Nat Commun April 2023 PMID 37019924

Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product.

P Konstantin Richter, Paula Blázquez-Sánchez, Ziyue Zhao, Felipe Engelberger, Christian Wiebeler, Georg Künze, Ronny Frank, Dana Krinke, Emanuele Frezzotti, Yuliia Lihanova, Patricia Falkenstein, Jörg Matysik, Wolfgang Zimmermann, Norbert Sträter, Christian Sonnendecker

Download social card

Mentions

21
Peak: 4 in Apr 2023
across 4 sources since Apr 2023

Extended reach

8,100
potential audience

Total likes

8

Video views

209

Mentions per month

Apr 2023 – Jun 2024

Where it's discussed

  • News12 articles
  • X / Twitter4 posts
  • Reddit3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions emphasize the importance of enzyme improvements for plastic degradation, with mentions of the Leipzig research team's efforts and structural details, using words like 'efficiency' and 'congrats' to highlight positive recognition and excitement about the work’s potential environmental impact.

AgreementModerate agreement

Most discussions express positive reactions and support for the significance of the research, especially highlighting advancements made by the Leipzig team.

InterestHigh interest

Participants demonstrate strong interest, with mentions of additional articles, detailed descriptions of enzyme functions, and enthusiasm for the publication's implications.

EngagementModerate engagement

The discussion includes references to specific structural details, organism contributions, and recognition of the publication, indicating moderate to high level of engagement.

ImpactModerate impact

The conversations suggest that this research is seen as impactful, as relevant updates are shared across multiple platforms and people celebrate new publication findings.

Abstract in brief

  • The polyester hydrolase PHL7 has been identified as an effective enzyme for breaking down amorphous polyethylene terephthalate (PET) found in post-consumer plastics.
  • The study reveals the enzyme's structure in complex with terephthalic acid and examines how various mutations affect its ability to degrade PET and its thermal stability.
  • Key mutations, particularly L210T, enhance PHL7's activity, enabling it to degrade PET at a rate of 20 µm/h, while other mutations influence its thermal properties.

Top posts

Most liked on X and Bluesky
Enzycle - BBI
@enzycle_bbi · X

New #ENZYCLE publication in @NatureComms from @UniLeipzig! Read more about the "Structure and function of the metagenomic #plastic-degrading polyester hydrolase PHL7 bound to its product": https://t.co/QsFo1tjyRY Congrats!! @CBE_JU

Apr 7, 2023 · 3 likes · 115 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product https://t.co/UPxfJSj5Ax

Apr 6, 2023 · 3,702 followers View post →
Ordo Fraterna Fibonacci
@OrdoFibonacci · X

Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product | Nature Communications https://t.co/05Mr5k0sWa

Apr 12, 2023 · 2,569 followers View post →
BIOspektrum
@Spektrum_BIO · X

Ein Forschungsteam von der Universität Leipzig haben die Effizienz eines PET-abbauenden Enzyms gesteigert: https://t.co/orM41rB3xS Mehr Hintergrundinfos im BIOspektrum-Artikel von Christian Sonnendecker. https://t.co/YcVGMHknNK @UniLeipzig https://t.co/nFawMZqPrH

Apr 13, 2023 · 1,506 followers View post →

All mentions

BIOspektrum
@Spektrum_BIO · X

Ein Forschungsteam von der Universität Leipzig haben die Effizienz eines PET-abbauenden Enzyms gesteigert: https://t.co/orM41rB3xS Mehr Hintergrundinfos im BIOspektrum-Artikel von Christian Sonnendecker. https://t.co/YcVGMHknNK @UniLeipzig https://t.co/nFawMZqPrH

Apr 13, 2023 · 1,506 followers View post →
Ordo Fraterna Fibonacci
@OrdoFibonacci · X

Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product | Nature Communications https://t.co/05Mr5k0sWa

Apr 12, 2023 · 2,569 followers View post →
Enzycle - BBI
@enzycle_bbi · X

New #ENZYCLE publication in @NatureComms from @UniLeipzig! Read more about the "Structure and function of the metagenomic #plastic-degrading polyester hydrolase PHL7 bound to its product": https://t.co/QsFo1tjyRY Congrats!! @CBE_JU

Apr 7, 2023 · 3 likes · 115 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product https://t.co/UPxfJSj5Ax

Apr 6, 2023 · 3,702 followers View post →