PubHawk
PLoS Negl Trop Dis June 2023 PMID 37267343

High frequency of Voltage-gated sodium channel (VGSC) gene mutations in Aedes albopictus (Diptera: Culicidae) suggest rapid insecticide resistance evolution in Shanghai, China.

Hao Yuan, Wenqi Shan, Yuhang Zhang, Hanlu Yan, Yikai Li, Qiuming Zhou, Haowei Dong, Feng Tao, Hongxia Liu, Peien Leng, Heng Peng, Yajun Ma

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Mentions

2
Peak: 1 in Jun 2023
across 2 sources since Jun 2023

Extended reach

1,048
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Jun 2023 – Sep 2023

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AI synopsis

What people are saying

The overall discussion reflects an acknowledgment of the article's importance, with posts mentioning the genetic mutations such as V1016G and F1534C and their role in resistance, showing curiosity and concern. The tone is informative yet cautious, emphasizing the potential challenges for mosquito control efforts and public health, which indicates a moderate to high perceived impact of the findings.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, highlighting the high mutation frequency and its implications for insecticide resistance.

InterestModerate interest

Participants show moderate interest, often discussing the genetic findings but not deeply exploring potential solutions or broader impacts.

EngagementModerate engagement

The discussions include references to specific mutations like V1016G and F1534C, indicating some engagement with the scientific details, but generally remain surface-level.

ImpactModerate impact

Many recognize the importance of the findings for public health and mosquito control, considering the genetic diversity as a major concern for future strategies.

Abstract in brief

  • The study found a high frequency (84.65%) of mutations in the VGSC gene of Aedes albopictus mosquitoes in Shanghai, which suggests rapid development of insecticide resistance, especially to pyrethroids.
  • Several specific mutations, including V1016G, I1532T, and F1534C, were identified, with some being reported in Shanghai for the first time, indicating ongoing genetic changes in mosquito populations.
  • The presence of different intron types in the VGSC gene and their association with certain mutations suggest genetic diversity that could influence resistance evolution, complicating efforts to control mosquito populations and prevent dengue fever.]
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DNA nanotech papers
@dnananopapers · X

High frequency of Voltage-gated sodium channel (VGSC) gene mutations in Aedes albopictus (Diptera: Culicidae) suggest rapid insecticide resistance evolution in Shanghai, China https://t.co/bV5Rm4GUtL

Jun 5, 2023 · 999 followers View post →

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DNA nanotech papers
@dnananopapers · X

High frequency of Voltage-gated sodium channel (VGSC) gene mutations in Aedes albopictus (Diptera: Culicidae) suggest rapid insecticide resistance evolution in Shanghai, China https://t.co/bV5Rm4GUtL

Jun 5, 2023 · 999 followers View post →