Nat Commun May 2023 PMID 37130861

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives.

Bei Huang, Steven W H Chau, Yaping Liu, Joey W Y Chan, Jing Wang, Suk Ling Ma, Jihui Zhang, Paul K S Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, Sunny Hei Wong, Vincent C T Mok, Ka Fai To, Hei Ming Lai

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Mentions

43
Peak: 17 in May 2023
across 6 sources since May 2023

Extended reach

69,931
potential audience

Total likes

22

Video views

155

Mentions per month

May 2023 – Aug 2025

Where it's discussed

  • X / Twitter17 posts
  • News14 articles
  • Facebook5 posts
  • Blogs3 articles
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  • Reddit2 posts

AI synopsis

What people are saying

The overall discussions show a strong interest in the potential of gut microbiome analysis for early diagnosis of Parkinson's-related conditions, with posts highlighting the importance of microbial markers and the disease's progression. The tone combines curiosity and optimism, indicating a recognition of the study's significance but also considering the need for further validation.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, highlighting the potential for gut microbiota as a diagnostic tool and emphasizing its relevance to Parkinson's disease and sleep disorders.

InterestHigh interest

The posts demonstrate high curiosity, focusing on novel findings about microbiome alterations and their implications for early disease detection, suggesting strong engagement with the topic.

EngagementModerate engagement

While some comments reference specific microbial markers and potential diagnostic applications, others stay at a general level, indicating moderate but meaningful engagement.

ImpactModerate impact

The discussions convey that the research could influence future diagnostic approaches and treatment strategies, though some posts remain optimistic rather than conclusive.

Abstract in brief

  • The microbiota-gut-brain axis may significantly influence Parkinson's disease (PD), prompting a study to analyze gut microbiota in early PD, REM sleep behavior disorder (RBD), first-degree relatives of RBD (RBD-FDR), and healthy controls.
  • Alterations in gut microbiota types were found in early PD and RBD, showing a decrease in beneficial butyrate-producing bacteria and an increase in pro-inflammatory Collinsella compared to controls.
  • The research identifies 12 microbial markers that could potentially differentiate RBD from healthy individuals, suggesting gut microbiota changes may occur before full-blown PD symptoms manifest, hinting at important diagnostic and treatment opportunities.

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Microbiome Articles
@microbe_article · X

Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relatives. - Huang B et al. - https://t.co/aqMG50h1Gz #microbiome

May 3, 2023 · 9 likes · 3 shares · 7,156 followers View post →
Agingdoc
@agingdoc1 · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/18z4lcMKz5 @NatureComms https://t.co/sWkBEENaHN

May 8, 2023 · 8 likes · 1 share · 41,778 followers View post →
New neuroscience papers in Nature Communications
@NeuroPaperBot · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/88R5aKnlhR

May 2, 2023 · 3 likes · 1,953 followers View post →
Rene Sugar
@renesugar · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/RUkVsvnWkG

May 9, 2023 · 1 like · 1 share · 3,969 followers View post →
Sleep Research
@SleepResearch_ · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives https://t.co/pbTgnmG345

May 3, 2023 · 7,257 followers View post →
Dr Marjorie Ghisoni PhD
@DrMGhisoni · X

RT @microbe_article: Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relative…

May 3, 2023 · 3 shares · 2,952 followers View post →

All mentions

Gut Microbiome and Parkinson's Disease Risk Analysis

Groundbreaking research reveals that gut bacteria play a crucial role in protecting our brain. Dietary changes like consuming almonds, spinach, and sweet potatoes can strengthen your gut and safeguard your nervous…

Dr. O · Aug 9, 2025 147 views
kike
@FUENTESMANZULLI · X

RT @renesugar: Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives htt…

May 9, 2023 · 1 share · 249 followers View post →
Rene Sugar
@renesugar · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/RUkVsvnWkG

May 9, 2023 · 1 like · 1 share · 3,969 followers View post →
Bayar Jaff
@JaffBayar · X

RT @agingdoc1: Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives htt…

May 8, 2023 · 1 share · 604 followers View post →
Agingdoc
@agingdoc1 · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/18z4lcMKz5 @NatureComms https://t.co/sWkBEENaHN

May 8, 2023 · 8 likes · 1 share · 41,778 followers View post →
Joanne Bei Huang
@hb_joanne · X

RT @ParkinsonJC: Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives.…

May 5, 2023 · 1 share · 5 followers View post →
Ingentium Parkinson's Disease
@Ingentium_PD · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. https://t.co/HaCwUoMM1y https://t.co/4nADYlcZ1F

May 3, 2023 · 512 followers View post →
Parkinson's Disease Articles
@ParkinsonJC · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives. https://t.co/4q168kd6FJ

May 3, 2023 · 1 share · 30 followers View post →
Phenomics
@Phenomics_J · X

RT @microbe_article: Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relative…

May 3, 2023 · 3 shares · 1,526 followers View post →
Dr Marjorie Ghisoni PhD
@DrMGhisoni · X

RT @microbe_article: Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relative…

May 3, 2023 · 3 shares · 2,952 followers View post →
HostMicrobiomePapers
@HostMicroPapers · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives https://t.co/nen4rscoXR https://t.co/hfN6Fsgv5b

May 3, 2023 · 190 followers View post →
Shiva Shankar S
@BioShankar · X

RT @microbe_article: Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relative…

May 3, 2023 · 3 shares · 162 followers View post →
Sleep Research
@SleepResearch_ · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives https://t.co/pbTgnmG345

May 3, 2023 · 7,257 followers View post →
micropapers
@micro_papers · X

Gut microbiome dysbiosis across early Parkinson's disease, REM sleep behavior disorder and their first-degree relatives https://t.co/ULNqWQaGaT

May 3, 2023 · 331 followers View post →
Microbiome Articles
@microbe_article · X

Gut microbiome dysbiosis across early parkinson's disease, rem sleep behavior disorder and their first-degree relatives. - Huang B et al. - https://t.co/aqMG50h1Gz #microbiome

May 3, 2023 · 9 likes · 3 shares · 7,156 followers View post →
Be The Light GB
@bethelightgb · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/lNJCo4EdSG

May 2, 2023 · 101 followers View post →
New neuroscience papers in Nature Communications
@NeuroPaperBot · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives https://t.co/88R5aKnlhR

May 2, 2023 · 3 likes · 1,953 followers View post →
Dataemia
@Dataemia · X

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives - https://t.co/cbQerBzxBj -

May 2, 2023 · 966 followers View post →