Infect Dis Poverty April 2023 PMID 37095536

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis.

Jing-Xian Yin, Yannick Luther Agbana, Zhi-Shan Sun, Si-Wei Fei, Han-Qing Zhao, Xiao-Nong Zhou, Jun-Hu Chen, Kokouvi Kassegne

Download social card

Mentions

64
Peak: 27 in Apr 2023
across 2 sources since Apr 2023

Extended reach

423,153
potential audience

Total likes

89

Video views

122

Mentions per month

Apr 2023 – May 2025

Where it's discussed

  • X / Twitter63 posts
  • YouTube1 videos

AI synopsis

What people are saying

Numerous posts highlight the findings of the publication, citing specific roles of interleukin-6 in predicting long COVID—certain users emphasize phrases like 'high levels could serve as a predictor' and 'this study showed elevated IL-6 correlates with long COVID'. These choices of words and the tone reflect a sense of urgency and potential for actionable insights, suggesting a significant interest among users in further research and treatment implications.

AgreementModerate agreement

Many discussions express support for the claims made in the article regarding the association of interleukin-6 with long COVID.

InterestHigh interest

Participants actively engage and show a strong curiosity about the implications of the findings on IL-6 and long COVID.

EngagementModerate engagement

While some users provide basic acknowledgments, others delve into specific details like IL-6's role in various biological processes, indicating moderate engagement.

ImpactHigh impact

The discussions reflect a belief that the findings can greatly influence research directions and clinical practices concerning long COVID.

Abstract in brief

  • The study investigates the potential link between interleukin-6 (IL-6) levels and long COVID-19, amidst previous evidence suggesting IL-6's role in COVID-19.
  • A systematic review and meta-analysis included 22 studies, which revealed that long COVID-19 patients had significantly higher IL-6 levels compared to healthy controls and those with non-postacute sequelae of SARS-CoV-2.
  • The findings highlight the consistent elevation of IL-6 in long COVID-19, suggesting that IL-6 may be a critical biomarker for understanding and managing this condition.

Top posts

Most liked on X and Bluesky
Danielle Beckman
@DaniBeckman · X

@TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials for treat it. I don't know what else to say to convince these PCPs. https://t.co/kJQd82CxGM https://t.co/Re5NTT5S6m

Apr 7, 2024 · 26 likes · 7 shares · 38,780 followers View post →
Francisco Mera Cordero
@mera_cordero · X

https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhrIhGr3

Apr 25, 2023 · 15 likes · 5 shares · 6,185 followers View post →
Billy Hanlon
@bhanlon15 · X

'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 24, 2023 · 13 likes · 4 shares · 13,660 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis | Infectious Diseases of Poverty https://t.co/Bxk5qxOmGY

Apr 24, 2023 · 5 likes · 2 shares · 34,726 followers View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis. “serum levels of IL-6 were found to be significantly elevated in patients after COVID-19 infection, whether in the acute or long COVID-19 phase. “ https://t.co/yLt00DHO3m

Aug 2, 2023 · 4 likes · 1 share · 8,893 followers View post →
BJP
@brandondataguy · X

Growing body of evidence of cytokines in the early stages of Long Covid: 'This study showed that increased IL-6 correlates with long COVID-19... suggests IL-6 as a basic determinant to predict long COVID-19 or ... the "early stage" of long COVID-19.' https://t.co/OIaCbIDgBz

Apr 25, 2023 · 4 likes · 1 share · 729 followers View post →

All mentions

thetranscendedman
@atranscendedman · X

https://t.co/zE8adnnl4m https://t.co/lOZ01qG4qo https://t.co/vTTsoOE9m5 etc

May 19, 2025 · 1 like · 7,200 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysisIncreased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis - Infectious Diseases of Poverty https://t.co/tFvbZqSY8O

May 9, 2025 · 1 like · 9,042 followers View post →
Psychiatry Excellence
@psycheureka · X

RT @mryoung151: @psycheureka These particular cytokines are implicated in covid and löngcövid. https://t.co/yLt00DHO3m https://t.co/oHaX…

May 9, 2025 · 1 share · 10,022 followers View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

@psycheureka These particular cytokines are implicated in covid and löngcövid. https://t.co/yLt00DHO3m https://t.co/oHaXrqoEv2

May 9, 2025 · 1 like · 1 share · 8,893 followers View post →
Dr Judy VaccinePLUS - Novavax JN1 Feb 25
@JudyandHuahua · X

RT @Rob66733000: @quay_dr Increased IL-6 is associated with long COVID. IL-6 is a primary regulator of fibrinogen synthesis and drives the…

Dec 28, 2024 · 1 share · 2,569 followers View post →
Rob C
@Rob66733000 · X

@quay_dr Increased IL-6 is associated with long COVID. IL-6 is a primary regulator of fibrinogen synthesis and drives the development of fibrosis. Also regulates: the immune response, hematopoiesis, the acute phase response, and the central nervous system https://t.co/08W3zR1Tlp. https://t.co/jgZRpYnnY8

Dec 27, 2024 · 2 likes · 1 share · 1,067 followers View post →
Squirrely Dangie
@Angie_BoPeepers · X

There's at least 1 and it took me 1 second to google https://t.co/Q13wIFlj6k https://t.co/4UMhUWV2fg

Jul 13, 2024 · 2 likes · 1,936 followers View post →
Gerard Hough
@GerardHough · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis https://t.co/snrrS7M2t0

Jun 9, 2024 · 1,738 followers View post →
Daniel Brittain Dugger
@dbdugger · X

Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity. https://t.co/GwEkJYLKCA

Apr 18, 2024 · 1 like · 17,766 followers View post →
It's Not OK
@BetterEarth2024 · X

RT @dbdugger: There is actually a biological reason for many experiencing suicidal ideation, as well. As is observed in those who experienc…

Apr 18, 2024 · 1 share · 623 followers View post →
Daniel Brittain Dugger
@dbdugger · X

There is actually a biological reason for many experiencing suicidal ideation, as well. As is observed in those who experience suicidal ideation, those living with a chronic SARS-Cov-2 have elevated IL-6. https://t.co/GwEkJYLKCA

Apr 18, 2024 · 2 likes · 1 share · 17,766 followers View post →
Dee
@winthrop317 · X

RT @DaniBeckman: @pamelarbishop Excellent, thank you! I suggest you keep checking your IL-6 levels whenever possible. There are some studie…

Apr 9, 2024 · 1 share · 993 followers View post →
$444.5/$500 PLEASE RT
@blankdelight · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 222 followers View post →
robstonge
@robstonge11 · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 979 followers View post →
Danielle Beckman
@DaniBeckman · X

@pamelarbishop Excellent, thank you! I suggest you keep checking your IL-6 levels whenever possible. There are some studies (this is just one), suggesting that IL-6 can be a basic determinant to predict long COVID or at least inform on the “early stage” of long COVID-19. https://t.co/kJQd82CxGM

Apr 8, 2024 · 3 likes · 1 share · 38,780 followers View post →
lay wants u to check the pinned
@layabadeer · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 9,891 followers View post →
Autisdick
@hiimchiralkthx · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 1,465 followers View post →
mack_longcovid
@mack_Kartikeya · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 547 followers View post →
Dee
@winthrop317 · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 8, 2024 · 7 shares · 993 followers View post →
ApocaLiz
@Lizzardo77 · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 7, 2024 · 7 shares · 3,040 followers View post →
Caroline
@TheShoeLady33 · X

RT @DaniBeckman: @TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials f…

Apr 7, 2024 · 7 shares · 1,719 followers View post →
Danielle Beckman
@DaniBeckman · X

@TheShoeLady33 IL-6 cannot only indicate the "early stage" of long-term COVID-19 but is also involved in clinical trials for treat it. I don't know what else to say to convince these PCPs. https://t.co/kJQd82CxGM https://t.co/Re5NTT5S6m

Apr 7, 2024 · 26 likes · 7 shares · 38,780 followers View post →
Rob C
@Rob66733000 · X

@inkblue01 Also increased interleukin-6 which is associated with long COVID-19. https://t.co/XvnlMW3tYZ Along with lower cortisol levels and elevated levels of a protein called galectin-1. https://t.co/hICSBywWhT. Many biomarkers to be used together possibly as a predictor of long covid ?

Feb 23, 2024 · 1,067 followers View post →
trainerrueben
@trainerrueben · X

This study showed that increased IL-6 correlates with long COVID-19. https://t.co/X0tHYJ8lcN

Jan 28, 2024 · 952 followers View post →
Froglet
@froglet80 · X

@syd_nrho @PhillyPhile215 Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis https://t.co/kaZuvNG8Mt

Jan 22, 2024 · 4,931 followers View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

@Debblues @fitterhappierAJ https://t.co/yLt00DHO3m

Jan 20, 2024 · 1 like · 8,893 followers View post →
Tom Andrews
@0bj3ctivity · X

"Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis" https://t.co/Fdq1ELPw1b 5/x

Jan 4, 2024 · 5,478 followers View post →
Jackalope
@Jackalo08043309 · X

@janiesaysyay @NieceOfFester @CharlesRixey @NestCommander @EduEngineer "Long Covid" is a largely a consequence of poor nutrition and stagnant living. Replacing a healthy terrain with synthetic treatments generally exacerbates negative outcomes. https://t.co/Ga7XMC6Zgl.

Nov 23, 2023 · 73 followers View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis. “serum levels of IL-6 were found to be significantly elevated in patients after COVID-19 infection, whether in the acute or long COVID-19 phase. “ https://t.co/yLt00DHO3m

Aug 2, 2023 · 4 likes · 1 share · 8,893 followers View post →
Rob C
@Rob66733000 · X

@Catinmyfamily IL6 is elevated. "Increased IL-6 correlates with long COVID-19 ... IL-6 as a basic determinant to predict long COVID-19" and it's proposed that "IL-6 in the host immune pathway contributes to the development of long-term symptoms of COVID-19" https://t.co/Ls1n4xv3id

Jul 17, 2023 · 1,067 followers View post →
Missouri Beef Trick
@SibylVans · X

https://t.co/VnI2bINz8Z

Jun 22, 2023 · 40 followers View post →
Yannick Luther Agbana
@YAgbana · X

We have recently published a paper in Infectious Disease of Poverty (IF=10.485). The evidence-based study that we conducted demonstrated that high Interleukin-6 level is associated with long COVID. Follow the link to read more. https://t.co/OAYGi5sTRx #health #covid #sarscov2 https://t.co/x9Rx0iPrct

May 22, 2023 · 116 followers View post →
Yann Academy
@Yann_Academy · X

abnormally elevated level of IL-6 in COVID-19 patients can predict long COVID-19 occurrence. Follow the link to read more. https://t.co/znDVqHWxjP

May 22, 2023 · 2 likes · 8 followers View post →
Lavandula
@EigentlichAktiv · X

#Longcovid "This study showed that increased IL-6 correlates with long COVID-19. Such an informative revelation suggests IL-6 as a basic determinant to predict long COVID-19 or at least inform on the “early stage” of long COVID-19." https://t.co/rzcudqshzt

May 15, 2023 · 173 followers View post →
Infectious Diseases of Poverty
@Idpbmc2012 · X

Increased levels of interleukin-6 (IL-6) have been linked to long COVID-19, according to a systematic review and meta-analysis of 22 studies. #LongCovid #IL6 #COVID19 https://t.co/PWcrS0nP1e

May 4, 2023 · 1 like · 447 followers View post →
Infectious Diseases of Poverty
@Idpbmc2012 · X

RT @BioMedCentral: A Scoping Review published in Infectious Diseases of Poverty finds the increased interleukin-6 is associated with long C…

May 3, 2023 · 1 share · 447 followers View post →
Infirmière 3.0
@infirmiere_3_0 · X

RT @dlang57500: L'augmentation de l'#interleukine6 ​​est associée à un #covidlong: une revue systématique et une méta-analyse #longcovid h…

Apr 29, 2023 · 2 shares · 1,136 followers View post →
BMC
@BioMedCentral · X

A Scoping Review published in Infectious Diseases of Poverty finds the increased interleukin-6 is associated with long COVID and high levels of this immune mediator could serve as a predictor of long COVID. https://t.co/nFeJGaJsde

Apr 28, 2023 · 1 share · 75,347 followers View post →
Dominique Lang
@dlang57500 · X

RT @dlang57500: L'augmentation de l'#interleukine6 ​​est associée à un #covidlong: une revue systématique et une méta-analyse #longcovid h…

Apr 27, 2023 · 2 shares · 7,012 followers View post →
Dar Long
@darlingdarlon · X

Les hope this generates more research into IL6 blockers as potential treatment. https://t.co/2aKGGE9HpL

Apr 26, 2023 · 1 like · 715 followers View post →
@COVID_Evidence
@COVID_Evidence · X

RT @COVID_Evidence: PubMed: Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis: CONCLUSIONS:…

Apr 26, 2023 · 2 shares · 2,115 followers View post →
Dominique Lang
@dlang57500 · X

L'augmentation de l'#interleukine6 ​​est associée à un #covidlong: une revue systématique et une méta-analyse #longcovid https://t.co/QgsBgK9vMA

Apr 26, 2023 · 2 likes · 2 shares · 7,012 followers View post →
AIREyVIDA aquí no contamos casos, los prevenimos
@AIREyVIDA2021 · X

RT @mera_cordero: https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhr…

Apr 25, 2023 · 5 shares · 1,732 followers View post →
Dr. León Islas Weinstein
@LeonIslasW · X

RT @mera_cordero: https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhr…

Apr 25, 2023 · 5 shares · 172 followers View post →
Long Covid & ME/CFS Weekly
@LongCovidWeekly · X

RT @biotechbuzznews: Growing body of evidence of cytokines in the early stages of Long Covid: 'This study showed that increased IL-6 correl…

Apr 25, 2023 · 1 share · 1,628 followers View post →
BJP
@brandondataguy · X

Growing body of evidence of cytokines in the early stages of Long Covid: 'This study showed that increased IL-6 correlates with long COVID-19... suggests IL-6 as a basic determinant to predict long COVID-19 or ... the "early stage" of long COVID-19.' https://t.co/OIaCbIDgBz

Apr 25, 2023 · 4 likes · 1 share · 729 followers View post →
雅博
@zdF4QJ19JwebFEO · X

RT @Dakota_150: 'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 25, 2023 · 4 shares · 666 followers View post →
Long COVID Research
@StudyLongCOVID · X

Increased interleukin-6 is associated with long COVID-19: a ... - Infectious Diseases of Poverty - BioMed Central https://t.co/GTCeXGCmdA #longCOVID #news

Apr 25, 2023 · 93 followers View post →
Laurence
@laurenceide69 · X

RT @COVID_Evidence: PubMed: Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis: CONCLUSIONS:…

Apr 25, 2023 · 2 shares · 2,765 followers View post →
abigail stern- artist
@abigailstern1 · X

RT @Dakota_150: 'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 25, 2023 · 4 shares · 19,573 followers View post →
Sáfárné Hatrágyi Henrietta
@HatragyiSafarne · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis.

Apr 25, 2023 · 493 followers View post →
Leyre_G.
@leyre_gp · X

RT @mera_cordero: https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhr…

Apr 25, 2023 · 5 shares · 1,053 followers View post →
claudia rodriguez
@civonne · X

RT @mera_cordero: https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhr…

Apr 25, 2023 · 5 shares · 101 followers View post →
@COVID_Evidence
@COVID_Evidence · X

PubMed: Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis: CONCLUSIONS: This study showed that increased IL-6 correlates with long COVID-19. Such an informative revelation… https://t.co/MlwTHrGFEo #covid19 #SARSCOV2 #coronavirus

Apr 25, 2023 · 2 likes · 2 shares · 2,115 followers View post →
Francisco Mera Cordero
@mera_cordero · X

https://t.co/wWsnSPKque El aumento de IL-6 está asociado con #covidpersistente #biomarcadores #EMF/SFC https://t.co/LAbhrIhGr3

Apr 25, 2023 · 15 likes · 5 shares · 6,185 followers View post →
LongCovidPapers
@LongCovidPapers · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis https://t.co/5BE9yXP9Mt #LongCovid #pwLC

Apr 25, 2023 · 2,143 followers View post →
Awakened Guardian
@Tian_A1 · X

Increased interleukin-6 is associated with #Long COVID-19: a [ https://t.co/OmsIpNfPA6 ] #Coronavirus disease 2019 (#Covid19) can involve persistence, sequelae, Analysis of data was undertaken by using Cochran's Q test and the Higgins

Apr 25, 2023 · 2,020 followers View post →
Awakened Guardian
@Tian_A1 · X

Increased interleukin-6 is associated with #Long COVID-19: a [ https://t.co/OmsIpNfPA6 ] #Coronavirus disease 2019 (#Covid19) can involve persistence, sequelae, and other clinical complications that last weeks to months to evolve into long

Apr 24, 2023 · 2,020 followers View post →
charlos
@loscharlos · X

RT @Dakota_150: 'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 24, 2023 · 4 shares · 26,486 followers View post →
Suski
@SuskiFi · X

RT @Dakota_150: 'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 24, 2023 · 4 shares · 174 followers View post →
Ana Calber
@amcalber · X

RT @BagaiDr: Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis | Infectious Diseases of Pover…

Apr 24, 2023 · 2 shares · 2,271 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis | Infectious Diseases of Poverty https://t.co/Bxk5qxOmGY

Apr 24, 2023 · 5 likes · 2 shares · 34,726 followers View post →
Billy Hanlon
@bhanlon15 · X

'Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis' https://t.co/X8gHM17sUO

Apr 24, 2023 · 13 likes · 4 shares · 13,660 followers View post →