https://t.co/H5dHDNDAta 腸内細菌叢代謝物のCRC(大腸癌)⬆️ 胆汁酸(DCA,LCA等),trimethylamine n-oxide(TMAO)等の代謝物は癌細胞の増殖,DNA損傷⬆️, 腫瘍の浸潤と転移の促進,細胞間接着⬇️, ゲノム不安定性の促進でCRC発症を促進 *油もの,甘い糖質過多,飲酒過多→肝胆に負担 →尿,便が黄色:要注意 https://t.co/W7GmsXXxT1
Role of the Gut Microbiota and Its Metabolites in Tumorigenesis or Development of Colorectal Cancer.
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Nov 2022 – Sep 2024Where it's discussed
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YouTube5 videos
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X / Twitter3 posts
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Bluesky1 posts
AI synopsis
What people are saying
The discussions highlight the importance of bacteria such as Fusobacterium nucleatum and metabolites like butyrate, with some posts mentioning how dietary changes might influence CRC risk, illustrating a balanced mix of recognition, curiosity, and thoughtful engagement based on the tone and specific scientific references.
Most discussions acknowledge the crucial role of gut bacteria and their metabolites in CRC development, reflecting general agreement with the publication's findings.
The posts show modest curiosity, with some expressing enthusiasm about the potential therapeutic implications but not deeply exploring the topic.
Participants reference mechanisms, specific bacteria, and metabolites, indicating a moderate level of detailed engagement.
Comments hint at the significance of microbiota research for future CRC treatments, suggesting awareness of its potential influence.
Abstract in brief
- The gut microbiota, which resides in the intestines, interacts with the host and influences the development of colorectal cancer (CRC), with certain bacteria promoting or protecting against the disease.
- Specific bacteria like Fusobacterium nucleatum and Escherichia coli are linked to promoting CRC, while others such as Clostridium butyricum may have protective effects, and these microbial patterns can vary in early-onset CRC cases.
- Metabolites produced by gut bacteria, including harmful substances like primary bile acids and beneficial compounds like butyrate, play significant roles in CRC development, diagnosis, and treatment, offering potential targets for future therapies.]
Top posts
Most liked on X and BlueskyRole of the Gut Microbiota and Its Metabolites in Tumorigenesis or Development of Colorectal Cancer https://t.co/YZvlxS3CYC
Role of the Gut Microbiota and Its Metabolites in Tumorigenesis or Development of Colorectal Cancer https://t.co/x1GxOYvSQD https://t.co/0MvbSxeyEQ
Human gut homeostasis and regeneration: the role of the gut microbiota and its metabolites @pauldcotter @teagasc @Pharmabiotic https://www.tandfonline.com/doi/full/10.1080/1040841X.2022.2142088
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https://t.co/H5dHDNDAta 腸内細菌叢代謝物のCRC(大腸癌)⬆️ 胆汁酸(DCA,LCA等),trimethylamine n-oxide(TMAO)等の代謝物は癌細胞の増殖,DNA損傷⬆️, 腫瘍の浸潤と転移の促進,細胞間接着⬇️, ゲノム不安定性の促進でCRC発症を促進 *油もの,甘い糖質過多,飲酒過多→肝胆に負担 →尿,便が黄色:要注意 https://t.co/W7GmsXXxT1
Role of the Gut Microbiota and Its Metabolites in Tumorigenesis or Development of Colorectal Cancer https://t.co/x1GxOYvSQD https://t.co/0MvbSxeyEQ
Role of the Gut Microbiota and Its Metabolites in Tumorigenesis or Development of Colorectal Cancer https://t.co/YZvlxS3CYC
Human gut homeostasis and regeneration: the role of the gut microbiota and its metabolites @pauldcotter @teagasc @Pharmabiotic https://www.tandfonline.com/doi/full/10.1080/1040841X.2022.2142088