Int J Oral Sci June 2023 PMID 37380627

Oral pathogen aggravates atherosclerosis by inducing smooth muscle cell apoptosis and repressing macrophage efferocytosis.

Hanyu Xie, Ziyue Qin, Ziji Ling, Xiao Ge, Hang Zhang, Shuyu Guo, Laikui Liu, Kai Zheng, Hongbing Jiang, Rongyao Xu

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Mentions

Peak: 2 in Jul 2023

across 2 sources since Jul 2023

Extended reach

148

potential audience

Total likes

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Mentions per month

Jul 2023 – Oct 2023

Where it's discussed

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YouTube1 videos

AI synopsis

What people are saying

The discussions show enthusiasm for the research's potential, with posts describing it as a 'groundbreaking' approach using innovative methods like macrophage membranes for dual treatment. Words such as 'suggests' and hashtags like '#CardiovascularResearch' convey excitement and a sense of significance, emphasizing the study's promising implications for future medical treatments.

AgreementStrong agreement

The discussion strongly supports the significance of the research, highlighting its potential for innovative treatments and emphasizing its importance.

InterestHigh interest

Posts express high curiosity about developing new dual therapies and understanding how oral bacteria influence cardiovascular health.

EngagementModerate engagement

While most discussions are positive and highlight potential applications, there is limited deep technical analysis, indicating moderate engagement.

ImpactHigh impact

The posts suggest that this research could have a transformative impact on treating both periodontal disease and atherosclerosis, reflecting a high perceived importance.

Abstract in brief

Periodontitis may increase the risk of heart diseases due to the oral bacteria P. gingivalis inducing apoptosis and affecting immune responses.
Research reveals that smooth muscle cells (SMCs) are more prone to P. gingivalis-induced cell death through TLR2 activation, leading to a buildup of apoptotic cells.
The study proposes a new treatment using macrophage membranes to deliver medication enhanced by recognizing the effects of P. gingivalis, potentially addressing both atherosclerosis and periodontitis.

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All mentions

Oral Pathogen's Role in Atherosclerosis and Cell Death Mechanisms

Oral pathogens like P. gingivalis can exacerbate atherosclerosis by inducing smooth muscle cell apoptosis and impairing macrophage efferocytosis, highlighting potential treatment strategies targeting immune responses.

Medicine RTCL TV · Oct 15, 2023 20 views

TranSpread

@transpread · X

RT @IJOS_Office: A groundbreaking study in #IJOS suggests a new dual treatment for periodontitis and atherosclerosis using P. gingivalis-pr…

Jul 25, 2023 · 1 share · 61 followers View post →

IJOS_Editorial Office

@IJOS_Office · X

Jul 25, 2023 · 2 likes · 1 share · 64 followers View post →