Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. https://t.co/BUHgQqVDM5
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease.
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May 2023 – Aug 2023Where it's discussed
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X / Twitter20 posts
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News2 articles
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YouTube1 videos
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What people are saying
The discussions show high enthusiasm, with phrases like 'excited about our work' and 'promising new therapy,' indicating strong support and focus on the research's potential impact. The tone emphasizes significance and innovation, especially regarding nanotechnology and autophagy, reflecting deep engagement with the study's approach and implications.
Most discussions express strong support and enthusiasm for the research findings and their potential implications.
The posts demonstrate high interest, highlighting the significance of the study in advancing NAFLD treatments and nanotechnology applications.
Comments reference specific aspects such as the method of restoring lysosomal acidity and the translation to therapy, indicating active engagement.
Participants believe the research could be transformative for NAFLD treatment and nanotechnology use in medicine.
Abstract in brief
- NAFLD is the most common liver disease and is caused by high free fatty acids that disrupt lysosomal acidification and autophagy.
- Researchers developed biodegradable acid-activating nanoparticles (acNPs) that specifically target and restore lysosomal acidity in liver cells, improving autophagy and mitochondrial function.
- In mouse models with NAFLD, treatment with acNPs reversed liver fat buildup and metabolic issues, suggesting these nanoparticles could be a promising new therapy for NAFLD.
Top posts
Most liked on X and BlueskyExcited about our work being published in @NatureComms - @OrianShirihai @JialiuZeng @xuehan #nanotechnology applications in #NAFLD treatment https://t.co/CN7HgGNmgC #liverdisease #autophagy @BU_Tweets https://t.co/pU1XRKR8li https://t.co/ofKRJDorIc
Check out Professor Mark Grinstaff's recently co-authored a paper in Nature Communications, "Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease." https://t.co/iyskuYUUgj
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @Grinstaff: Excited about our work being published in @NatureComms - @OrianShirihai @JialiuZeng @xuehan #nanotechnology applications in…
All mentions
Restoring Lysosomal Acidification Rescues Liver Cell Function in NAFLD
NAFLD causes liver dysfunction by disrupting lysosomal acidification and autophagy. Researchers developed acid-activating nanoparticles to restore lysosomal acidity, improving autophagy, metabolism, and reversing liver…
Check out Professor Mark Grinstaff's recently co-authored a paper in Nature Communications, "Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease." https://t.co/iyskuYUUgj
RT @Grinstaff: Excited about our work being published in @NatureComms - @OrianShirihai @JialiuZeng @xuehan #nanotechnology applications in…
RT @Grinstaff: Excited about our work being published in @NatureComms - @OrianShirihai @JialiuZeng @xuehan #nanotechnology applications in…
Excited about our work being published in @NatureComms - @OrianShirihai @JialiuZeng @xuehan #nanotechnology applications in #NAFLD treatment https://t.co/CN7HgGNmgC #liverdisease #autophagy @BU_Tweets https://t.co/pU1XRKR8li https://t.co/ofKRJDorIc
RRIDs were included in the Nature Communications paper "Restoration of lysosomal acidification rescues aut…" (https://t.co/QDKa7sNXc0). We appreciate the author's support of reproducibility. #RRID #methodsmatter
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
RT @LysosomeJC: Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. h…
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. https://t.co/BUHgQqVDM5