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Nat Commun May 2023 PMID 37164975

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer.

Chenglong Sun, Anqiang Wang, Yanhe Zhou, Panpan Chen, Xiangyi Wang, Jianpeng Huang, Jiamin Gao, Xiao Wang, Liebo Shu, Jiawei Lu, Wentao Dai, Zhaode Bu, Jiafu Ji, Jiuming He

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Mentions

17
Peak: 11 in May 2023
across 4 sources since May 2023

Extended reach

31,341
potential audience

Total likes

9

Video views

38

Mentions per month

May 2023 – Aug 2023

Where it's discussed

  • X / Twitter11 posts
  • Reddit3 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

Discussions reflect strong agreement and interest, with comments praising the use of detailed molecular imaging to better understand tumor microenvironments, exemplified by phrases like 'cell-specific metabolic remodeling' and 'highlights and interactions.' Words like 'groundbreaking' and hashtags such as #highlights and #metabolomics indicate a high perceived impact and engagement from the scientific community.

AgreementModerate agreement

Most discussions express positive acknowledgment of the study’s significance, emphasizing its contributions to understanding tumor biology and potential treatments.

InterestHigh interest

The discussions demonstrate high curiosity and enthusiasm, with multiple mentions highlighting the innovative methodology and implications.

EngagementModerate engagement

Participants reference specific aspects such as cell interactions, metabolic remodeling, and advanced techniques, showing thoughtful engagement.

ImpactHigh impact

The overall tone suggests that the publication is seen as impactful, potentially influencing future cancer research and theranostics.

Abstract in brief

  • Mapping tumor metabolic changes and their interactions with surrounding non-tumor cells enhances our understanding of tumor biology and informs new treatment strategies.
  • This study combines mass spectrometry imaging and microarray-based transcriptomics to visualize metabolic differences and cell interactions in gastric cancer samples.
  • The findings reveal a complex tumor microenvironment, highlighting areas where tumor cells meet healthy tissue and showing unique immune and metabolic changes that could influence cancer treatment approaches.
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Top posts

Most liked on X and Bluesky
Kermit Murray
@kermitmurray · X

(Nature MS) Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (RSS) #nature #MassSpec https://t.co/gl18AFUWtA https://t.co/MKyrtyeUIt

May 10, 2023 · 3 likes · 2 shares · 1,970 followers View post →
Metabolomics Papers
@Metabbot · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun #metabolomics https://t.co/mfeg3Ed0Kz

May 11, 2023 · 3 likes · 2 shares · 1,489 followers View post →
Reddit Journal of Science
@rsciencejournal · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (May 2023) https://t.co/quR8PfmRNZ #science #cancer #multiomics #highlights #remodeling #interactions

May 14, 2023 · 2 likes · 1 share · 334 followers View post →
BioMassSpec
@realBioMassSpec · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer #NatCommun #MassSpec https://t.co/n3A8qZBoEb

May 11, 2023 · 1 like · 5,994 followers View post →
Bioinformatics Trends 
@BinfoTrends · X

RT @Metabbot: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun #…

May 11, 2023 · 2 shares · 8,159 followers View post →
Bioinformatics Trends 
@BinfoTrends · X

RT @rsciencejournal: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (May 2…

May 14, 2023 · 1 share · 8,159 followers View post →

All mentions

Bioinformatics Trends 
@BinfoTrends · X

RT @rsciencejournal: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (May 2…

May 14, 2023 · 1 share · 8,159 followers View post →
Reddit Journal of Science
@rsciencejournal · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (May 2023) https://t.co/quR8PfmRNZ #science #cancer #multiomics #highlights #remodeling #interactions

May 14, 2023 · 2 likes · 1 share · 334 followers View post →
Roozbeh Eskandari
@roeskandari · X

RT @Metabbot: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun #…

May 11, 2023 · 2 shares · 232 followers View post →
Transcriptomes
@transcriptomes · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions... https://t.co/q35WsNAbkX

May 11, 2023 · 1,808 followers View post →
Bioinformatics Trends 
@BinfoTrends · X

RT @Metabbot: Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun #…

May 11, 2023 · 2 shares · 8,159 followers View post →
Metabolomics Papers
@Metabbot · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun #metabolomics https://t.co/mfeg3Ed0Kz

May 11, 2023 · 3 likes · 2 shares · 1,489 followers View post →
BioMassSpec
@realBioMassSpec · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer #NatCommun #MassSpec https://t.co/n3A8qZBoEb

May 11, 2023 · 1 like · 5,994 followers View post →
k____i
@k____i · X

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer https://t.co/8u0asMdycF #nature #feedly

May 10, 2023 · 226 followers View post →
Imaging MS Society
@IMSSNews · X

RT @kermitmurray: (Nature MS) Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric canc…

May 10, 2023 · 2 shares · 2,325 followers View post →
Andrea Petretto
@Angrist_Fusion · X

RT @kermitmurray: (Nature MS) Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric canc…

May 10, 2023 · 2 shares · 580 followers View post →
Kermit Murray
@kermitmurray · X

(Nature MS) Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer (RSS) #nature #MassSpec https://t.co/gl18AFUWtA https://t.co/MKyrtyeUIt

May 10, 2023 · 3 likes · 2 shares · 1,970 followers View post →