PubHawk
May 2023 PMID 37075755

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery.

Sajedah M Hindi, Michael J Petrany, Elena Greenfeld, Leah C Focke, Alyssa A W Cramer, Michael A Whitt, Ramzi J Khairallah, Christopher W Ward, Jeffrey S Chamberlain, Benjamin Podbilewicz, Vikram Prasad, Douglas P Millay

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Mentions

68
Peak: 16 in Apr 2023
across 5 sources since Mar 2023

Extended reach

989,816
potential audience

Total likes

131

Video views

44

Mentions per month

Mar 2023 – May 2025

Where it's discussed

  • X / Twitter58 posts
  • News3 articles
  • Blogs3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Numerous discussions highlight the innovative aspects of the study, with phrases like 'bold new therapy delivery method' and 'initial promise as treatment for Duchenne muscular dystrophy' indicating a clear excitement among the audience. The use of enthusiastic language and supportive references, such as praising the researchers, contributes to a strong, positive sentiment surrounding the publication, showcasing the substantial potential of the findings in advancing therapeutic techniques.

AgreementStrong agreement

The majority of posts express strong support for the findings of the publication.

InterestHigh interest

Users show a high level of curiosity, generating discussions around the implications of the research.

EngagementHigh engagement

Many participants delve deep into the methods and potential applications of the study, reflecting a thorough understanding and consideration of the content.

ImpactHigh impact

There is a common belief that this research could significantly influence treatment methods, particularly for conditions like Duchenne muscular dystrophy.

Abstract in brief

  • Enveloped viruses use viral proteins to fuse with host cell membranes, similar to how skeletal muscle cells fuse to form myofibers.
  • Researchers investigated whether two muscle-specific fusogens, Myomaker and Myomerger, could replace viral fusogens in fusing viruses to cells.
  • The study found that modifying viruses with these fusogens enables targeted delivery of a therapeutic protein to skeletal muscle, showcasing a new method for treating conditions like Duchenne muscular dystrophy.
Read the full abstract

Top posts

Most liked on X and Bluesky
Cell
@CellCellPress · X

Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/ip8UkEpQdt

Apr 19, 2023 · 30 likes · 7 shares · 262,948 followers View post →
Joe Gordon
@josephwgordon · X

#myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/xpzGZMfLYR

Mar 25, 2023 · 20 likes · 5 shares · 2,107 followers View post →
Cell Press
@CellPressNews · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more from @CincyChildrens @doug_millay & colleagues in @CellCellPress #ASGCT2024 https://t.co/bwnm7wE0nH

May 11, 2024 · 19 likes · 8 shares · 160,929 followers View post →
AnnemiekeAartsma-Rus
@oligogirl · X

#apaperaday Actually 2 papers, as I read the @biorxivpreprint paper by Hindi et al and then discovered the paper is now also out in @CellCellPress in a slightly different form. Dois: doi: 10.1101/2023.03.17.533157 and 10.1016/j.cell.2023.03.033 https://t.co/FaXsUB4IZH

Jul 5, 2023 · 10 likes · 2 shares · 3,129 followers View post →
Cell
@CellCellPress · X

In the latest issue! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/Qf8v98ySRe

May 11, 2023 · 9 likes · 5 shares · 262,948 followers View post →
Olivier Schwartz Lab
@Virus_Immunity · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/HHyy5vrqlO

Apr 19, 2023 · 8 likes · 1 share · 3,556 followers View post →

All mentions

Ali Nik-Akhtar
@nikakhtar_ali · X

https://t.co/tL2R3SnB4o

Apr 1, 2025 · 1 like · 136 followers View post →
Ali Nik-Akhtar
@nikakhtar_ali · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery

Apr 1, 2025 · 1 like · 138 followers View post →
Russell Rogers, Ph.D.
@rrogerslab · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 12, 2024 · 8 shares · 170 followers View post →
Anny Velasquez Cruz
@AnnyVC19 · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 12, 2024 · 8 shares · 184 followers View post →
Shams Salah Mahdi
@ShamsPath · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 12, 2024 · 8 shares · 1,433 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 12, 2024 · 8 shares · 572 followers View post →
medic
@E329541 · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 12, 2024 · 8 shares · 82 followers View post →
Adriel Hernando
@adriel_hah · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 11, 2024 · 8 shares · 187 followers View post →
Keiichi Ito
@itok10918 · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 11, 2024 · 8 shares · 1,244 followers View post →
Jaroslav Novotný
@novotnyjarosl · X

RT @CellPressNews: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more…

May 11, 2024 · 8 shares · 602 followers View post →
Cell Press
@CellPressNews · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - read more from @CincyChildrens @doug_millay & colleagues in @CellCellPress #ASGCT2024 https://t.co/bwnm7wE0nH

May 11, 2024 · 19 likes · 8 shares · 160,929 followers View post →
TAU Virology
@tauvirulogy · X

רוצים לקרוא עוד? https://t.co/qx5CyfXTlN

Mar 10, 2024 · 6 likes · 548 followers View post →
Biology Technion
@BiologyTechnion · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/OhHk5CKzfN https://t.co/v7mVgBJ9Wj

Feb 5, 2024 · 2 likes · 386 followers View post →
NIAMS
@NIH_NIAMS · X

“Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery.” Read the study: https://t.co/5pDK2YE1yg

Aug 8, 2023 · 1 like · 13,780 followers View post →
Phage Papers
@Phage_Papers · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/ufOlw29Kxu

Aug 5, 2023 · 647 followers View post →
AnonRere
@AnonRere · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/cp7TWSvEsr

Aug 4, 2023 · 2,223 followers View post →
Virginia Arechavala
@VArechavala · X

RT @oligogirl: #apaperaday Actually 2 papers, as I read the @biorxivpreprint paper by Hindi et al and then discovered the paper is now also…

Jul 6, 2023 · 2 shares · 2,253 followers View post →
Marie Pichaske
@mpichaske · X

RT @oligogirl: #apaperaday Actually 2 papers, as I read the @biorxivpreprint paper by Hindi et al and then discovered the paper is now also…

Jul 5, 2023 · 2 shares · 481 followers View post →
AnnemiekeAartsma-Rus
@oligogirl · X

#apaperaday Actually 2 papers, as I read the @biorxivpreprint paper by Hindi et al and then discovered the paper is now also out in @CellCellPress in a slightly different form. Dois: doi: 10.1101/2023.03.17.533157 and 10.1016/j.cell.2023.03.033 https://t.co/FaXsUB4IZH

Jul 5, 2023 · 10 likes · 2 shares · 3,129 followers View post →
Raviranjan Kumar
@Raviran57397338 · X

RT @BottinoAltamiro: Bold new therapy delivery method shows initial promise as treatment for Duchenne muscular dystrophy https://t.co/c6mw…

Jun 21, 2023 · 1 share · 10 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

Bold new therapy delivery method shows initial promise as treatment for Duchenne muscular dystrophy https://t.co/c6mwQ5ym5L https://t.co/PbT3zLWX1T https://t.co/k11iNcwRXI

Jun 13, 2023 · 1 share · 93 followers View post →
chuanwen shen
@ChuanwenShen · X

https://t.co/TgZCKWY5pC

Jun 2, 2023 · 2 followers View post →
Deshmukh_Lab
@LabDeshmukh · X

https://t.co/CmSrWv2Nvt Tour de force work from @doug_millay and colleagues at # CCHMC and Heart Institute. Congratulations @doug_millay

May 25, 2023 · 3 likes · 240 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/7Wsf1jzZAr https://t.co/6U5GGgTtEb

May 19, 2023 · 24,206 followers View post →
S.HIROMITSU
@S_HIROMI2 · X

膜融合で感染するレンチウイルスのエンベロープタンパク質をヒト筋細胞由来のFusogeneに置換した結果,MYMKを発現する筋細胞に特異的に感染するベクターができた話. 全身隈無く存在する筋細胞へのDDとして有用である事を,マウス筋ジストロフィーモデルを用いて示している. https://t.co/6fnu3AYSEK

May 12, 2023 · 44 followers View post →
Terry Hoover
@TerryHo70841353 · X

RT @CellCellPress: In the latest issue! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene…

May 12, 2023 · 5 shares · 400 followers View post →
Neil Gerardo-MRX Chairman- ID#32140089
@NeilGerardo · X

RT @CellCellPress: In the latest issue! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene…

May 11, 2023 · 5 shares · 791 followers View post →
CP☁️
@callmepoi_p · X

RT @CellCellPress: In the latest issue! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene…

May 11, 2023 · 5 shares · 141 followers View post →
Cell
@CellCellPress · X

In the latest issue! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/Qf8v98ySRe

May 11, 2023 · 9 likes · 5 shares · 262,948 followers View post →
PubMed Trending
@PubTrend · X

Trending on PubMed: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery. https://t.co/SKhMtyyZb6

May 7, 2023 · 1 like · 5,155 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/BjrJNbOQxd https://t.co/EnOgQwRVkt

May 4, 2023 · 24,206 followers View post →
JWeltner
@WeltnerJ · X

RT @ControllingLMNT: Whoa. "Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery".…

May 2, 2023 · 3 shares · 61 followers View post →
Moshe Dessau
@StructureRocks · X

RT @ControllingLMNT: Whoa. "Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery".…

Apr 28, 2023 · 3 shares · 123 followers View post →
Pavel
@Pavel74099739 · X

RT @ControllingLMNT: Whoa. "Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery".…

Apr 27, 2023 · 3 shares · 20 followers View post →
Edward Grow, PhD
@ControllingLMNT · X

Whoa. "Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery". https://t.co/GQC7GeT3l5 https://t.co/C0xED2FwXI

Apr 27, 2023 · 7 likes · 3 shares · 1,684 followers View post →
Karthikeyan Ponnienselvan
@thisiskpselvan · X

RT @CellCellPress: Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene deliver…

Apr 21, 2023 · 7 shares · 30 followers View post →
Phenomics
@Phenomics_J · X

RT @agingdoc1: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery

Apr 21, 2023 · 2 shares · 1,528 followers View post →
DHprotein
@DHprotein · X

RT @CellCellPress: Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene deliver…

Apr 20, 2023 · 7 shares · 15 followers View post →
Joao Pereira
@jdpereira · X

RT @agingdoc1: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery

Apr 20, 2023 · 2 shares · 8,200 followers View post →
Agingdoc
@agingdoc1 · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery

Apr 20, 2023 · 4 likes · 2 shares · 41,343 followers View post →
Phage Papers
@Phage_Papers · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/bhorGpoYLc

Apr 20, 2023 · 647 followers View post →
Phenomics
@Phenomics_J · X

RT @CellCellPress: Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene deliver…

Apr 19, 2023 · 7 shares · 1,528 followers View post →
womens-rights
@medscicomms1920 · X

RT @CellCellPress: Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene deliver…

Apr 19, 2023 · 7 shares · 310 followers View post →
Cell
@CellCellPress · X

Now online! Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/ip8UkEpQdt

Apr 19, 2023 · 30 likes · 7 shares · 262,948 followers View post →
AnonRere
@AnonRere · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/fntEuvmI78

Apr 19, 2023 · 2,223 followers View post →
LivingwithFSHD
@LivingwithFSHD · X

RT @josephwgordon: Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - ScienceDi…

Apr 19, 2023 · 1 share · 551 followers View post →
Olivier Schwartz Lab
@Virus_Immunity · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/HHyy5vrqlO

Apr 19, 2023 · 8 likes · 1 share · 3,556 followers View post →
Joe Gordon
@josephwgordon · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery - ScienceDirect https://t.co/8JlMo12aNX

Apr 18, 2023 · 2 likes · 1 share · 2,107 followers View post →
Phage Papers
@Phage_Papers · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/TFoMERkl1X

Mar 30, 2023 · 647 followers View post →
#myotwítter
@MYOTWlTTER · X

RT @josephwgordon: #myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery…

Mar 25, 2023 · 5 shares · 1,262 followers View post →
LivingwithFSHD
@LivingwithFSHD · X

RT @josephwgordon: #myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery…

Mar 25, 2023 · 5 shares · 551 followers View post →
cristofer calvo
@cristofercalvo3 · X

RT @josephwgordon: #myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery…

Mar 25, 2023 · 5 shares · 2 followers View post →
Chris Ward
@Chris_W_Ward · X

RT @josephwgordon: #myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery…

Mar 25, 2023 · 5 shares · 531 followers View post →
Matthew S. Alexander
@Matt_Muscle_Guy · X

RT @josephwgordon: #myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery…

Mar 25, 2023 · 5 shares · 5,446 followers View post →
Joe Gordon
@josephwgordon · X

#myotwitter Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/xpzGZMfLYR

Mar 25, 2023 · 20 likes · 5 shares · 2,107 followers View post →
Biorxiv Reddit
@BiorxivReddit · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/1Qkid1eBx2

Mar 19, 2023 · 39 followers View post →
bioRxiv Cell Biology
@biorxiv_cellbio · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/AUorq1lReC #biorxiv_cellbio

Mar 19, 2023 · 7,645 followers View post →
bioRxiv
@biorxivpreprint · X

Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery https://t.co/dtu6pX7q15 #bioRxiv

Mar 19, 2023 · 1 like · 136,937 followers View post →