Drug Des Devel Ther July 2023 PMID 37397787

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes.

Siddhartha Dutta, Rima B Shah, Shubha Singhal, Sudeshna Banerjee Dutta, Sumit Bansal, Susmita Sinha, Mainul Haque

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Mentions

Peak: 5 in Jul 2023

across 3 sources since Jun 2023

Extended reach

176,988

potential audience

Total likes

10,245

Video views

160,277

Mentions per month

Jun 2023 – Sep 2025

Where it's discussed

X / Twitter10 posts
YouTube2 videos
News2 articles

AI synopsis

What people are saying

Discussions reflect a general consensus that metformin's therapeutic utility extends beyond diabetes, with phrases like 'potential mechanism' and 'therapeutic utility' emphasizing ongoing exploration. The tone suggests cautious optimism, mainly highlighting possibilities without extensive critique, which demonstrates moderate interest and engagement but acknowledgment of their potential significance.

AgreementModerate agreement

Most discussions acknowledge the significance of metformin's potential beyond diabetes, indicating broad agreement on its promising therapeutic benefits.

InterestModerate interest

Participants show some interest in the topic, with mentions of multiple benefits such as anticancer and neuroprotective effects, suggesting curiosity but not deep enthusiasm.

EngagementNeutral engagement

Responses are somewhat superficial, primarily referencing the publication without extensive analysis or critique of mechanisms, showing moderate engagement.

ImpactModerate impact

There is a recognition that this research could influence future treatments, but the overall impact perception remains moderate as they mainly review potentialities rather than definitive breakthroughs.

Abstract in brief

Metformin is a key first-line treatment for type 2 diabetes, primarily working as an antihyperglycemic agent by activating AMPK and reducing liver glucose output.
It has additional benefits, including lowering cardiovascular risks, decreasing harmful substances in the body, and potentially having anticancer and neuroprotective effects against diseases like Alzheimer's and Parkinson's.
The exact mechanisms behind these various effects are not fully understood, but research highlights metformin's promise in treating a wide range of health issues, including obesity, cancer, and metabolic disorders.

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Can Metformin Be Used for Weight Loss Without Diabetes?

This video explores whether metformin, originally developed for type 2 diabetes, can be used for weight loss and other health benefits. It discusses research on its effects on aging, inflammation, and potential uses…

Nunca vi 1 cientista · Sep 12, 2024 160,106 views

Metformin and Glifage: Effects on Weight Loss and Longevity

This video explains the origin, composition, mechanisms, and scientific evidence behind Metformin and Glifage in weight loss and longevity, discussing classic studies, myths, risks, and who can benefit from these…

Dra. Sheyla Alonso · Sep 3, 2025 171 views

Isabel Margarita

@isakine · X

Sep 25, 2025 · 98 followers View post →

Aaron Boster MD

@AaronBosterMD · X

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes - PubMed https://t.co/wncmDZzScW

Jul 5, 2023 · 9 likes · 13,116 followers View post →

Vladimir Villoslada Terrones

@Villoslada_INEN · X

RT @GynOnc_Papers: Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes https://t.co/jvpaCWOBp9

Jul 3, 2023 · 1 share · 547 followers View post →

Mainul Haque

@runurono · X

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes

Jul 3, 2023 · 31 followers View post →

Mainul Haque

@runurono · X

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes https://t.co/SciO3LWYny

Jul 3, 2023 · 31 followers View post →

GynOnc_Papers

@GynOnc_Papers · X

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes https://t.co/jvpaCWOBp9

Jul 3, 2023 · 1 share · 246 followers View post →

Stigmabase | UNITWO

@StigmabaseU · X

Jun 27, 2023 · 2,577 followers View post →

Susmita Sinha

@Susmita07796969 · X

Metformin: potential mechanism & therapeutic utility review | DDDT @DovePress https://t.co/RdwFdBsTCy

Jun 25, 2023 View post →

Mainul Haque

@runurono · X

https://t.co/PFAB6Cr7PD https://t.co/lFv5ESdec1

Jun 25, 2023 · 31 followers View post →

Mainul Haque

@runurono · X

Metformin: potential mechanism & therapeutic utility review | DDDT @DovePress https://t.co/UZt7Eq8lyq

Jun 25, 2023 · 31 followers View post →

Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Can Metformin Be Used for Weight Loss Without Diabetes?

Metformin and Glifage: Effects on Weight Loss and Longevity