 followers View post →
Transcriptomes
@transcriptomes · X

An integrated single-cell transcriptomic dataset for non-small cell lung cancer. https://t.co/s6DKK6mVqE

Mar 28, 2023 · 1,809 followers View post →

All mentions

Seyoon Lee
@Seyoon_L · X

RT @RnaseqS: An integrated single-cell transcriptomic dataset for non-small cell lung cancer: As single-cell RNA sequencing (scRNA-seq) has…

Mar 29, 2023 · 1 share · 216 followers View post →
RNAseq_software
@RnaseqS · X

An integrated single-cell transcriptomic dataset for non-small cell lung cancer: As single-cell RNA sequencing (scRNA-seq) has emerged as a great tool for studying cellular heterogeneity within the past decade, the number of available scRNA-seq datasets… https://t.co/A5GVxZk8kw

Mar 29, 2023 · 2 likes · 1 share · 313 followers View post →
Transcriptomes
@transcriptomes · X

An integrated single-cell transcriptomic dataset for non-small cell lung cancer. https://t.co/s6DKK6mVqE

Mar 28, 2023 · 1,809 followers View post →