Exploration (Beijing) August 2022 PMID 37325607

Bioinspired copper single-atom nanozyme as a superoxide dismutase-like antioxidant for sepsis treatment.

Ji Yang, Ruofei Zhang, Hanqing Zhao, Haifeng Qi, Jingyun Li, Jian-Feng Li, Xinyao Zhou, Aiqin Wang, Kelong Fan, Xiyun Yan, Tao Zhang

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Mentions

2
Peak: 1 in Jul 2022
across 2 sources since Jul 2022

Extended reach

233
potential audience

Total likes

6

Video views

51

Mentions per month

Jul 2022 – Aug 2023

Where it's discussed

  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone reflects positive acknowledgment of the research's novelty and potential benefits, with discussions highlighting phrases like 'game-changing approach' and 'promising treatment' which convey enthusiasm. Several posts mention the bioinspired nature of the nanozyme and its role as an antioxidant, emphasizing both scientific innovation and the potential for clinical impact.

AgreementModerate agreement

Most discussions acknowledge the importance and relevance of the research, with some expressing strong support for its potential applications in sepsis treatment.

InterestHigh interest

The high interest score reflects enthusiasm and curiosity about the nanozyme's innovative approach and its implications for medicine.

EngagementModerate engagement

Comments include references to the method and significance of the discovery, indicating moderate depth of engagement.

ImpactModerate impact

While some see the research as promising, the discussions suggest recognition of its potential impact but with some cautious optimism rather than certainty.

Abstract in brief

  • The study discusses a new type of nanozyme called CuSAzyme, inspired by the natural enzyme superoxide dismutase (SOD), designed to fight oxidative stress in sepsis.
  • CuSAzyme mimics natural SOD by efficiently neutralizing superoxide radicals (O2•−), thereby reducing harmful reactive oxygen and nitrogen species (RONS) that cause tissue damage in sepsis.
  • In animal tests, the CuSAzyme was effective in lowering systemic inflammation and preventing damage to multiple organs, showing promise as a potential treatment for sepsis.]

Top posts

Most liked on X and Bluesky
Kelong Fan
@fankelong · X

Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment https://t.co/EPtAV0euMU #nanozyme#SOD#Sepsis#SAzyme

Jul 13, 2022 · 4 likes · 182 followers View post →

All mentions

Kelong Fan
@fankelong · X

Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment https://t.co/EPtAV0euMU #nanozyme#SOD#Sepsis#SAzyme

Jul 13, 2022 · 4 likes · 182 followers View post →