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Overall, discussions reflect a positive reception with posts emphasizing the role of CARD8 in detecting coronaviruses and picornaviruses, such as mentioning genetic polymorphisms that alter immune responses. The tone ranges from scientific to hopeful, as seen in phrases like 'broad sensor' and 'host-specific sensing,' highlighting potential avenues for therapeutic research and understanding individual differences in viral susceptibility.
Most discussions support the research findings, emphasizing the significance of CARD8 in viral sensing and acknowledging the genetic factors involved.
The topic sparks high interest, with many posts highlighting the novelty of immune sensing mechanisms and potential implications for understanding COVID-19 resistance.
Posts demonstrate moderate engagement, referencing specific viral mechanisms, genetic variations, and scientific experiments, indicating interested but not deeply technical discussions.
The discussions suggest the research could influence future studies on immune responses and viral infection susceptibility, though broad societal or medical impacts are implied rather than explicitly discussed.
Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out in @PLOSBiology ! https://t.co/7ro2yhrzVs…Huge congratulations to all involved! More info and thanks to our many collaborators are in the thread below: https://t.co/KIdjQdxO0A
Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M https://t.co/BoHIY2u5RF
Great talk by the @Daugherty_Lab just now at #KSRNAVirus25 on innate immune sensing of viral proteases If you're interested in reading more, this @PLOSBiology article is part of the work he discussed
Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/TKrkEwiv5v #biorxiv_immuno
Study: "Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome" https://t.co/WS9MoalCiP
Innate immune #CARD8 mechanism for sensing #coronavirus & #picornavirus infection by detecting activity of #virus-encoded proteases; genetic variants in mammalian hosts affect which viruses can be sensed @BriBerryTea @psmitchej @Daugherty_Lab #PLOSBiology https://t.co/YsKMxCR6Rs https://t.co/fTqe98HMOc
This video explores host-specific sensing mechanisms of coronaviruses and picornaviruses by the CARD8 inflammasome. The study reveals significant findings on how the inflammasome responds to viral protease activity…
@scott_scientist @AndrewG76201347 This one is interesting in that it differentiates 3Cpro (includes EV-ME) from 3CLpro (includes LC). https://t.co/jkZeN7gckm
@CovidSolidarit1 @brownecfm @TMaritanoAquino One example: https://t.co/jkZeN7gckm
@AndrewG76201347 @DrScomaME_CFS @GreyKitties One example of EV/picorna vs CoV genetic susceptibility. https://t.co/jkZeN7fEuO
@ishbelfrazer This SNP would be one place for the study to look. "…we find that a single nucleotide polymorphism (SNP) in humans reduces CARD8's ability to sense coronavirus 3CLpros and, instead, enables sensing of 3C proteases (3Cpro) from select picornaviruses." https://t.co/jkZeN7gckm
@DanMissailidis @GrasLab A different topic, but perhaps a transferable concept when looking at ME/MECFS vs LC or different inducing factors within heterogeneous conditions: https://t.co/Iy2TMPCr6d
RT @npariente: Great talk by the @Daugherty_Lab just now at #KSRNAVirus25 on innate immune sensing of viral proteases If you're interested…
RT @npariente: Great talk by the @Daugherty_Lab just now at #KSRNAVirus25 on innate immune sensing of viral proteases If you're interested…
RT @npariente: Great talk by the @Daugherty_Lab just now at #KSRNAVirus25 on innate immune sensing of viral proteases If you're interested…
Great talk by the @Daugherty_Lab just now at #KSRNAVirus25 on innate immune sensing of viral proteases If you're interested in reading more, this @PLOSBiology article is part of the work he discussed
Consistent with this possibility, we found that CARD8 was either lacking in bats, or coronavirus 3CLpros antagonize rather than activate megabat CARD8, reminiscent of prior work demonstrating that bats have a dampened NLRP3 inflammasome response https://t.co/rgOHLSdoJw
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome We demonstrate that CARD8 has the capacity to detect viral proteases from at least 3 viral families that include important human pathogens: Coronaviridae, Picornaviridae, and Retroviridae.
the reason why we dont fight off covid like other diseases is due to genetic flaw in Hominidae. the CARD8 gene. thanks to friesein, it opened a whole new line of research i been starting to read up on! https://t.co/DZo3VYd9lR
@DonEford @Friesein this is the one of the very few ways, that one can elicit the old school hybrid immunity is through T-Cell reprogramming. https://t.co/DZo3VYd9lR
RT @Dakota_150: Study: "Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome" https://t.co/WS9MoalCiP
Study: "Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome" https://t.co/WS9MoalCiP
Host-specific sensing of #coronavirus & #picornavirus by CARD8 #inflammasome Study shows CARD8 is a broad sensor of viral protease activities & suggests CARD8 diversity contributes to inter- & intraspecies variation in inflammasome-mediated viral sensing https://t.co/KRBsf2cNUb
RT @medical_xpress: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M h…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @BWFUND: From @PLOSBiology - Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/Abkzt7YDqP…
From @PLOSBiology - Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/Abkzt7YDqP #bwfpath https://t.co/daSwps2CtY
@G_Commish @ejustin46 @Nk9992Nk @supertodd1 @amcalber @dgurdasani1 @VirusesImmunity @EricTopol @EU_Commission “we find that a single nucleotide polymorphism (SNP) in humans reduces CARD8’s ability to sense coronavirus 3CLpros and, instead, enables sensing of 3C proteases (3Cpro) from select picornaviruses.” https://t.co/tRhubX3UMA
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
Innate immune #CARD8 mechanism for sensing #coronavirus & #picornavirus infection by detecting activity of #virus-encoded proteases; genetic variants in mammalian hosts affect which viruses can be sensed @BriBerryTea @psmitchej @Daugherty_Lab #PLOSBiology https://t.co/YsKMxCREH0 https://t.co/uTNPK49Kcy
Innate immune #CARD8 mechanism for sensing #coronavirus & #picornavirus infection by detecting activity of #virus-encoded proteases; genetic variants in mammalian hosts affect which viruses can be sensed @BriBerryTea @psmitchej @Daugherty_Lab #PLOSBiology https://t.co/YsKMxCR6Rs https://t.co/fTqe98HMOc
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
Innate immune #CARD8 mechanism for sensing #coronavirus & #picornavirus infection by detecting activity of #virus-encoded proteases; genetic variants in mammalian hosts affect which viruses can be sensed @BriBerryTea @psmitchej @Daugherty_Lab #PLOSBiology https://t.co/YsKMxCREH0 https://t.co/ie5Yakf0V4
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/x50i8OWuJM https://t.co/5uGYAeKW2N
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/cw0IsLQQ6w
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/El72jBpQLM
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i…
Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome | PLOS Biology https://t.co/l5jptNDGBq
Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out in @PLOSBiology ! https://t.co/7ro2yhrzVs…Huge congratulations to all involved! More info and thanks to our many collaborators are in the thread below: https://t.co/KIdjQdxO0A
RT @medical_xpress: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M h…
RT @medical_xpress: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M h…
Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M https://t.co/BoHIY2u5RF
RT @medical_xpress: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M h…
Tsu and colleagues show "Host specific sensing of #coronaviruses and #picornaviruses by the CARD8 inflammasome". Thanks for using @vipr_db; you can now access all our data and tools @BVBRC_DB! https://t.co/kBWGD63mqx
New preprint: Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/WjvExkQiKi #coronavirus #COVID19
RT @biorxiv_immuno: Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/TKrkEwiv5v #biorxiv_i…
Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/TKrkEwiv5v #biorxiv_immuno
Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome https://t.co/HLCFRegoZq #bioRxiv