Le chercheur Zheng-Yi Chen et son équipe de la Harvard Medical School ont mis au point une thérapie génique permettant la régénération des cellules ciliées. Un espoir pour tous ceux souffrant de surdité neurosensorielle https://t.co/YcAZ3vGPYi
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice.
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Apr 2023 – Feb 2024Where it's discussed
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X / Twitter41 posts
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News32 articles
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Reddit8 posts
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YouTube2 videos
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What people are saying
Several posts emphasize the groundbreaking nature of the research, using words like 'potential,' 'hope,' and 'game changer,' which reflect high interest and perceived importance. The tone varies from enthusiastic support to scientific acknowledgment, indicating that the audience recognizes the study's potential impact and engages deeply with both its methods and implications.
Most discussions express strong support and optimism for the research, highlighting its potential to revolutionize hearing loss treatment.
The discussions demonstrate high curiosity, with many comments emphasizing new scientific breakthroughs and potential cures.
Posts frequently reference specific scientific aspects, such as molecular cocktails and cellular pathways, showing deep engagement with the research details.
Many discussions underscore the significant implications for people suffering from hearing loss, suggesting the work could lead to transformative therapies.
Abstract in brief
- The study explores a new method to regenerate cochlear hair cell-like cells in adult mice using drug-like molecules that activate specific cellular pathways, potentially offering a solution for irreversible hearing loss.
- Researchers used single-cell RNA sequencing to show that activating MYCNICD, along with pathways such as Wnt and cAMP, can rejuvenate supporting cells and promote hair cell-like regeneration, even in mature, non-transgenic mice.
- A cocktail of small molecules and small interfering RNAs was developed to replace genetic modifications, successfully reprogramming mature supporting cells into hair cell-like cells both in vitro and in living mice, paving the way for potential hearing restoration therapies.]
Top posts
Most liked on X and BlueskyScientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1gzUs0PTS2 https://t.co/QrDuTTmiwx
Yay! Congrats to the Chen lab for getting this collaborative work published! https://t.co/eDMHBw0oQa
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice https://t.co/f5PhuTNLp5 @PNASNews https://t.co/NDOvqvage6
https://t.co/qBP2jc4CP6
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice | Proceedings of the National Academy of Sciences https://t.co/qBP2jc4CP6
All mentions
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Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice Yi-Zhou Quan et al. https://t.co/WhmQaGX2qE PNAS April 17, 2023 120 (17) e2215253120
RT @agingdoc1: Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice https://t.co/f5Ph…
RT @agingdoc1: Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice https://t.co/f5Ph…
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice https://t.co/f5PhuTNLp5 @PNASNews https://t.co/NDOvqvage6
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice | Proceedings of the National Academy of Sciences https://t.co/XVw6OjpwJJ
@elonmusk Agreed. Also, money for hearing aids = great. Better hearing aids = amazing. Money for a CURE for hearing loss (and tinnitus) = what is really needed. https://t.co/2s1tCPBn73 https://t.co/l9U8wHls5N
Potential for reversal of hearing loss. https://t.co/appZtO12bO
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice - https://t.co/dG54yQ8So4
Que linda que es la ciencia https://t.co/3Vr6Xrjjjm
Princeton University researchers may have found a way to repair hearing loss by regrowing the sensory cells in the inner ear
RT @EricKLein_: Le chercheur Zheng-Yi Chen et son équipe de la Harvard Medical School ont mis au point une thérapie génique permettant la r…
RT @EricKLein_: Le chercheur Zheng-Yi Chen et son équipe de la Harvard Medical School ont mis au point une thérapie génique permettant la r…
RT @EricKLein_: Le chercheur Zheng-Yi Chen et son équipe de la Harvard Medical School ont mis au point une thérapie génique permettant la r…
Le chercheur Zheng-Yi Chen et son équipe de la Harvard Medical School ont mis au point une thérapie génique permettant la régénération des cellules ciliées. Un espoir pour tous ceux souffrant de surdité neurosensorielle https://t.co/YcAZ3vGPYi
RT @gecko39: Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice 17APR2023 https://…
RT @gecko39: Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice | Proceedings of the…
https://t.co/qBP2jc4CP6
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice | Proceedings of the National Academy of Sciences https://t.co/qBP2jc4CP6
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice 17APR2023 https://t.co/qBP2jc4CP6 Proceedings of the National Academy of Sciences
Bilim insanları iç kulaktaki işitmeyi mümkün kılan tüy hücrelerini başarılı bir şekilde yenileyebileceğini söyledikleri moleküllerden oluşan yeni bir ilaç kokteyli geliştirdiklerini ve bunun işitme kaybı için çığır açabilecek bir tedavi olduğunu söylüyor. https://t.co/xsokNbv5P3 https://t.co/bKJh64NkHM
https://t.co/LHljQa1PlC
#Harvard being Harvard.. 1st #longevity, now they may have discovered a drug cocktail of molecules that can successfully #regenerate the (hair) #cells in the inner ear that enable hearing. Also 9/9 of these #scientists are Asian or Eastern European
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice: Strategies to overcome irreversible cochlear hair cell (HC) damage and loss in mammals are of vital importance to hearing recovery in patients with… https://t.co/ieIsPP0DJZ
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice | PNAS (April 17, 2023) https://t.co/imtZkohXBD
The researchers successfully regenerated cochlear hair cell-like cells in adult mice using a drug-like cocktail of molecules. https://t.co/U7DVaCibaJ
#Hope for those suffering #HearingLoss this findings will eventually find their way to humans. Thank you @harvardmed https://t.co/eeK69iiJag
Drug-Like Cocktail Used by Researchers to Regenerate Hair Cells for Hearing Loss in Preclinical Study https://t.co/shW9O91Tho Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice https://t.co/CU7RwNpodZ https://t.co/l2cUnyxCzf
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice | Proceedings of the National Academy of Sciences https://t.co/Dg8mpvIOGl
RT @IndArtur: Yay! Congrats to the Chen lab for getting this collaborative work published! https://t.co/eDMHBw0oQa
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
RT @medical_xpress: Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1…
Scientists use drug-like cocktail to regenerate #haircells in preclinical study @masseyeandear @PNASNews https://t.co/1gzUs0PTS2 https://t.co/QrDuTTmiwx
RT @IndArtur: Yay! Congrats to the Chen lab for getting this collaborative work published! https://t.co/eDMHBw0oQa
RT @IndArtur: Yay! Congrats to the Chen lab for getting this collaborative work published! https://t.co/eDMHBw0oQa
Yay! Congrats to the Chen lab for getting this collaborative work published! https://t.co/eDMHBw0oQa