PLoS Med May 2023 PMID 37216385

Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: A cluster-randomized trial (The TUTT Trial).

Neil A Martinson, Bareng A S Nonyane, Leisha P Genade, Rebecca H Berhanu, Pren Naidoo, Zameer Brey, Anthony Kinghorn, Sipho Nyathi, Katherine Young, Harry Hausler, Lucy Connell, Keeren Lutchminarain, Khine Swe Swe-Han, Helena Vreede, Mohamed Said

Download social card

Mentions

19
Peak: 3 in May 2023
across 3 sources since May 2023

Extended reach

70,470
potential audience

Total likes

2

Video views

23

Mentions per month

May 2023 – Sep 2023

Where it's discussed

  • News14 articles
  • X / Twitter4 posts
  • YouTube1 videos

AI synopsis

What people are saying

The social discussions reflect an interest in the study's focus on high-risk populations like those living with HIV and contact history, with some posts highlighting the trial's relevance to screening strategies. The tone suggests careful analysis rather than strong agreement or disagreement, as they emphasize understanding the results and their implications for TB testing policies.

AgreementModerate agreement

Most discussions reflect a generally positive or neutral view of the study, recognizing its focus and findings without strong disagreement.

InterestModerate interest

The posts demonstrate moderate interest, especially through discussions about high-risk groups, HIV, and TB contacts, indicating engagement with the topic.

EngagementModerate engagement

Comments include references to the methodology and implications, showing a moderate level of thoughtfulness, but lack deep critical analysis or extensive debate.

ImpactModerate impact

The discussions acknowledge the significance of universal testing approaches and their limited increased yield, pointing to a moderate perceived impact on public health strategies.

Abstract in brief

  • The TUTT trial investigated whether targeted universal testing (TUTT) for tuberculosis (TB) in high-risk groups could diagnose more TB cases in South African primary care clinics than the standard symptom-based testing approach.
  • The study involved 62 clinics and was halted early due to COVID-19 restrictions, but it still found similar numbers of TB diagnoses in both intervention and control groups.
  • Overall, the findings suggest that targeting high-risk groups for universal TB testing did not significantly increase the number of TB cases diagnosed compared to the standard symptom-driven testing method.

Top posts

Most liked on X and Bluesky
PLOS Medicine
@PLOSMedicine · X

In a cluster randomised trial of primary care clinics in South Africa, Neil Martinson and colleagues, investigate the value of targeted testing for Tuberculosis in those at highest risk. https://t.co/cghhy8C1cd https://t.co/pdxdNM3BVP

Jun 6, 2023 · 2 likes · 58,015 followers View post →
Stigmabase | ORG
@StigmabaseO · X

RT @StigmabaseO: [HIV-ZA] Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In int…

May 27, 2023 · 1 share · 4,143 followers View post →
Stigmabase | ORG
@StigmabaseO · X

[HIV-ZA] Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In intervention clinics, attendees living with HIV, those self-reporting a recent close contact with TB, or a prior episode of TB were all… https://t.co/nXtOPR25Vn

May 25, 2023 · 1 share · 4,143 followers View post →
Stigmabase | ORG
@StigmabaseO · X

HIV Fighting Stigma} Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In intervention clinics, attendees living with HIV, those self-reporting a recent close contact with TB, or a prior episode of… https://t.co/SynVVKuQfp

May 22, 2023 · 4,143 followers View post →

All mentions

PLOS Medicine
@PLOSMedicine · X

In a cluster randomised trial of primary care clinics in South Africa, Neil Martinson and colleagues, investigate the value of targeted testing for Tuberculosis in those at highest risk. https://t.co/cghhy8C1cd https://t.co/pdxdNM3BVP

Jun 6, 2023 · 2 likes · 58,015 followers View post →
Stigmabase | ORG
@StigmabaseO · X

RT @StigmabaseO: [HIV-ZA] Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In int…

May 27, 2023 · 1 share · 4,143 followers View post →
Stigmabase | ORG
@StigmabaseO · X

[HIV-ZA] Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In intervention clinics, attendees living with HIV, those self-reporting a recent close contact with TB, or a prior episode of TB were all… https://t.co/nXtOPR25Vn

May 25, 2023 · 1 share · 4,143 followers View post →
Stigmabase | ORG
@StigmabaseO · X

HIV Fighting Stigma} Evaluating systematic targeted universal testing for tuberculosis in primary care clinics of South Africa: In intervention clinics, attendees living with HIV, those self-reporting a recent close contact with TB, or a prior episode of… https://t.co/SynVVKuQfp

May 22, 2023 · 4,143 followers View post →