Systematic review of exosome treatment in hair restoration: Preliminary evidence, safety, and future directions.

Abstract in brief

• Exosomes are tiny vesicles that can influence hair growth and are being explored as a new treatment for alopecia, with recent research showing promising results in both lab and clinical studies.
• A systematic review identified 16 studies, mostly preclinical, which demonstrate that exosomes derived from adipose stem cells and dermal papilla cells can improve hair density and thickness, with minimal reported side effects.
• Despite limited clinical evidence so far, exosome therapy shows potential for hair restoration, but more research is needed to understand how it works, optimize treatment methods, and ensure safety.