Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/pZAWehzJ8M
Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain.
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Mar 2023 – Mar 2025Where it's discussed
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X / Twitter84 posts
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News16 articles
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Blogs2 articles
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Bluesky1 posts
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YouTube1 videos
AI synopsis
What people are saying
Many discussions highlight the potential of targeting oligomeric tau for therapeutic strategies in Alzheimer's disease. For instance, phrases like 'promising therapeutic strategy' and 'another endorsement for the prion-like spread of tau' display an encouraging and optimistic tone about the research's implications. This choice of wording and the enthusiastic tone contribute to the overall positive sentiment and signify a recognition of the potential benefits in Alzheimer's research.
Many posts express support for the findings and their implications for understanding Alzheimer's pathology.
The audience shows a high level of curiosity about the research topic, evidenced by various discussions and inquiries into the findings.
While some posts are casual, several engage with specific details from the research, suggesting a moderate depth of engagement.
There is a consensus that the findings could significantly impact Alzheimer's research and treatment strategies.
Abstract in brief
- Oligomeric tau is found at pre and postsynaptic terminals in human Alzheimer's brains, even in areas without significant fibrillar tau.
- Research indicates that this form of tau could be responsible for synaptic damage and may contribute to Alzheimer's pathology by spreading between neurons.
- Targeting and reducing oligomeric tau at synapses might be an effective therapeutic approach to combat the disease.
Top posts
Most liked on X and BlueskyADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプスへのタウの伝播を確認。 https://t.co/6JUWUOgCZr
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain: https://t.co/S76FuPRcNg
By all accounts @TSpiresJones brought the house down with her keynote at Alzheimer's Association International Conference on Weds! Well done to Tara & team!
All mentions
Targeting Oligomeric Tau for Alzheimer’s Disease Therapy
This video explores how oligomeric tau is found in Alzheimer's-affected brains, highlighting its role in synaptic damage and disease progression. It discusses potential therapeutic strategies for targeting oligomeric…
RT @EdinUniNeuro: By all accounts @TSpiresJones brought the house down with her keynote at Alzheimer's Association International Conference…
By all accounts @TSpiresJones brought the house down with her keynote at Alzheimer's Association International Conference on Weds! Well done to Tara & team!
Interestingly, entorhinal hAPP-induced hyperexcitability was quelled by co-expression of human Tau, at the expense of increased pathological tau species, especially oligomeric tau (experiment inspired by this recent paper from the group of @TSpiresJones): https://t.co/s7V9Ra8SRl
Dementia study reveals how toxic proteins spread through brain https://t.co/fRWyt5UM8U https://t.co/oCa7bVURG4 https://t.co/hukbhTtuaq
RT @ScienceQueers: Selecció de notícies científiques compartides a la llista de l'@ACCC_: supernoves, diagnosi mèdica amb biaix, neurologia…
RT @ScienceQueers: Selecció de notícies científiques compartides a la llista de l'@ACCC_: supernoves, diagnosi mèdica amb biaix, neurologia…
Selecció de notícies científiques compartides a la llista de l'@ACCC_: supernoves, diagnosi mèdica amb biaix, neurologia, biodiversitat i plàstic. Vídeo
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/NUhE2g95K1
RT @mom_neurosci: ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプス…
RT @mom_neurosci: ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプス…
RT @mom_neurosci: ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプス…
RT @mom_neurosci: ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプス…
RT @mom_neurosci: ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプス…
ADの剖検脳をsub-diffraction-limit microscopyで観察したところ、タウオリゴマーがシナプスに蓄積。NFTがあまり多くない細胞でもタウオリゴマーのシナプス蓄積が見られた。 P301Sマウスでは、プレ→ポストシナプスへのタウの伝播を確認。 https://t.co/6JUWUOgCZr
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain #neuropath https://t.co/mfpIq4TQXo
RT @MASogorb: Descubren cómo las proteínas tóxicas se propagan por el cerebro en la enfermedad de Alzheimer https://t.co/DEC5Okhdhq Más inf…
Descubren cómo las proteínas tóxicas se propagan por el cerebro en la enfermedad de Alzheimer https://t.co/DEC5Okhdhq Más información: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/zbWCcI0Uf0
..reducing oligomeric tau at synapses as a promising therapeutic strategy for Alzheimer’s disease.. https://t.co/fwN84m4U2u
RT @thmonk_pf: 超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomer…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain - ScienceDirect https://t.co/9LTn7kTxr5
RT @thmonk_pf: 超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomer…
RT @thmonk_pf: 超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomer…
RT @thmonk_pf: 超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomer…
RT @thmonk_pf: 超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomer…
超高解像度顕微鏡(sub-diffraction-limit microscopy)を用いてADのsynapseにおけるtauを解析 皮質synapseには燐酸化tauやmisfold tauよりもtau oligomerが多く、oligomerはtangleの無い領域にも存在 tau oligomerはsynapseを通して拡散していく #tau #synapse #papers https://t.co/Vlyh3ldRwy https://t.co/AU61U5LVdd
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
[Neuron] Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain https://t.co/arR8GjRlXe
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain #neuropath https://t.co/np19eRmkK9
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain by Martí Colom-Cadena https://t.co/NOgOAIHpnN
Another endorsement for the prion-like spread of tau in Alzheimer’s, from the team at Hospital Sant Pau, Barcelona. Congrats https://t.co/HxaYoDOHYg
RT @IIBSantPau:
RT @Pluchinolab: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain: Neu…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @IIBSantPau:
RT @IIBSantPau:
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/KbutNrIiM0
RT @IIBSantPau:
RT @IIBSantPau:
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @IIBSantPau:
RT @IIBSantPau:
RT @IIBSantPau:
RT @IIBSantPau:
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain: Neuron https://t.co/Uua5kDNY7j
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/hgKWnFZ5Hf
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
RT @LukensJohnR: Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain http…
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain: https://t.co/S76FuPRcNg
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain https://t.co/pZAWehzJ8M
Synaptic oligomeric tau in Alzheimer's disease - a potential culprit in the spread of tau pathology through the brain https://t.co/Qvn7cAxpZC
RT @TaraTracyLab: Synaptic oligomeric tau in Alzheimer's disease - a potential culprit in the spread of tau pathology through the brain htt…
Synaptic oligomeric tau in Alzheimer's disease - a potential culprit in the spread of tau pathology through the brain https://t.co/EpqrKCbo3T
Synaptic oligomeric tau in Alzheimer's disease - a potential culprit in the spread of tau pathology through the brain https://t.co/6Es6snJDzs #medRxiv