BMC Med May 2023 PMID 37226271

The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial.

Jia Sun, Yuting Ruan, Ningning Xu, Peili Wu, Nie Lin, Kun Yuan, Shengli An, Pei Kang, Shu Li, Qiya Huang, Yingzhang, Yuzhong Li, Jialin Su, Wenjun Ma, Bo Chen

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Mentions

35
Peak: 8 in May 2023
across 4 sources since May 2023

Extended reach

239,175
potential audience

Total likes

186

Video views

5,340

Mentions per month

May 2023 – Sep 2025

Where it's discussed

  • X / Twitter26 posts
  • YouTube4 videos
  • News3 articles
  • Reddit2 posts

AI synopsis

What people are saying

Discussions exemplify a balanced curiosity and analytical tone, with posters referencing historical figures like Hippocrates and comparing the trial’s results with other studies such as PREDIMED. Phrases like 'most potent' and references to 'evidence' convey a respectful acknowledgment of the research's potential, but comments also include skepticism about overgeneralizing its implications, reflecting moderate engagement and perceived impact.

AgreementModerate agreement

Most discussions acknowledge the study's findings, with some highlighting the effectiveness of low-carb and calorie restriction strategies supported by the research.

InterestModerate interest

Posts indicate moderate curiosity, with individuals referencing historical and contemporary evidence and questioning various dietary approaches.

EngagementModerate engagement

Comments often analyze the study design and compare it with other research, suggesting a willingness to interpret and critique the findings.

ImpactModerate impact

While some posts imply that the study could influence dietary approaches or validate certain methods, overall, there is cautious optimism rather than a belief in a paradigm-shifting discovery.

Top posts

Most liked on X and Bluesky
DoctorTro
@DoctorTro · X

https://t.co/IQZs77RrIK https://t.co/VNscQO50lS

Jun 2, 2023 · 32 likes · 1 share · 161,260 followers View post →
Agingdoc
@agingdoc1 · X

The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial "The combination of restricting carbohydrate and total calorie intake may augment the beneficial effects of https://t.co/26sS70a3YO

May 25, 2023 · 14 likes · 5 shares · 41,610 followers View post →
クロマッキー | 著書『「やせる本」100冊のダイエットのコツを1冊にまとめてみた。』
@Chromakkey · X

バランスの取れたカロリー制限より、低炭水化物+カロリー制限の方が同じ期間でより痩せられることを示唆した2023年のランダム化比較試験です

May 5, 2024 · 2 likes · 1,593 followers View post →
Whitfield Lewis, MD
@whitfieldlewis6 · X

@ItIsMikeFitz @rf121rf @thelowcarb_rd @christygh Dropping this here. There is a lot of evidence in favor of therapeutic carbohydrate restriction. Even Hippocrates and Galen knew sugars and low-fiber starches were fattening. The concept of the fattening carbohydrates dates back to over 2,000 years. https://t.co/jJ29SZmD7h

Apr 15, 2025 · 1 like · 3,433 followers View post →
Older-Stronger-Faster
@Strong_Old_Men · X

https://t.co/XU8qMFdHOK

Mar 8, 2025 · 1 like · 1,646 followers View post →
KapaiKiwi
@kapaibro · X

@EnlightenedAKV https://t.co/9w9A4minvM https://t.co/URjYamL54Y https://t.co/i6gmcAleEb

Feb 8, 2024 · 1 like · 1,061 followers View post →

All mentions

AP Joshua
@Metabolic1992 · X

@ScottAppliedSci Low carb + controlled calories is the most potent. https://t.co/QAcbwUDRIS

Sep 10, 2025 · 364 followers View post →
Whitfield Lewis, MD
@whitfieldlewis6 · X

@grok @reallyoptimized What about PREDIMED? They consumed more fish and less carbohydrates. Other studies: Sun, J., Ruan, Y., Xu, N. et al. The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled

Aug 12, 2025 · 3,433 followers View post →
Whitfield Lewis, MD
@whitfieldlewis6 · X

@ItIsMikeFitz @rf121rf @thelowcarb_rd @christygh Dropping this here. There is a lot of evidence in favor of therapeutic carbohydrate restriction. Even Hippocrates and Galen knew sugars and low-fiber starches were fattening. The concept of the fattening carbohydrates dates back to over 2,000 years. https://t.co/jJ29SZmD7h

Apr 15, 2025 · 1 like · 3,433 followers View post →
Older-Stronger-Faster
@Strong_Old_Men · X

https://t.co/XU8qMFdHOK

Mar 8, 2025 · 1 like · 1,646 followers View post →
Kyle Glazier
@kyleglazier · X

@FitFastCoach Lots of useless information for weight loss in this thread, Rueben. Your gut is going to be happier (less enflamed) when your fat ass stops consuming so many excess calories: https://t.co/O406rFFIKV https://t.co/xz0ee6rWLK Weight loss has been solved long ago. If you're eating

Jan 11, 2025 · 135 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@renedumbra @joejfamous @DrEenfeldt @BenBikmanPhD That’s also not true. There was a randomized controlled trial in 2023 that precisely sought to answer this question. Protein was 20% for both groups and the LCHF actually consumed MORE calories. Can you guess the results ? https://t.co/x2GykJKqlN.

Dec 27, 2024 · 264 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@JesperLundbom @shivadas29 @DrEenfeldt When you have strict carb restriction (<50 g a day) and even this is ongoing for at least 3 months (enough time for hormonal effects to take place), you will have the benefits of carb restriction. https://t.co/HSbQIQ2pRl

Dec 1, 2024 · 264 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@deportriggers @DoddGarger @MichaelAlbertMD Here is the trial you requested. This is an RCT involving a VLCD without caloric restriction versus a caloric restricted standard diet. In fact, the VLCD had MORE calories and patients still lose MORE weight. https://t.co/g6T5Cg8N9O

Oct 28, 2024 · 264 followers View post →
クロマッキー | 著書『「やせる本」100冊のダイエットのコツを1冊にまとめてみた。』
@Chromakkey · X

バランスの取れたカロリー制限より、低炭水化物+カロリー制限の方が同じ期間でより痩せられることを示唆した2023年のランダム化比較試験です

May 5, 2024 · 2 likes · 1,593 followers View post →
KapaiKiwi
@kapaibro · X

@EnlightenedAKV https://t.co/9w9A4minvM https://t.co/URjYamL54Y https://t.co/i6gmcAleEb

Feb 8, 2024 · 1 like · 1,061 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@renatodumbra @ted_ryce @ChrisStraga https://t.co/g6T5Cg8fkg

Jun 7, 2023 · 264 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@ted_ryce https://t.co/rRPjNg0N1H

Jun 6, 2023 · 264 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@nuclearmed23 @ted_ryce https://t.co/GVmoXzl6qm

Jun 5, 2023 · 264 followers View post →
Thelast Stylebender
@ThelastStyleb16 · X

@nuclearmed23 @ted_ryce https://t.co/CFRwTdesDb

Jun 5, 2023 · 264 followers View post →
Earthling Bob
@EarthlingAus · X

Who's good at analysing studies? What's your interpretation of the 12 week effect of low-carb on LDL-C levels compared to the other groups? https://t.co/hLNbPJjdXR https://t.co/JKwALcUKQi

Jun 3, 2023 · 865 followers View post →
Skier’s Right
@SkiersRight · X

RT @DoctorTro: https://t.co/IQZs77RrIK https://t.co/VNscQO50lS

Jun 2, 2023 · 1 share · 810 followers View post →
DoctorTro
@DoctorTro · X

https://t.co/IQZs77RrIK https://t.co/VNscQO50lS

Jun 2, 2023 · 32 likes · 1 share · 161,260 followers View post →
健康ノート
@JuStADOcToR_Jp · X

The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial - PMC https://t.co/q4RrGTfBn9

Jun 2, 2023 · 110 followers View post →
Lukas
@Morluk76 · X

RT @agingdoc1: The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a…

May 28, 2023 · 5 shares · 215 followers View post →
ACHS Research
@AchsResearch · X

New NUTRITION Research Available. Click Here to Access Article(s): https://t.co/mGJ4qzbemq

May 26, 2023 · 44 followers View post →
BMC Medicine
@BMCMedicine · X

Jia Sun, Yuting Ruan, Ningning Xu and colleagues assess the impact of a dietary restriction on weight and metabolic health in overweight individuals. Read the full study here: https://t.co/0PiqEvBL1e https://t.co/QeMwhWHcxV

May 26, 2023 · 9,197 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a…

May 25, 2023 · 5 shares · 131 followers View post →
Armen Minasian
@ArmenMinasian3 · X

RT @agingdoc1: The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a…

May 25, 2023 · 5 shares · 23 followers View post →
Dr Kevin Lee
@dr_kevinlee · X

RT @agingdoc1: The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a…

May 25, 2023 · 5 shares · 5,447 followers View post →
Agingdoc
@agingdoc1 · X

The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial "The combination of restricting carbohydrate and total calorie intake may augment the beneficial effects of https://t.co/26sS70a3YO

May 25, 2023 · 14 likes · 5 shares · 41,610 followers View post →
MyJournals
@myjournals · X

The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial https://t.co/kTvRryrJzT

May 24, 2023 · 557 followers View post →