Nat Aging January 2023 PMID 37118510

Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain.

Matthew T Buckley, Eric D Sun, Benson M George, Ling Liu, Nicholas Schaum, Lucy Xu, Jaime M Reyes, Margaret A Goodell, Irving L Weissman, Tony Wyss-Coray, Thomas A Rando, Anne Brunet

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The discussions surrounding the publication emphasize its innovative approach to quantifying aging by analyzing how specific brain cells age and rejuvenate. Phrases like 'game changer' and descriptions of the techniques as 'cutting-edge' contribute to an enthusiastic tone, indicating users believe this research could significantly influence neuroscience and therapeutic strategies.

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Many posts indicate a supportive stance towards the publication's findings, highlighting excitement about the implications of aging clocks.

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The posts reflect a high degree of curiosity about aging research and its applications, suggesting that the topic resonates with others.

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The majority of posts are primarily supportive or informative rather than deeply analytical, indicating moderate engagement.

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Several users express belief in the substantial influence this research may have on future studies and health interventions.

Abstract in brief

Researchers created aging clocks using single-cell transcriptomics to measure aging and rejuvenation in specific brain cell types, particularly in the neurogenic regions.
They analyzed brain samples from 28 mice of different ages to develop models that predict both chronological and biological age, showing these models can apply to other mice, brain regions, and even different species.
The study found that interventions like heterochronic parabiosis and exercise can reverse transcriptomic aging in neurogenic regions, although they do so through different mechanisms.

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Antienvejecimiento: cerebro, nutrición y espíritu - Dra. Montoya y Dra. Ladino

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Referencias científicas Buckley MT, et al. Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain. Nat Aging. 2023 Jan;3(1):121-137. doi: 10.1038/s43587-022-00335-4. Epub 2022 Dec 19. PMID: 37118510; PMCID: PMC10154228. Wu Z, Qu J,

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Cell type-specific aging clocks to quantify aging and rejuvenation in regenerative regions of the brain.More time to hold #Bitcoin.

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In @NatureAging, @BrunetLab @Stanford developed cell-type-specific aging clocks to quantify #aging and rejuvenation in a neurogenic region of the mouse brain.

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science aging

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Cell type-specific aging clocks to quantify aging and rejuvenation in regenerative regions of the brain https://t.co/EMu0yBjr2U This @biorxivpreprint from the @BrunetLab @Stanford @Nick_Schaum @jaime_m_reyes @wysscoray @irvingweissman & colleagues,1st author Matthew Buckley

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Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain.

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Antienvejecimiento: cerebro, nutrición y espíritu - Dra. Montoya y Dra. Ladino

【VTuberが研究紹介してみた】残りの寿命知りたい？ #新人Vtuber #Vtuber #バーチャルYoutuber #shorts #解説

【VTuberが研究紹介してみた】残りの寿命知りたい？　#新人Vtuber #Vtuber #バーチャルYoutuber #shorts #解説