BMC Public Health June 2023 PMID 37380964

L-shaped association of serum 25-hydroxyvitamin D with all-cause and cardiovascular mortality in older people with chronic kidney disease: results from the NHANES database prospective cohort study.

Rugang Li, Yang Li, Zhongcheng Fan, Zhaoqi Liu, Juhua Lin, Min He

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Mentions

Peak: 2 in Jun 2023

across 2 sources since Jun 2023

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19,773

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Jun 2023 – Oct 2023

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AI synopsis

What people are saying

Several discussions point out the threshold level of 90 nmol/L for vitamin D, with terms like 'significant' and 'predictive' emphasizing importance. Participants express interest in the study’s implications for treatment, and the tone suggests a meaningful engagement with the research findings, reflecting recognition of potential impacts on health management.

AgreementModerate agreement

Most discussions agree that the study highlights a significant relationship between vitamin D levels and mortality risk, especially in CKD patients.

InterestModerate interest

Participants show moderate interest, referencing specific findings like the importance of reaching 90 nmol/L and the thresholds involved.

EngagementModerate engagement

Comments delve into methodological details and implications, indicating thoughtful engagement with the research.

ImpactModerate impact

The discussions recognize potential clinical influence, hinting at implications for managing vitamin D in CKD patients.

Abstract in brief

The study found that in older people with chronic kidney disease, there is an L-shaped relationship between vitamin D levels (serum 25OHD) and mortality, where higher levels up to about 90 nmol/L are linked to lower risks of death from all causes and cardiovascular issues.
Increasing vitamin D levels above 90 nmol/L did not significantly further reduce mortality risk, indicating a threshold effect.
Participants with vitamin D deficiency or insufficiency had higher risks of mortality, and improving vitamin D to sufficient levels was associated with notable decreases in both all-cause and cardiovascular deaths.

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All mentions

Vitamin D Levels and Mortality Risk in Older Chronic Kidney Disease Patients

In older patients with chronic kidney disease, an L-shaped relationship exists between serum 25-hydroxyvitamin D levels and mortality risk. Improving vitamin D to sufficient levels reduces death risks, with a threshold…

Medicine RTCL TV · Oct 17, 2023 27 views

Takuya Kishi @ねこ好き循環器内科医

@tkishi_cardiol · X

Jun 29, 2023 · 1 share · 14,824 followers View post →

宇津貴史 /Utsu, Takashi

@Office_j · X

Jun 29, 2023 · 14 likes · 1 share · 4,918 followers View post →