BMC Psychiatry April 2023 PMID 37076806

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study.

Zibo Gao, Biao Li, Xinru Guo, Wei Bai, Changgui Kou

Mentions

10
Peak: 7 in Apr 2023
across 3 sources since Apr 2023

Extended reach

100,196
potential audience

Total likes

12

Video views

950

Mentions per month

Apr 2023 – Jul 2023

Where it's discussed

  • X / Twitter7 posts
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions express strong interest and agreement by referencing the study’s findings on immune cell levels and their relevance, e.g., phrases like 'suggesting the need for monitoring' and 'implicating immune response' convey both curiosity and recognition of clinical importance. The tone and word choice reflect a mix of scientific curiosity and cautious optimism about the potential impact on understanding and managing schizophrenia.

AgreementModerate agreement

Most discussions recognize the study's findings linking schizophrenia with elevated white blood cell counts, showing general consensus on its significance.

InterestHigh interest

Posts demonstrate high curiosity about the potential clinical implications, such as monitoring inflammatory responses in patients.

EngagementModerate engagement

Some comments delve into methodological aspects and consider how this research could influence future studies or treatment approaches.

ImpactModerate impact

Observers see this research as potentially impacting clinical practices and understanding of schizophrenia's biological underpinnings, though it remains an emerging area.

Abstract in brief

  • This study used bidirectional Mendelian randomization analyses to explore whether there is a causal relationship between schizophrenia and white blood cell (WBC) counts, including specific types like lymphocytes, neutrophils, basophils, eosinophils, and monocytes, finding evidence that genetically predicted schizophrenia increases WBC levels.
  • The results suggest a positive association where a genetic predisposition to schizophrenia is linked to higher counts of certain WBCs, especially basophils, eosinophils, monocytes, lymphocytes, and neutrophils, indicating that schizophrenia may influence immune cell levels rather than the other way around.
  • The reverse analysis did not find evidence that WBC counts causally affect the risk of developing schizophrenia, implying that elevated WBC levels are likely a consequence rather than a cause of schizophrenia.]

Top posts

Most liked on X and Bluesky
BMC
@BioMedCentral · X

A study published in #BMCPsychiatry finds that schizophrenia is associated with elevated levels of white blood cells count, suggesting the need for monitoring these traits and the management of low-grade inflammatory responses. https://t.co/HjC6iv5FLj

Apr 26, 2023 · 3 likes · 1 share · 75,347 followers View post →
MR_lit
@Mendelian_lit · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/eBR6M6VAyX

Apr 20, 2023 · 1 like · 1,835 followers View post →
Psychiatric Genomics Bot
@PsychGenPapers · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/JYpjrB4RcR

Apr 20, 2023 · 1 like · 1 share · 180 followers View post →
BMC Series
@BMC_series · X

RT @BioMedCentral: A study published in #BMCPsychiatry finds that schizophrenia is associated with elevated levels of white blood cells cou…

Apr 27, 2023 · 1 share · 21,318 followers View post →
CopperKettle
@Artyom_Yekat · X

RT @PsychGenPapers: The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization s…

Apr 20, 2023 · 1 share · 387 followers View post →
robo_gwas
@robo_gwas · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/xusBbsKWo9

Apr 20, 2023 · 170 followers View post →

All mentions

BMC Series
@BMC_series · X

RT @BioMedCentral: A study published in #BMCPsychiatry finds that schizophrenia is associated with elevated levels of white blood cells cou…

Apr 27, 2023 · 1 share · 21,318 followers View post →
BMC
@BioMedCentral · X

A study published in #BMCPsychiatry finds that schizophrenia is associated with elevated levels of white blood cells count, suggesting the need for monitoring these traits and the management of low-grade inflammatory responses. https://t.co/HjC6iv5FLj

Apr 26, 2023 · 3 likes · 1 share · 75,347 followers View post →
robo_gwas
@robo_gwas · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/xusBbsKWo9

Apr 20, 2023 · 170 followers View post →
MR_lit
@Mendelian_lit · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/eBR6M6VAyX

Apr 20, 2023 · 1 like · 1,835 followers View post →
CopperKettle
@Artyom_Yekat · X

RT @PsychGenPapers: The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization s…

Apr 20, 2023 · 1 share · 387 followers View post →
Psychiatric Genomics Bot
@PsychGenPapers · X

The association between schizophrenia and white blood cells count: a bidirectional two-sample Mendelian randomization study https://t.co/JYpjrB4RcR

Apr 20, 2023 · 1 like · 1 share · 180 followers View post →
Dr. Charles Noplis
@DrCharlesNoplis · X

The association between schizophrenia and white blood cells count ... - BMC Psychiatry https://t.co/wn3Asm0zvN

Apr 19, 2023 · 2 followers View post →