Gastroenterology September 2023 PMID 37315867

Association of Proton Pump Inhibitor Use With Incident Dementia and Cognitive Decline in Older Adults: A Prospective Cohort Study.

Raaj S Mehta, Bharati Kochar, Zhen Zhou, Jonathan C Broder, Paget Chung, Keming Yang, Jessica Lockery, Michelle Fravel, Joanne Ryan, Suzanne Mahady, Suzanne G Orchard, John J McNeil, Anne Murray, Robyn L Woods, Michael E Ernst

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Mentions

Peak: 24 in Sep 2023

across 4 sources since Jun 2023

Extended reach

108,843

potential audience

Total likes

875

Video views

11,394

Mentions per month

Jun 2023 – Feb 2024

Where it's discussed

X / Twitter31 posts
News27 articles
YouTube2 videos
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AI synopsis

What people are saying

Several discussions explicitly reference the methodology, such as highlighting that this study is prospective and large-scale, which lends credibility to its findings. Language varies from cautious acknowledgment to subtle skepticism, indicating a nuanced engagement with the research's implications and limitations, with phrases like 'most studies find' or 'disappear after validation,' illustrating a blend of interest and critical thinking.

AgreementNeither agree nor disagree

Most discussions recognize the study's findings that PPI use is not significantly linked to dementia risk, reflecting neutral or cautious acceptance because of conflicting past research.

InterestHigh interest

Posts demonstrate high interest by referencing the study’s focus on cognitive health and medication safety, often highlighting the importance of the findings.

EngagementModerate engagement

Many comments engage with the topic by referencing methodologies, previous studies, or the implications for clinical practice, showing at least superficial to moderate involvement.

ImpactNeutral impact

Overall, posts suggest moderate impact—while some see it as confirming or challenging prior beliefs, many recognize its importance but do not dramatically change perspectives or practices.

Abstract in brief

This study examined whether the use of proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs), both medications for reducing stomach acid, are linked to the risk of developing dementia or experiencing cognitive decline in adults aged 65 and older.
The research analyzed data from a large group of nearly 19,000 older adults, carefully reviewing medication use and applying proper diagnostic criteria for dementia, which helped avoid past issues with misclassification.
The findings showed no significant association between the use of PPIs or H2RAs and increased risk of dementia, cognitive impairment, or decline over time, suggesting that these medications are likely safe concerning cognitive health in older adults.

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All mentions

Assessing the Link Between Proton Pump Inhibitors and Dementia in Older Adults

This study examined whether use of proton pump inhibitors and H2 receptor antagonists is linked to dementia risk in adults 65 and older. The findings showed no significant association, suggesting these medications are…

Dr Cleber Santana psiquiatra · Jul 7, 2023 10,787 views

Impact of Common Medications on Memory and Cognitive Health

Discover how everyday medications may affect your memory and cognition. This video explores the scientific evidence, including recent studies showing no significant link between medications like PPIs and cognitive…

Healthy Women Channel · Feb 9, 2024 608 views

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RT @fgomollon: @puentesfabi @docramiro @darosselli Como siempre en este tema (repito, siempre) estudios retrospectivos que encuentran una a…

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RT @fgomollon: @puentesfabi @docramiro @darosselli Como siempre en este tema (repito, siempre) estudios retrospectivos que encuentran una a…

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Association of Proton Pump Inhibitor Use With Incident Dementia and Cognitive Decline in Older Adults: A Prospective Cohort Study - Gastroenterology https://t.co/mNWoheeYXk

Sep 10, 2023 · 1,340 followers View post →

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森　勇一

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元論文は Gastroenterology: ASSOCIATION OF PROTON PUMP INHIBITOR USE WITH INCIDENT DEMENTIA AND COGNITIVE DECLINE IN OLDER ADULTS: A PROSPECTIVE COHORT STUDY https://t.co/xGuSsE19He

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pinacol

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Association of Proton Pump Inhibitor Use With Incident Dementia and Cognitive Decline in Older Adults: A Prospective Cohort Study.

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Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Assessing the Link Between Proton Pump Inhibitors and Dementia in Older Adults

Impact of Common Medications on Memory and Cognitive Health