Synopsis of Social media discussions
Many discussions highlight the alarming findings that social isolation and loneliness substantially raise the risk of mortality, with users reflecting on the data by stating, 'This meta-analysis reveals critical links between social disconnection and health outcomes.' The tone is urgent and serious, especially when phrases like 'we must take action' and 'this is a wake-up call' are used, which contribute to the overall sentiment of concern and proactive intent surrounding the article.
Agreement
Strong agreementThe discussions overwhelmingly support the findings of the publication, emphasizing the importance of addressing social isolation and loneliness.
Interest
High level of interestThere is high curiosity evident in the posts, with many users expressing eagerness to learn more about the implications of the research.
Engagement
High engagementSeveral posts delve into the research's methodologies and findings, showcasing a deep understanding of the topic and encouraging further conversation.
Impact
High level of impactUsers perceive this study as having significant implications for public health and mental health interventions, with many echoing calls for increased awareness and action.
Social Mentions
YouTube
2 Videos
Bluesky
100 Posts
3 Posts
73 Posts
Blogs
15 Articles
News
234 Articles
5 Posts
Metrics
Video Views
1,212
Total Likes
450
Extended Reach
954,531
Social Features
432
Timeline: Posts about article
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Journal of Studies on Alcohol and Drugs
@jsadjournal.bsky.social (Bluesky)Cannabis Vaping in Youth: A Systematic Review and Meta-Analysis of Risk Factors in Adolescents and Young Adults (just accepted in @jsadjournal.bsky.social) @garyckchan.bsky.social @cretobacco.bsky.social @griffith.edu.au @ncysur.bsky.social www.jsad.com/doi/abs/10.1...
view full postAugust 8, 2025
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@arxivlens.bsky.social (Bluesky)Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators Kördel, M., Kroemer, N. B. et al. Paper Details
view full postAugust 7, 2025
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Éric Maeker
@dr.maeker.fr (Bluesky)August 7, 2025
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medRxivpreprint
@medrxivpreprint.bsky.social (Bluesky)Regorafenib in Bone Sarcoma: A Systematic Review and Meta-Analysis of Its Effectiveness and Safety in Cancer Treatment https://www.medrxiv.org/content/10.1101/2025.08.04.25332569v1
view full postAugust 6, 2025
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Madeleine Kördel
@mkoerdel.bsky.social (Bluesky)August 6, 2025
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bioRxiv Physiology
@biorxiv-physio.bsky.social (Bluesky)Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators https://www.biorxiv.org/content/10.1101/2025.08.05.668684v1
view full postAugust 6, 2025
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bioRxivpreprint
@biorxivpreprint.bsky.social (Bluesky)Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators https://www.biorxiv.org/content/10.1101/2025.08.05.668684v1
view full postAugust 6, 2025
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EdArXivBot
@edarxiv.bsky.social (Bluesky)A Systematic Review and Meta-Analysis of CW-FIT: https://osf.io/vdb3y
view full postAugust 4, 2025
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Éric Maeker
@dr.maeker.fr (Bluesky)Association between social integration and risk of dementia: A systematic review and meta-analysis of longitudinal studies. J Am Geriatr Soc 2023 2/7
view full postAugust 2, 2025
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JAACAP Journals
@jaacapjournals.bsky.social (Bluesky)Noninvasive Brain Stimulation in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Treatment Efficacy and Targeting Strategies #jaacap #articleinpress https://twp.ai/4ipgSh
view full postJuly 29, 2025
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Elena Shekhova, PhD
@lumipie.com (Bluesky)July 27, 2025
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Klebsiella Papers
@klebpapers.bsky.social (Bluesky)Prevalence of Antimicrobial Resistance in Klebsiella pneumoniae in the South African Populations: A Systematic Review and Meta-Analysis of Surveillance Studies https://doi.org/doi:10.1002/mbo3.70037
view full postJuly 25, 2025
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kinetoplastids papers
@kinetoplastpapers.bsky.social (Bluesky)Inspiratory muscle training for chronic critically ill patients: a systematic review and meta-analysis of randomized controlled trials pubmed.ncbi.nlm.nih.gov/40699051/
view full postJuly 24, 2025
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MaskTogetherAmerica
@togetherwemask.bsky.social (Bluesky)20% of #LongCOVID patients continue to struggle with one or more lingering symptoms after 3 yrs
view full postJuly 23, 2025
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Open Forum Infectious Diseases
@ofidjournal.bsky.social (Bluesky)The impact of point-of-care testing for Group A streptococcal pharyngitis on antibiotic prescribing and patient health outcomes in outpatient care: a systematic review and meta-analysis of randomized controlled trials ✅ Just Accepted #IDSky
view full postJuly 22, 2025
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@utkablooger.bsky.social (Bluesky)Cardiac adverse events associated with remdesivir in COVID-19 patients: a systematic review and meta-analysis of randomised controlled trials Introduction Remdesivir (GS-5734) was the first antiviral drug approved by the United States Food and Drug Administration (FDA) to be used as a treatment…
view full postJuly 21, 2025
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JMIR Publications
@jmirpub.bsky.social (Bluesky)Reminder>> Biting into #Digital solutions: A systematic review and meta-analysis of #Digital interventions targeting healthy and sustainable eating behavior (preprint) #openscience #PeerReviewMe #PlanP
view full postJuly 21, 2025
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Muhammed A Moukhtar Hammad
@mo-moukhtar.bsky.social (Bluesky)Grateful to be part of this important work published in @urogoldjournal.bsky.social ! Robotic-Assisted vs. Open Kidney Transplantation: A Systematic Review and Meta-Analysis of Propensity-Matched Studies www.goldjournal.net/article/S009... @elsfoundation.bsky.social @elsevierconnect.bsky.social
view full postJuly 20, 2025
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JMIR Publications
@jmirpub.bsky.social (Bluesky)Biting into #Digital solutions: A systematic review and meta-analysis of #Digital interventions targeting healthy and sustainable eating behavior (preprint) #openscience #PeerReviewMe #PlanP
view full postJuly 18, 2025
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Francisco Câmara Ferreira
@fcamaraferreira.bsky.social (Bluesky)Effect of Plant Versus Animal Protein on Muscle Mass, Strength, Physical Performance, and Sarcopenia: A Systematic Review and Meta-analysis of Randomized Controlled Trials url: academic.oup.com/nutritionrev...
view full postJuly 15, 2025
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Bruno Santos
@brunoksak (Twitter)Solidão dói — e mata: meta-análise com 2 M de adultos mostrou +30 % de risco de morte em isolados. Conecte-se hoje. #SaúdeMental #Longevidade https://t.co/BcqIPwKaLm
view full postMay 26, 2025
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Loneliness & SI in Mental Health research network
@UCL_Loneliness (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postDecember 22, 2024
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Jiwon Park
@JlWON_PARK_ (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postDecember 16, 2024
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Leonhard Schilbach
@leoschilbach (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postDecember 16, 2024
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CopperKettle
@Artyom_Yekat (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postDecember 15, 2024
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Leonhard Schilbach
@leoschilbach (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/9rS8euloor
view full postDecember 15, 2024
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Aneeque Javaid
@Raneeque (Twitter)RT @I4Replication: Last DP of the week is by Molo et al. They conduct sensitivity analysis and computationally reproduce "A Systematic Revi…
view full postOctober 25, 2024
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I4R
@I4Replication (Twitter)Last DP of the week is by Molo et al. They conduct sensitivity analysis and computationally reproduce "A Systematic Review and Meta-Analysis of 90 Cohort Studies of Social Isolation, Loneliness and Mortality" @NatureHumBehav by Wang et al. Full report and authors' response below https://t.co/2Us6WGs9EN
view full postOctober 25, 2024
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thmonk
@thmonk_pf (Twitter)RT @leafs_s_jp: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/9bH7t…
view full postApril 19, 2024
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leafs
@leafs_s_jp (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/9bH7teFsZT
view full postApril 19, 2024
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Prakash Masand
@PMasand (Twitter)A systematic review and meta-analysis of 90 cohort studies of social #isolation, #loneliness and mortality.Both social isolation and loneliness were significantly associated with an increased risk of all-cause mortality. https://t.co/Kr2IWhZuGA #nursepractitioner #mentalhealth
view full postAugust 7, 2023
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塩川宏郷
@ddtsubucafe (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/LtdWNT7Fi9
view full postJuly 24, 2023
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Boussageon Rémy
@BoussageonR (Twitter)RT @pash22: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/GBpvIAVY3…
view full postJuly 18, 2023
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Saber C. Saharkhiz
@SaharkhizSaber (Twitter)RT @NeuroscienceNew: “A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality” by Fan Wang…
view full postJuly 18, 2023
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Ash Paul
@pash22 (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/GBpvIAVY3o https://t.co/AlV3ZSJEyQ
view full postJuly 18, 2023
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理学療法士_海津陽一 Ph.D.
@copellist (Twitter)■ Ref info: Wang et al. Nature Human Behaviour (2023): 1-13. ■ Ref link: https://t.co/PC3zsgcQNv ■ ハイライト(
view full postJuly 16, 2023
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HealthyBuilds
@HealthyBuilds (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/VeZmBnfpPi
view full postJuly 12, 2023
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Psicólogo Celestino González-Fernández ψ
@Tecnoestres (Twitter)A systematic review and meta-analysis of 90 cohort studies of social #isolation, loneliness and mortality @nature #CGFPsicología https://t.co/5Ogopqv7D7
view full postJuly 6, 2023
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Real_Dr_Roy
@real_dr_roy (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/pXA22GcxI7
view full postJune 28, 2023
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Julian Mutz
@julianmutz (Twitter)RT @agingdoc1: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality
view full postJune 26, 2023
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Ex_Citizen_BuckTweet
@GuyGadboisGuyG1 (Twitter)RT @agingdoc1: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality
view full postJune 26, 2023
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Agingdoc
@agingdoc1 (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality
view full postJune 26, 2023
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Dr Anthony Martin
@AMAinsight (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/ZQIErf8jx2
view full postJune 26, 2023
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LogopsychisInstitute
@logopsychis (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 25, 2023
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Manuel Pérez-Alonso, PhD
@MPAlonso (Twitter)RT @MPAlonso: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behav…
view full postJune 23, 2023
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Manuel Pérez-Alonso, PhD
@MPAlonso (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/01j2FsUCiX
view full postJune 22, 2023
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Gadi Gilam גדי גילעם جدي جيلام
@gadigilam (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 22, 2023
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Juan
@juanpabloz87 (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 22, 2023
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McLight
@Jameslight96 (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Mohamed Elsayed, MD
@Elsayed8743 (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Patrick Lockwood
@DoctorLockwood (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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MO
@Ma18238890 (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Ziqian Xia
@Ziqian_Xia (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Meng-Chuan Lai 賴孟泉
@mengchuanlai (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Anne Booyse
@Annemarylinb (Twitter)RT @NeuroscienceNew: “A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality” by Fan Wang…
view full postJune 21, 2023
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Sander Koole
@SLKoole (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Venezuela en el Alma
@carmendalvano3 (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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Rosaura Brisuela @roswitta.bsky.social
@Roswitamind (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 21, 2023
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opc kdn(鷦鷯飛蝗∈猩々飛蝗)
@KdnOpc (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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priya joseph
@ayirpelle (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 20, 2023
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荒井弘和
@hirokazuarai (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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William L. Smith
@Psychgallica (Twitter)RT @sminaev2015: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Be…
view full postJune 20, 2023
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zaregoto_chi
@kaichi_chi (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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h
@_h_japan (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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Claudia_La
@ClLazarides (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 20, 2023
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Jose Chavez Martinez
@matracaelcan (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 20, 2023
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Neagu Cosmin
@NeaguCosminA (Twitter)RT @NeuroscienceNew: “A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality” by Fan Wang…
view full postJune 20, 2023
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Paul Nightingale
@Nightingale_P (Twitter)RT @pash22: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/GBpvIAVY3…
view full postJune 20, 2023
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Neuroscience News
@NeuroscienceNew (Twitter)“A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality” by Fan Wang et al. Nature Human Behavior https://t.co/NG6S0ksKKA 3/3
view full postJune 20, 2023
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Dr Andrew Furber
@FurberA (Twitter)RT @pash22: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/GBpvIAVY3…
view full postJune 20, 2023
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Ash Paul
@pash22 (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/GBpvIAVY3o https://t.co/AYjX1H0l42
view full postJune 20, 2023
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Sky Health, LLC
@GotSkyHealth (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality #isolation #SocialIsolation #loneliness #mortality #MentalHealth #health #depression #anxiety https://t.co/H5rbJKm4V3
view full postJune 20, 2023
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Marcelo Demarzo
@DemarzoMarcelo (Twitter)RT @sminaev2015: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Be…
view full postJune 20, 2023
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Leonhard Schilbach
@leoschilbach (Twitter)RT @leoschilbach: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human B…
view full postJune 20, 2023
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A good person
@Seenthem (Twitter)RT @sminaev2015: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Be…
view full postJune 20, 2023
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Leonhard Schilbach
@leoschilbach (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/9rS8euloor
view full postJune 20, 2023
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いっちー@バーチャル精神科医
@ichiipsy (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality. Nat Hum Behav (2023). https://t.co/eUCzwWogAW
view full postJune 20, 2023
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町田大輔/Daisuke Machida
@DMchida (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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佐藤ポプ
@satopop2011 (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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Sergey Minaev
@sminaev2015 (Twitter)RT @sminaev2015: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Be…
view full postJune 20, 2023
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mammy999
@dddvdgaarunara (Twitter)RT @myuuko: 社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort…
view full postJune 20, 2023
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Yuuko Morimoto
@myuuko (Twitter)社会的孤立・孤独と死亡率の論文はこれかな。社会的に孤立していると,全死因,心血管疾患,がんによる死亡リスクが高くなる。孤独の方がオッズ比は低いっぽい。/ A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/ggUKCrMkba
view full postJune 20, 2023
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NetScience
@net_science (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality https://t.co/ff8JWNAGwl
view full postJune 20, 2023
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preciso.com sa de cv
@preciso_com (Twitter)RT @sminaev2015: A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Be…
view full postJune 20, 2023
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Sergey Minaev
@sminaev2015 (Twitter)A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/4LDjzDrNST
view full postJune 20, 2023
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Carlos Andrés Celis-Preciado
@pulmonology101 (Twitter)RT @AldrinAU: A systematic review and meta-analysis of 90 cohort studies found in the general population, both social isolation & lonelines…
view full postJune 19, 2023
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A.
@AldrinAU (Twitter)A systematic review and meta-analysis of 90 cohort studies found in the general population, both social isolation & loneliness were significantly associated with an increased risk of all-cause mortality @Nature Human Behaviour https://t.co/Tbw4TPQlF1
view full postJune 19, 2023
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Chao Wang
@excel_wang (Twitter)Social isolation & loneliness are associated with higher all-cause mortality. A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality | Nature Human Behaviour https://t.co/Rrv5eCWm8S
view full postJune 19, 2023
Abstract Synopsis
- A systematic review analyzed 90 cohort studies involving over 2.2 million adults to understand the impact of social isolation and loneliness on mortality rates.
- Both social isolation and loneliness were found to significantly increase the risk of all-cause mortality, as well as specifically for cancer and cardiovascular disease (CVD).
- The findings suggest that addressing social isolation could be important for improving health outcomes and overall well-being.
Bertoglio lab (FMC/UFSC)
@bertogliolab.bsky.social (Bluesky)