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Aging (Albany NY) April 2023 PMID 37100462

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform.

Andrea Olsen, Zachary Harpaz, Christopher Ren, Anastasia Shneyderman, Alexander Veviorskiy, Maria Dralkina, Simon Konnov, Olga Shcheglova, Frank W Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Ivan V Ozerov, Alex Aliper, Mikhail Korzinkin, Alex Zhavoronkov

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Mentions

35
Peak: 22 in May 2023
across 4 sources since Apr 2023

Extended reach

525,191
potential audience

Total likes

40

Video views

219

Mentions per month

Apr 2023 – Aug 2023

Where it's discussed

  • X / Twitter28 posts
  • News4 articles
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

The digital discussions emphasize the potential impact of the study by describing it as 'very interesting' and discussing it in formats like webinars and news reports, demonstrating both enthusiasm and recognition of its innovative use of AI. The tone varies from supportive praise to curiosity about the method, reflecting a generally positive perception and acknowledgment of its significance in biomedical research.

AgreementModerate agreement

Most discussions support the significance of the research, highlighting its potential for advancing therapies for aging and brain cancer.

InterestHigh interest

Posts show high interest, with mentions of AI techniques and dual-purpose therapeutic targets, indicating curiosity about innovative approaches.

EngagementModerate engagement

Some users explore the study's methods and implications, although the overall engagement remains moderate rather than deep.

ImpactHigh impact

The conversations suggest the research could have a meaningful influence on future therapies, emphasizing its importance.

Abstract in brief

  • This study uses AI, specifically PandaOmics, to find genes that could be targeted to treat both glioblastoma multiforme (GBM), a deadly brain cancer, and aging, since they share some underlying biological drivers.
  • Researchers developed three strategies combining gene correlation, survival data, and aging-related gene information to identify promising therapeutic targets that influence both conditions.
  • They highlight three potential targets—cyclic nucleotide gated channel subunit alpha 3, glutamate dehydrogenase 1, and sirtuin 1—that might be effective in treating both aging and GBM, offering a new approach for dual-purpose therapies.]
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Top posts

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Medical Xpress
@medical_xpress · X

High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https://t.co/oJfEOjDGD7

Apr 27, 2023 · 12 likes · 5 shares · 172,891 followers View post →
Medical Xpress
@medical_xpress · X

High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https://t.co/oJfEOjDGD7

May 1, 2023 · 8 likes · 4 shares · 172,891 followers View post →
Aging Science News
@AgingBiology · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform https://t.co/sXk9g53PWe

May 28, 2023 · 7 likes · 2 shares · 31,454 followers View post →
Agingdoc
@agingdoc1 · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform Andrea Olsen, @biogerontology et al. https://t.co/9SPGQz2JB1 @AgingJrnl | @youth_longevity @InSilicoMeds https://t.co/i54MC129vW

Apr 27, 2023 · 6 likes · 2 shares · 43,746 followers View post →
Andreea Nitescu RD MSc
@AndreeaNRD · X

Very interesting paper by @biogerontology & colleagues:

Aug 26, 2023 · 3 likes · 1,304 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform https://t.co/Sur9Q1dwZj

Apr 27, 2023 · 2 likes · 1 share · 18,675 followers View post →

All mentions

Andreea Nitescu RD MSc
@AndreeaNRD · X

Very interesting paper by @biogerontology & colleagues:

Aug 26, 2023 · 3 likes · 1,304 followers View post →
Aging-US
@AgingJrnl · X

Go #BehindTheStudy w/ @InSilicoMeds's Geoffrey Leung & Doris Leung as they discuss: “Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics – an AI-enabled biological target discovery platform.” https://t.co/QWXx5wPs79

Aug 15, 2023 · 4,400 followers View post →
Lifeboat Foundation
@LifeboatHQ · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics — an AI-enabled biological target discovery platform https://t.co/3B4YHUgQcg

Jun 2, 2023 · 1 like · 30,663 followers View post →
Phenomics
@Phenomics_J · X

RT @AgingBiology: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - a…

May 29, 2023 · 2 shares · 1,521 followers View post →
BitFuturist
@BitFuturist · X

RT @AgingBiology: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - a…

May 28, 2023 · 2 shares · 1,153 followers View post →
Aging Science News
@AgingBiology · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform https://t.co/sXk9g53PWe

May 28, 2023 · 7 likes · 2 shares · 31,454 followers View post →
SpaceAix Teacher
@DnaCowgirl · X

RT @cathcoste: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-…

May 19, 2023 · 1 share · 591 followers View post →
SpaceAix Teacher
@DnaCowgirl · X

RT @agingdoc1: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-…

May 19, 2023 · 2 shares · 591 followers View post →
SpaceAix
@cathcoste · X

RT @agingdoc1: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-…

May 19, 2023 · 2 shares · 5,405 followers View post →
SpaceAix
@cathcoste · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform | Aging https://t.co/Mznzt18rAS

May 18, 2023 · 1 share · 5,405 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

May 11, 2023 · 4 shares · 1,787 followers View post →
La veille techno
@laVeilleTechno · X

RT @NeveuxBertrand:

May 3, 2023 · 1 share · 11,160 followers View post →
Bertrand Neveux
@NeveuxBertrand · X

May 3, 2023 · 1 like · 1 share · 233 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

May 2, 2023 · 5 shares · 1,787 followers View post →
Nutriop Longevity
@nutriop · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform | Aging https://t.co/JjYroGbGH1

May 2, 2023 · 81 followers View post →
Michael Reitz
@MrReitz · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

May 1, 2023 · 4 shares · 130 followers View post →
Manu Gupta
@guptam108 · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

May 1, 2023 · 4 shares · 1,076 followers View post →
Medical Xpress
@medical_xpress · X

High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https://t.co/oJfEOjDGD7

May 1, 2023 · 8 likes · 4 shares · 172,891 followers View post →
Medical Xpress
@physorg_health · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

May 1, 2023 · 4 shares · 7,022 followers View post →
Dr. Siham Sabri, Ph.D.
@SabriSiham · X

RT @weldeiry: Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-e…

Apr 28, 2023 · 1 share · 1,211 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform https://t.co/Sur9Q1dwZj

Apr 27, 2023 · 2 likes · 1 share · 18,675 followers View post →
Tomasz Mrowicki
@tomrowicki · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

Apr 27, 2023 · 5 shares · 1,038 followers View post →
Agingdoc
@agingdoc1 · X

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform Andrea Olsen, @biogerontology et al. https://t.co/9SPGQz2JB1 @AgingJrnl | @youth_longevity @InSilicoMeds https://t.co/i54MC129vW

Apr 27, 2023 · 6 likes · 2 shares · 43,746 followers View post →
Manu Gupta
@guptam108 · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

Apr 27, 2023 · 5 shares · 1,076 followers View post →
andromeda
@astroid_belt · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

Apr 27, 2023 · 5 shares · 103 followers View post →
Medical Xpress
@physorg_health · X

RT @medical_xpress: High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https:…

Apr 27, 2023 · 5 shares · 7,022 followers View post →
Medical Xpress
@medical_xpress · X

High school student researchers find new brain tumor drug targets using AI @InSilicoMeds https://t.co/ZgAjIo3jeo https://t.co/oJfEOjDGD7

Apr 27, 2023 · 12 likes · 5 shares · 172,891 followers View post →
Y. Nagata
@nyooshi · X

英米中の高校生が香港のインシリコ・メディスン社のインターンシップで、脳腫瘍を治療する創薬の標的候補となる３つの遺伝子を、AIを使って見つけた論文（https://t.co/4pgvBDv6FA）＞日本でもどんどんやればいい。 https://t.co/TuP76Tvg6o

Apr 27, 2023 · 371 followers View post →
Using PandaOmics to identify dual-purpose therapeutic targets to ...
Blogs

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging ... doi.org/10.18632/aging.204678. Currently rated 5.0 by 2 people.

May 3, 2023 View →
Multi-Angled Approach of Identifying Dual-Purpose Therapeutic ...
News

Aging. doi.org/10.18632/aging.204678. Be the first to rate this article. Posted in: Drug Discovery & Pharmaceuticals | Molecular & Structural ...

May 3, 2023 View →
Targets Implicated in Aging and Glioblastoma Multiforme Using ...
News

... aging. Image Credit: Insilico Medicine. PandaOmics is used to determine ... doi.org/10.18632/aging.204678. Source: https://insilico.com ...

May 3, 2023 View →
Dual-purpose therapeutic targets for aging and glioblastoma ...
News

Journal. Aging-US. DOI. 10.18632/aging.204678. Method of Research. Computational simulation/modeling. Subject of Research. Not applicable ...

May 2, 2023 View →
High school student researchers find new brain tumor drug targets ...
News

Andrea Olsen and Zachary Harpaz initially presented findings around glioblastoma and aging at the Aging ... DOI: 10.18632/aging.204678. Key ...

May 1, 2023 View →