Physiological aspect of apoptosis-regulating microRNAs expressions during fasting.

Abstract in brief

• Fasting triggers complex cellular responses, including autophagy, stress pathways, and changes in hormone levels, with microRNAs (miRNAs) playing a key regulatory role in apoptosis.
• The study examined the expression levels of 19 miRNAs in saliva samples from healthy students who fasted for 17 hours versus those who ate, using real-time PCR, to understand how fasting influences apoptotic pathways.
• Results suggest that fasting modulates miRNAs to promote cell death, which could help prevent disease progression, such as cancer, by controlling abnormal cell growth, and this research may guide future studies on miRNAs’ roles in health and disease.