Signal Transduct Target Ther April 2023 PMID 37117161

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus.

Ye Sang, Zhen Zhang, Fan Liu, Haitao Lu, Changxiao Yu, Huisheng Sun, Jinrong Long, Yiming Cao, Jierui Mai, Yiqi Miao, Xin Wang, Jiaxin Fang, Youchun Wang, Weijin Huang, Jing Yang

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Mentions

Peak: 4 in Apr 2023

across 4 sources since Apr 2023

Extended reach

3,950

potential audience

Total likes

Video views

126

Mentions per month

Apr 2023 – Jul 2023

Where it's discussed

X / Twitter6 posts
News2 articles
Blogs2 articles
YouTube1 videos

AI synopsis

What people are saying

Participants are highly engaged with discussions emphasizing the vaccine's ability to induce strong immune responses, with phrases like 'induces immune response' and 'protects against vaccinia virus' showing clear understanding and focus. Repeated mentions of 'monkeypox' and 'vaccinia' reflect interest in vaccine efficacy, and the inclusion of terms like 'promising' and 'potential' indicates recognition of its high impact on future disease control efforts.

AgreementStrong agreement

All discussions strongly reinforce the positive findings and potential of the vaccine, emphasizing its promising immune response and protective effects.

InterestHigh interest

The frequent mention of the vaccine research and related health issues indicates high curiosity and concern among participants.

EngagementHigh engagement

Many discussions reference specific aspects of the study, such as immune responses and vaccine efficacy, showing deep engagement.

ImpactHigh impact

The emphasis on vaccine development, protection against viruses, and implications for public health demonstrates high perceived significance.

Abstract in brief

The study developed two novel quadrivalent mRNA vaccines, mRNAALNP and mRNABLNP, targeting monkeypox virus (MPXV) by using specific proteins associated with different virus forms.
When tested in mice, these vaccines triggered strong immune responses, including MPXV-specific antibodies, T-cell responses, and long-lasting immune cell memory, and successfully protected mice from vaccinia virus (VACV) challenge.
The findings suggest that mRNAALNP and mRNABLNP are promising, safe, and effective vaccine candidates for monkeypox and potentially other related viruses like smallpox, leveraging the successful mRNA platform used during COVID-19.]

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All mentions

Monkeypox Quadrivalent mRNA Vaccine Induces Immunity and Offers Protection

Medicine RTCL TV · Jul 26, 2023 126 views

Signal Transduction and Targeted Therapy (STTT)

@sigtrans_sttt · X

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus #Monkeypox virus #vaccinia https://t.co/lJ8gcok7qa

May 24, 2023 · 499 followers View post →

Prometheus

@PrometheusClstr · X

New article: Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus https://t.co/l7iwO25u3M

May 13, 2023 · 32 followers View post →

Long COVID Research

@StudyLongCOVID · X

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus: https://t.co/pe3VAXzsxh #longCOVID #research

Apr 30, 2023 · 93 followers View post →

ImmuneGCPapers

@ImmuneGC_Papers · X

GC | Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus https://t.co/9aFQFuxYCv

Apr 29, 2023 · 403 followers View post →

Phage Papers

@Phage_Papers · X

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus https://t.co/xj4ulJupsU

Apr 29, 2023 · 647 followers View post →

LongCovidPapers

@LongCovidPapers · X

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus #LongCovid #pwLC https://t.co/Sme0U3nilk

Apr 29, 2023 · 2,150 followers View post →