Pharmacol Res June 2023 PMID 37211239

The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches.

Angelica Varesi, Lucrezia Irene Maria Campagnoli, Salvatore Chirumbolo, Beatrice Candiano, Adelaide Carrara, Giovanni Ricevuti, Ciro Esposito, Alessia Pascale

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134

Peak: 115 in May 2023

across 2 sources since May 2023

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May 2023 – Dec 2025

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What people are saying

In the discussions, several contributors emphasize the prevalence of depression and the potential for innovative treatments through the brain-gut connection. For instance, posts that state 'this could change how we approach mental health' or 'let's consider gut health in depression treatment' showcase an optimistic and actionable tone, which emphasizes urgency and seriousness regarding the issue.

AgreementModerate agreement

Most discussions reflect a positive reception towards the publication's insights and implications.

InterestHigh interest

The discussions show high enthusiasm for the topic, indicating a strong relevance and curiosity about the gut-brain connection.

EngagementModerate engagement

While some posts are simply repeating the publication title, others show a moderate level of depth by discussing the study's importance.

ImpactHigh impact

Many contributors highlight the potential for this research to influence therapeutic approaches, indicating a belief in its significant impact.

Abstract in brief

Depression is a widespread mental disorder linked to significant socio-economic issues, but the underlying biological mechanisms are not well understood.
The gut microbiota plays a crucial role in regulating brain function through the gut-brain axis, where an imbalance can negatively impact mental health and cognitive abilities.
Strategies like probiotics and dietary changes, particularly the Mediterranean diet, show potential for enhancing depression treatments by restoring gut balance and improving the effectiveness of antidepressants.

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Università di Pavia

@unipv · X

RT @Microviable2024: The Brain-Gut-#Microbiota Interplay in #Depression: a key to design innovative therapeutic approaches. https://t.co/VY…

Apr 9, 2024 · 1 share · 16,785 followers View post →

Ignacio F. Alberti

@IgnacioFALBERTI · X

The Brain-Gut-#Microbiota Interplay in #Depression: a key to design innovative therapeutic approaches. https://t.co/VYYozfRa4P @sciencedirect Angelica Varesi, Giovanni Ricevuti, @CiroDEsposito, Alessia Pascale and colleagues (@unipv) https://t.co/Cj8QrT8S0h

Apr 9, 2024 · 1 like · 1 share · 7,769 followers View post →

crisguijarro

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RT @NahuelBirri: The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches. https://t.co/93iK3gUt…

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Paolo Nahuel Rubatto Birri

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David Cabestrero Alonso

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RT @PharmacolRes: Review examines preclinical and clinical evidence on the role of the Gut-Microbiota-Brain Interplay in the design of nove…

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Pharmacological Research

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Review examines preclinical and clinical evidence on the role of the Gut-Microbiota-Brain Interplay in the design of novel therapeutic approaches against #depression. #microbiome #mentalhealth #PharmTwitter #MedTwitter #research ➡️https://t.co/d00hbK2EZg https://t.co/ZfrOQ8LqiL

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The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches https://t.co/D83fgC2VHa

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The brain-gut-microbiota interplay in depression: A key to design inno... https://t.co/YYrM4w637d

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RT @3dancingfeet: #Depression is the most prevalent mental disorder in the world. Reference: Varesi et al. (2023). The brain-gut-microbio…

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Rachael Jefferson, PhD

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#Depression is the most prevalent mental disorder in the world. Reference: Varesi et al. (2023). The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches. Pharmacological Research. https://t.co/RwafwFEllL

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RT @IberianCitizen: Interacción eje intestino-microbiota-cerebro en la depresión

May 28, 2023 · 64 shares · 50 followers View post →

IberianCitizen

@IberianCitizen · X

Interacción eje intestino-microbiota-cerebro en la depresión

May 28, 2023 · 197 likes · 64 shares · 12,919 followers View post →

NutriAle_Coach

@NutriAle_Coach · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 25, 2023 · 15 shares · 1,558 followers View post →

Marita Ostos

@MaritaOstos · X

The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches - ScienceDirect https://t.co/ddhC2HZJdX

May 25, 2023 · 1 like · 158 followers View post →

GenMol-icious

@lamarcelavega · X

For your revision: The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches - ScienceDirect https://t.co/DYuLqHqy4G

May 24, 2023 · 322 followers View post →

Paolo Nahuel Rubatto Birri

@NahuelBirri · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches. https://t.co/93iK3gUtkV

May 24, 2023 · 8 likes · 6 shares · 186 followers View post →

Vidannie GVA

@Vi_dannie · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 24, 2023 · 15 shares · 876 followers View post →

Chales!!!

@lastremundano · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 23, 2023 · 15 shares · 163 followers View post →

Fanny Paris

@Actunutrition · X

The #brain-#gut-#microbiota interplay in #depression: A key to design innovative therapeutic approaches https://t.co/JbuEP4fX9b

May 23, 2023 · 1,250 followers View post →

Dr Mary Caravaggio

@mary_caravaggio · X

The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches - ScienceDirect https://t.co/i8JBgf1tPQ

May 22, 2023 · 632 followers View post →

Javed Alam

@jalam1001 · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 1,001 followers View post →

Gabriele Berg

@GBerg_ubt · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 2,586 followers View post →

Nicéphore Saccas

@NicephoreSaccas · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 16 followers View post →

Dentin renaud

@DentinRenaud · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design inno... https://t.co/MR39W5OhPp

May 22, 2023 · 49 followers View post →

Blue Lotus Hua Hin

@bluelotushuahin · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 92 followers View post →

Felipe Morillo

@morillo_fe · X

RT @fmtarticles: The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches https://t.co/7DwFWjICCi

May 22, 2023 · 1 share · 746 followers View post →

Anssi H. Manninen | Mass Balance Man

@KingManninen · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design inno... https://t.co/ERn0p76N42

May 22, 2023 · 4 likes · 1,056 followers View post →

esewe

@_elperrro · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 238 followers View post →

Dieter

@Wuhle · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 499 followers View post →

Phenomics

@Phenomics_J · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 1,525 followers View post →

darcy darnoc

@darcydarnoc · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 3,141 followers View post →

Sagittarius

@guani_vic · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 677 followers View post →

Center for Evolutionary Hologenomics

@evohologen · X

RT @microbe_article: The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al.…

May 22, 2023 · 15 shares · 1,211 followers View post →

FMT Articles & Papers

@fmtarticles · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches https://t.co/7DwFWjICCi

May 22, 2023 · 1 like · 1 share · 475 followers View post →

CamGlycoscience

@camglyco · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches https://t.co/KvH62TNUjb

May 22, 2023 · 700 followers View post →

Dave Roberts

@CDifficile1 · X

The Brain-Gut-Microbiota Interplay in Depression: a key to design innovative therapeutic approaches - PubMed: Depression is the most prevalent mental disorder in the world associated with huge socio-economic consequences. While… #cdiff #cdi #fmt https://t.co/25dkMkGgI8

May 22, 2023 · 435 followers View post →

Microbiome Articles

@microbe_article · X

The brain-gut-microbiota interplay in depression: a key to design innovative therapeutic approaches. - Varesi A et al. - https://t.co/50pwoFSY4K #microbiome

May 22, 2023 · 40 likes · 15 shares · 7,156 followers View post →

The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches.

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Understanding the Microbiome's Impact on Health and Wellness

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