Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery.
Participants express strong interest and moderate engagement by discussing the technical advancements and potential applications of Precious1GPT, using phrases like 'target discovery' and 'aging clock development' to emphasize its scientific and therapeutic relevance. Their tone suggests they see this research as impactful for future aging and medical interventions.
AgreementModerate agreement
Most discussions recognize the significance of Precious1GPT in advancing aging research, indicating general support and agreement with its potential.
InterestHigh interest
The multiple references to the publication and focus on innovative methods show high interest from the community.
EngagementModerate engagement
Participants engage by sharing summaries, reactions, and highlighting key features, reflecting moderate to deep involvement.
ImpactModerate impact
The emphasis on potential for therapeutic discovery and innovation suggests the discussions see a meaningful influence of the work in the field.
Abstract in brief
The study introduces Precious1GPT, a new multimodal aging clock that uses both methylation and transcriptomic data to predict biological age and identify potential therapeutic targets, addressing the limitations of existing aging clocks that are often specialized and disconnected.
Although Precious1GPT's accuracy in predicting age is slightly lower than specialized clocks, it offers greater potential for discovering new therapeutic targets by analyzing features important for aging and age-related diseases, which could lead to interventions that modify biological age.
The researchers also used the PandaOmics platform to annotate and identify promising targets, providing a pathway for drug discovery and validation aimed at reversing or accelerating biological aging.
Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs)
@biogerontology · X
New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery
We developed a multi-modal epigenetic and transcriptomic clock that can be used for target https://t.co/hq9cERhVOC
Jun 15, 2023 · 20 likes · 3 shares · 33,095 followersView post →
PX
Peter Xing
@peterxing · X
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery | Aging https://t.co/uqWGMPYmo8
Jun 16, 2023 · 5 likes · 1 share · 24,518 followersView post →
BC
Biomarkers of Aging Consortium
@agingbiomarkers · X
New paper by Consortium member @biogerontology and colleagues on Precious1GPT, a multimodal transformer-based transfer learning for #aging clock development and feature importance analysis for aging and age-related disease target discovery. https://t.co/wmogCsynJ5
Jun 18, 2023 · 5 likes · 1 share · 2,432 followersView post →
A
Agingdoc
@agingdoc1 · X
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery
Anatoly Urban, @biogerontology & coauthors.
https://t.co/PC5Y1edrfJ @AgingJrnl https://t.co/g8ZIBtqROO
Jun 15, 2023 · 3 likes · 1 share · 43,746 followersView post →
TA
Transhumanism Australia
@transhumanAU · X
RT @peterxing: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for…
Jun 16, 2023 · 1 share · 18,503 followersView post →
KY
Kejun (Albert) Ying
@KejunYing · X
RT @biogerontology: New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature i…
Jun 15, 2023 · 3 shares · 2,248 followersView post →
Introducing Precious1GPT, a multimodal aging clock that combines methylation and transcriptomic data to predict biological age and identify therapeutic targets, enhancing research for age-related disease interventions.
This video discusses Precious1GPT, a multimodal aging clock that combines methylation and transcriptomic data to predict biological age and identify therapeutic targets, offering improvements over existing models for…
New paper by Consortium member @biogerontology and colleagues on Precious1GPT, a multimodal transformer-based transfer learning for #aging clock development and feature importance analysis for aging and age-related disease target discovery. https://t.co/wmogCsynJ5
Jun 18, 2023 · 5 likes · 1 share · 2,432 followersView post →
TA
Transhumanism Australia
@transhumanAU · X
RT @peterxing: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for…
Jun 16, 2023 · 1 share · 18,503 followersView post →
PX
Peter Xing
@peterxing · X
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery | Aging https://t.co/uqWGMPYmo8
Jun 16, 2023 · 5 likes · 1 share · 24,518 followersView post →
AS
Arne Søraas
@ArSoraas · X
RT @biogerontology: New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature i…
Jun 16, 2023 · 3 shares · 257 followersView post →
KY
Kejun (Albert) Ying
@KejunYing · X
RT @biogerontology: New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature i…
Jun 15, 2023 · 3 shares · 2,248 followersView post →
CV
Carles Villaplana
@carlesvillapla1 · X
RT @biogerontology: New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature i…
Jun 15, 2023 · 3 shares · 368 followersView post →
Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs)
@biogerontology · X
New Paper Alert: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery
We developed a multi-modal epigenetic and transcriptomic clock that can be used for target https://t.co/hq9cERhVOC
Jun 15, 2023 · 20 likes · 3 shares · 33,095 followersView post →
JS
J Sam
@JaicSam · X
RT @agingdoc1: Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for…
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery
Anatoly Urban, @biogerontology & coauthors.
https://t.co/PC5Y1edrfJ @AgingJrnl https://t.co/g8ZIBtqROO
Jun 15, 2023 · 3 likes · 1 share · 43,746 followersView post →
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