March 2023 PMID 37051467

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos.

Kelli D Fenelon, Fan Gao, Priyanshi Borad, Shiva Abbasi, Lior Pachter, Theodora Koromila

Mentions

22
Peak: 6 in Mar 2023
across 2 sources since Dec 2022

Extended reach

162,949
potential audience

Total likes

51

Video views

516

Mentions per month

Dec 2022 – May 2024

Where it's discussed

  • X / Twitter15 posts
  • YouTube7 videos

AI synopsis

What people are saying

The discussions exhibit excitement about the publication's insights into how specific transcription factors influence embryo head formation, with phrases like 'officially out' and hashtags emphasizing the importance of the research. The tone is enthusiastic and focused on scientific curiosity, reflecting high interest and engagement while recognizing the research's potential impact.

AgreementModerate agreement

Most discussions express strong support and enthusiasm for the research findings.

InterestHigh interest

Posts show high curiosity about embryonic head development and epigenetics.

EngagementModerate engagement

Commenters actively share the article, ask questions, and reference specific details.

ImpactModerate impact

The discussions highlight the significance of understanding gene regulation in early development, suggesting moderate to high impact.

Abstract in brief

  • The study explores how two transcription factors, Opa and Oc, interact during early embryo development, particularly in shaping head cell fates, with Opa being important after Zelda for activating zygotic genes.
  • Using advanced microscopy and RNA sequencing, the researchers found that Opa and Oc are expressed simultaneously in the head region during the blastula stage, with Opa influencing a specific set of genes.
  • During later development stages, Oc binds to and activates head-specific genes independently, potentially competing with Opa for gene regulation, indicating that they have distinct yet overlapping roles in embryo head formation.]

Top posts

Most liked on X and Bluesky
Theodora Koromila
@t_koromila · X

Are you interested in embryonic head development? Our lab's 1st paper is officially out @FrontCellDevBio What are the Odd(s of) Paired Ocelliless dynamics? Check it out! https://t.co/aZSIA4xRNK Led by postdoc Kelli Fenelon! @UTABiologyDept @UTAScience

Mar 28, 2023 · 16 likes · 3 shares · 295 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos: During development, embryonic patterning systems direct a set of initially uncommitted… https://t.co/7ul82Bkzv2 #celldevbio

Mar 27, 2023 · 5 likes · 2 shares · 3,798 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos A Research article from the Koromila lab @t_koromila @UTABiologyDept @UTAScience ➡️https://t.co/AOac7G1Qd1 #epigenetics #Drosophila #embryo https://t.co/99Gk5lheyz

Apr 25, 2023 · 3 likes · 1 share · 3,798 followers View post →
Thomas Brody
@interactivefly · X

Fenelon, K. D., Gao, F., Borad, P., Abbasi, S., Pachter, L. and Koromila, T. (2023). Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos. Front Cell Dev Biol 11: 1126507 https://t.co/WRrRiMt9YR

Jun 21, 2023 · 3 likes · 2 shares · 2,024 followers View post →
bxv_dev
@bxv_dev · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos https://t.co/v3rRjrJMJg

Dec 16, 2022 · 1 like · 3,132 followers View post →
bioRxiv
@biorxivpreprint · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos https://t.co/xNWXf0zISA #bioRxiv

Dec 16, 2022 · 136,940 followers View post →

All mentions

Drosophila Genomics Resource Center
@DrosDGRC · X

RT @interactivefly: Fenelon, K. D., Gao, F., Borad, P., Abbasi, S., Pachter, L. and Koromila, T. (2023). Cell-specific occupancy dynamics…

Jun 23, 2023 · 2 shares · 2,043 followers View post →
Drosophilosopher
@HammedBadmos · X

RT @interactivefly: Fenelon, K. D., Gao, F., Borad, P., Abbasi, S., Pachter, L. and Koromila, T. (2023). Cell-specific occupancy dynamics…

Jun 21, 2023 · 2 shares · 1,366 followers View post →
Thomas Brody
@interactivefly · X

Fenelon, K. D., Gao, F., Borad, P., Abbasi, S., Pachter, L. and Koromila, T. (2023). Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos. Front Cell Dev Biol 11: 1126507 https://t.co/WRrRiMt9YR

Jun 21, 2023 · 3 likes · 2 shares · 2,024 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos A Research article from the Koromila lab @t_koromila @UTABiologyDept @UTAScience ➡️https://t.co/AOac7G1Qd1 #epigenetics #Drosophila #embryo https://t.co/99Gk5lheyz

Apr 25, 2023 · 3 likes · 1 share · 3,798 followers View post →
Nano IJ
@nanomicroscopy · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos https://t.co/3jbANTwQJV https://t.co/2LQEE4zf3X

Apr 13, 2023 · 594 followers View post →
regulonPapers
@regulon_papers · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos https://t.co/EngO5L23e9

Apr 13, 2023 · 37 followers View post →
Super Res Microscopy
@SRMicro_papers · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos by Kelli D Fenelon https://t.co/rT9fIYsn7i

Apr 13, 2023 · 3,124 followers View post →
Asela Wijeratne
@asela_1 · X

RT @t_koromila: Are you interested in embryonic head development? Our lab's 1st paper is officially out @FrontCellDevBio What are the Odd(…

Mar 28, 2023 · 3 shares · 512 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos Read #OpenAccess ➡️https://t.co/dcmW6iLJB2 #EmbryonicHeadDevelopment #epigenetics #Drosophila #embryo #CellDevBio https://t.co/PQr6hy83jo

Mar 28, 2023 · 3,798 followers View post →
Helen Yu
@Hypat1aYu · X

RT @t_koromila: Are you interested in embryonic head development? Our lab's 1st paper is officially out @FrontCellDevBio What are the Odd(…

Mar 28, 2023 · 3 shares · 639 followers View post →
Theodora Koromila
@t_koromila · X

Are you interested in embryonic head development? Our lab's 1st paper is officially out @FrontCellDevBio What are the Odd(s of) Paired Ocelliless dynamics? Check it out! https://t.co/aZSIA4xRNK Led by postdoc Kelli Fenelon! @UTABiologyDept @UTAScience

Mar 28, 2023 · 16 likes · 3 shares · 295 followers View post →
Theodora Koromila
@t_koromila · X

RT @FrontCellDevBio: New Research: Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate ear…

Mar 28, 2023 · 2 shares · 295 followers View post →
Frontiers - Cell Biology
@FrontCellDevBio · X

New Research: Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliless/OTX regulate early head development in embryos: During development, embryonic patterning systems direct a set of initially uncommitted… https://t.co/7ul82Bkzv2 #celldevbio

Mar 27, 2023 · 5 likes · 2 shares · 3,798 followers View post →
bxv_dev
@bxv_dev · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos https://t.co/v3rRjrJMJg

Dec 16, 2022 · 1 like · 3,132 followers View post →
bioRxiv
@biorxivpreprint · X

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos https://t.co/xNWXf0zISA #bioRxiv

Dec 16, 2022 · 136,940 followers View post →