Front Microbiol April 2023 PMID 37125171

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study.

Mengchan Su, Yidan Tang, Weishuang Kong, Shuangyi Zhang, Tao Zhu

Download social card

Mentions

7
Peak: 4 in May 2023
across 3 sources since Apr 2023

Extended reach

34,297
potential audience

Total likes

7

Video views

12

Mentions per month

Apr 2023 – Dec 2024

Where it's discussed

  • X / Twitter5 posts
  • YouTube1 videos
  • Instagram1 posts

AI synopsis

What people are saying

Discussion content reflects mainly supportive reactions, with mentions of terms like 'causality' and 'gut microbiota,' emphasizing the study’s importance. Words like 'new research' and hashtags such as '#microbiome' indicate interest, while the tone remains somewhat neutral and exploratory, showing recognition of the study's potential impact without intense debate.

AgreementModerate agreement

Many posts acknowledge the significance of the research, with some referencing it as important evidence linking gut health to low back pain, indicating a general supportive stance.

InterestModerate interest

Posts show moderate curiosity, often highlighting the study's novel approach and potential implications without delving deeply into scientific details.

EngagementNeutral engagement

Few discussions go beyond basic acknowledgment; there are some mentions of the methodology like Mendelian randomization, but overall engagement remains moderate.

ImpactModerate impact

The posts suggest the study could influence future research directions and clinical considerations, though not perceived as revolutionary.

Abstract in brief

  • This study investigates the causal relationship between gut microbiota and low back pain (LBP) using a Mendelian randomization approach, analyzing data from various genome-wide association studies (GWAS).
  • The results identified 20 gut microbial taxa and 2 metabolites linked to LBP, with specific taxa indicating stronger risks for developing LBP even after corrections for multiple comparisons.
  • Analysis indicated no significant heterogeneity or pleiotropy affecting the results, and introducing body mass index (BMI) diminished the association between gut microbes and LBP, suggesting factors like BMI could influence or confound these relationships.

Top posts

Most liked on X and Bluesky
Sáfárné Hatrágyi Henrietta
@HatragyiSafarne · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study.

May 1, 2023 · 3 likes · 1 share · 494 followers View post →
Frontiers - Microbiology
@FrontMicrobiol · X

New Research: Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study https://t.co/GbYzwANbl9 #microbiology

Apr 23, 2023 · 2 likes · 1 share · 24,457 followers View post →
Microbiome Articles
@microbe_article · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample mendelian randomization... - Su M et al. - https://t.co/ibBd7cTtjT #microbiome

May 1, 2023 · 2 likes · 7,151 followers View post →
MR_lit
@Mendelian_lit · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study https://t.co/JhiFN6NoEN

May 2, 2023 · 1,835 followers View post →

All mentions

MR_lit
@Mendelian_lit · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study https://t.co/JhiFN6NoEN

May 2, 2023 · 1,835 followers View post →
YES
@ejoooj12 · X

RT @HatragyiSafarne: Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian rand…

May 1, 2023 · 1 share · 332 followers View post →
Sáfárné Hatrágyi Henrietta
@HatragyiSafarne · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study.

May 1, 2023 · 3 likes · 1 share · 494 followers View post →
Microbiome Articles
@microbe_article · X

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample mendelian randomization... - Su M et al. - https://t.co/ibBd7cTtjT #microbiome

May 1, 2023 · 2 likes · 7,151 followers View post →
Frontiers - Microbiology
@FrontMicrobiol · X

New Research: Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study https://t.co/GbYzwANbl9 #microbiology

Apr 23, 2023 · 2 likes · 1 share · 24,457 followers View post →
A capacidade de questionar “porquê?” é mais poderosa do que ...
Instagram

Não basta aceitar a primeira resposta; o verdadeiro conhecimento surge quando investigamos o que está na origem de cada sintoma. Cada “porquê” ...

Dec 9, 2024 View →