Front Endocrinol (Lausanne) May 2023 PMID 37152937

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone.

Xu Tian, Shujie Lou, Rengfei Shi

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Mentions

20
Peak: 10 in May 2023
across 2 sources since Apr 2023

Extended reach

139,799
potential audience

Total likes

4,080

Video views

70,406

Mentions per month

Apr 2023 – Oct 2025

Where it's discussed

  • X / Twitter17 posts
  • YouTube3 videos

AI synopsis

What people are saying

Discussions highlight key points from the publication, such as mitochondrial dysfunction's role in sarcopenia and how hormones like 17β-estradiol and testosterone influence this process. The tone varies from general summaries to detailed mechanistic insights, reflecting a strong interest and some engagement with the scientific content.

AgreementModerate agreement

Most discussions acknowledge the relevance of the study, with some expressing support or interest in its findings related to mitochondrial dysfunction and hormonal influences on sarcopenia.

InterestHigh interest

Participants demonstrate high interest, citing details about mechanisms and potential treatments, showing curiosity about the research implications.

EngagementModerate engagement

Posts go beyond simple acknowledgment, referencing specific mechanisms like apoptosis and mitochondrial pathways, indicating moderate depth of engagement.

ImpactModerate impact

The discourse suggests recognition of the research's importance for understanding aging-related muscle decline, though not widely calling for immediate action.

Abstract in brief

  • Sarcopenia, the age-related loss of muscle mass and strength, is linked to mitochondrial dysfunction, which involves damage to mitochondria that impair their ability to produce energy and regulate cell signals.
  • The decline in sex hormones like 17-estradiol and testosterone with age further affects mitochondrial health, as these hormones help regulate mitochondrial functions and protect against damage.
  • Understanding how mitochondrial impairments and sex hormones influence sarcopenia can lead to new treatments aimed at improving mitochondrial quality and potentially reducing muscle decline in older adults.]

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://t.co/d9xc5luRGj

May 8, 2023 · 17 likes · 6 shares · 42,324 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/Wm7Q7PdUH9

May 8, 2023 · 11 likes · 1 share · 3,932 followers View post →
htw
@heniek_htw · X

We overview current literature on key mechanisms by which #mitochondrial dysfunction contribute to development & progression of #sarcopenia & potential modulatory effects of 17β-#estradiol & #testosterone on mitochondrial function in this context

Apr 21, 2023 · 9 likes · 4 shares · 11,363 followers View post →
Frontiers - Endocrinology
@FrontEndocrinol · X

New Research: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone: Sarcopenia, characterized by a loss of muscle mass and strength with aging, is prevalent in older adults. Although the exact mechanisms underlying… https://t.co/Hr9Kp1r9m5 #Endocrinology #Endo

Apr 20, 2023 · 1 like · 5,048 followers View post →
eleanorina
@_eleanorina · X

@LWellberg that observation is from this study, 'From mitochondria to sarcopenia: role of 17β-estradiol and testosterone', ref 117, referring to their earlier work https://www.ncbi.nlm.nih[.]gov/pmc/articles/PMC10157222/ not finding trials where they were compared in a study tho :(

Feb 15, 2024 · 1 like · 3,183 followers View post →
Ruhi Snyder| systems deconstructionist| Advocate
@RuhiSleep · X

Frontiers | From mitochondria to sarcopenia: role of 17β-estradiol and testosterone The activation of apoptotic signals is accompanied by DNA fragmentation […] which eventually leads to muscle atrophy and denervation. https://t.co/ip7tZO84fD https://t.co/kUUtxbK1BY

Apr 21, 2023 · 1 like · 1,000 followers View post →

All mentions

eleanorina
@_eleanorina · X

@LWellberg that observation is from this study, 'From mitochondria to sarcopenia: role of 17β-estradiol and testosterone', ref 117, referring to their earlier work https://www.ncbi.nlm.nih[.]gov/pmc/articles/PMC10157222/ not finding trials where they were compared in a study tho :(

Feb 15, 2024 · 1 like · 3,183 followers View post →
R.A
@raan62 · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 9, 2023 · 6 shares · 186 followers View post →
Luiz Sinesio Neto
@luiz_sinesio · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 9, 2023 · 6 shares · 56 followers View post →
INGENEZ SOLUTIONS
@Ingenezkc · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 8, 2023 · 6 shares · 100 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 8, 2023 · 6 shares · 103 followers View post →
SASAKI Shota
@sasaki_lab1983 · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 8, 2023 · 6 shares · 380 followers View post →
stephen LoRusso
@stephenLoRusso2 · X

RT @CraigAGoodman1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/Wm7Q7PdUH9

May 8, 2023 · 1 share · 208 followers View post →
BillOckham
@BillOccham0 · X

RT @agingdoc1: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://…

May 8, 2023 · 6 shares · 584 followers View post →
Agingdoc
@agingdoc1 · X

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/V7DbgcnWz6 @FrontEndocrinol https://t.co/d9xc5luRGj

May 8, 2023 · 17 likes · 6 shares · 42,324 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/Wm7Q7PdUH9

May 8, 2023 · 11 likes · 1 share · 3,932 followers View post →
proteostasis_papers
@ProteostasisP · X

From mitochondria to sarcopenia: role of 17β-estradiol and testosterone https://t.co/VM3c3dpwcz https://t.co/2vpGb8jUcC

May 8, 2023 · 58 followers View post →
Swisshealthmed Dein Hormonlabor seit 2004
@Swisshealthmed · X

RT @heniek_htw: We overview current literature on key mechanisms by which #mitochondrial dysfunction contribute to development & progressio…

Apr 23, 2023 · 4 shares · 663 followers View post →
Qinlong Liu
@QinlongLiu · X

RT @heniek_htw: We overview current literature on key mechanisms by which #mitochondrial dysfunction contribute to development & progressio…

Apr 22, 2023 · 4 shares · 23 followers View post →
Isa
@isaibariat · X

RT @heniek_htw: We overview current literature on key mechanisms by which #mitochondrial dysfunction contribute to development & progressio…

Apr 21, 2023 · 4 shares · 63 followers View post →
Ruhi Snyder| systems deconstructionist| Advocate
@RuhiSleep · X

Frontiers | From mitochondria to sarcopenia: role of 17β-estradiol and testosterone The activation of apoptotic signals is accompanied by DNA fragmentation […] which eventually leads to muscle atrophy and denervation. https://t.co/ip7tZO84fD https://t.co/kUUtxbK1BY

Apr 21, 2023 · 1 like · 1,000 followers View post →
htw
@heniek_htw · X

We overview current literature on key mechanisms by which #mitochondrial dysfunction contribute to development & progression of #sarcopenia & potential modulatory effects of 17β-#estradiol & #testosterone on mitochondrial function in this context

Apr 21, 2023 · 9 likes · 4 shares · 11,363 followers View post →
Frontiers - Endocrinology
@FrontEndocrinol · X

New Research: From mitochondria to sarcopenia: role of 17β-estradiol and testosterone: Sarcopenia, characterized by a loss of muscle mass and strength with aging, is prevalent in older adults. Although the exact mechanisms underlying… https://t.co/Hr9Kp1r9m5 #Endocrinology #Endo

Apr 20, 2023 · 1 like · 5,048 followers View post →