Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications.

Abstract in brief

• Biomimetic natural biomaterials (BNBMs) are a promising alternative for tissue engineering and regenerative medicine because they mimic the extracellular matrix (ECM), providing beneficial biochemical and physical cues to support cell growth and tissue repair.
• Recent advancements include new methods for fabricating and customizing these materials to enhance their functionality, such as improving their mechanical properties, microstructure, and bioactivity to better replicate native tissue environments.
• The article discusses current challenges and future directions, emphasizing the potential of BNBMs in various applications, but also highlights the need for further research to overcome limitations and fully harness their regenerative capabilities.]