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J Transl Med July 2023 PMID 37408028

A systematic review and meta-analysis of urinary biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Asher Taccori, Rebekah Maksoud, Natalie Eaton-Fitch, Maharshi Patel, Sonya Marshall-Gradisnik

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Mentions

26
Peak: 18 in Jul 2023
across 5 sources since Jul 2023

Extended reach

66,874
potential audience

Total likes

77

Video views

18

Mentions per month

Jul 2023 – Oct 2023

Where it's discussed

  • X / Twitter19 posts
  • Facebook2 posts
  • Reddit2 posts
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

Many responses, such as the comment about ‘comparing apples and oranges,’ reflect skepticism about the study's approach and highlight ongoing debates on the biological differences within ME/CFS subtypes. The tone varies from dismissive to mildly inquisitive, showing that the publication sparked interest but also criticism for its methodology and interpretations.

AgreementLow agreement

Most discussions express skepticism or highlight methodological issues, indicating disagreement with the study's utility or validity.

InterestModerate interest

Participants show moderate interest, mainly engaging due to relevance to ongoing debates and research, rather than enthusiasm.

EngagementNeutral engagement

Engagement appears superficial, with some users repeating comments or sharing links without deep analysis.

ImpactNeutral impact

The discussions suggest a neutral impact, with some users questioning the significance or generalizability of the findings.

Abstract in brief

  • This systematic review and meta-analysis examined urinary biomarkers in MECFS, a complex illness affecting multiple body systems, to identify potential diagnostic markers by analyzing 21 studies comparing MECFS patients with healthy controls.
  • The review focused on various urinary markers, such as free cortisol, carnitine, iodine, and the metabolome, revealing some differences in these measures between MECFS patients and healthy individuals, although findings varied across studies.
  • Using standardized quality assessments and a meta-analysis approach, the study aimed to synthesize existing evidence to support the development of noninvasive diagnostic tools for MECFS, highlighting the current gaps and variability in urinary biomarker research.
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Top posts

Most liked on X and Bluesky
Herbert Renz-Polster
@RenzPolster · X

Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiology of #MECFS differs completely between PEM ond non-PEM days - just analysing random samples is just a waste of time. https://t.co/RTTG0dytwe

Jul 8, 2023 · 59 likes · 11 shares · 8,585 followers View post →
Tom Kindlon
@TomKindlon · X

New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #ChronicFatigueSyndrome (ME/CFS)" Free full text: https://t.co/23hrLoGhOB #MEcfs #CFS #MyalgicE #PwME https://t.co/dTGF2KW5Be

Jul 6, 2023 · 11 likes · 4 shares · 15,121 followers View post →
Science for ME online forum
@s4me_info · X

A systematic review and meta-analysis of urinary biomarkers in (ME/CFS) - Taccori et al https://t.co/N0WIpgXFwP 4/7

Jul 10, 2023 · 5 likes · 5,519 followers View post →
Millions Missing France
@MillionsMissgFr · X

2. Biomarqueurs urinaires: A systematic review and meta-analysis of urinary biomarkers in ME/CFS (07/23) https://t.co/LihJVoaEeB 3. Micro-ARN : Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (06/ 2023) https://t.co/5fegG4fVNK 2/8

Sep 16, 2023 · 1 like · 2,168 followers View post →
ME/CFS Research
@cfs_research · X

A systematic review and meta-analysis of urinary biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) https://t.co/Y57zN5BhS8

Jul 6, 2023 · 1 like · 1,183 followers View post →
Billy Hanlon
@bhanlon15 · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 11, 2023 · 11 shares · 13,623 followers View post →

All mentions

Millions Missing France
@MillionsMissgFr · X

2. Biomarqueurs urinaires: A systematic review and meta-analysis of urinary biomarkers in ME/CFS (07/23) https://t.co/LihJVoaEeB 3. Micro-ARN : Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (06/ 2023) https://t.co/5fegG4fVNK 2/8

Sep 16, 2023 · 1 like · 2,168 followers View post →
Billy Hanlon
@bhanlon15 · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 11, 2023 · 11 shares · 13,623 followers View post →
Science for ME online forum
@s4me_info · X

A systematic review and meta-analysis of urinary biomarkers in (ME/CFS) - Taccori et al https://t.co/N0WIpgXFwP 4/7

Jul 10, 2023 · 5 likes · 5,519 followers View post →
Margita Kleye
@KleyeMargita · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 9, 2023 · 11 shares · 197 followers View post →
John Muir @johnmuir@aus.social
@johnamuir · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 9, 2023 · 11 shares · 1,160 followers View post →
Brain Drain
@braindrain21 · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 400 followers View post →
Kirsten Röder
@kirsten_roder · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 830 followers View post →
⭕️MECFS/LC⭕️Eine kämpfende Mama⭕️
@Arizona10238417 · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 1,519 followers View post →
Mööp
@Meoeop · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 268 followers View post →
꧁❁⭒
@Violettatamm · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 1,689 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 8,758 followers View post →
Frau_Zebra
@frau_zebra · X

RT @RenzPolster: Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiolo…

Jul 8, 2023 · 11 shares · 371 followers View post →
Herbert Renz-Polster
@RenzPolster · X

Again, there is really no point in doing such reviews as long as we continue to compare apples and oranges. The pathobiology of #MECFS differs completely between PEM ond non-PEM days - just analysing random samples is just a waste of time. https://t.co/RTTG0dytwe

Jul 8, 2023 · 59 likes · 11 shares · 8,585 followers View post →
Susan Fairlie Hall
@FairlieHall · X

RT @TomKindlon: New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #C…

Jul 7, 2023 · 4 shares · 1,395 followers View post →
SÍNDROME DA FADIGA CRÔNICA USE PFF2!
@sfadigacronica · X

RT @TomKindlon: New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #C…

Jul 6, 2023 · 4 shares · 779 followers View post →
ME/CFS Research
@cfs_research · X

A systematic review and meta-analysis of urinary biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) https://t.co/Y57zN5BhS8

Jul 6, 2023 · 1 like · 1,183 followers View post →
nanniJu
@bullfinch921 · X

RT @TomKindlon: New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #C…

Jul 6, 2023 · 4 shares · 440 followers View post →
Irish ME/CFS Association
@IrishMECFSAssoc · X

RT @TomKindlon: New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #C…

Jul 6, 2023 · 4 shares · 2,569 followers View post →
Tom Kindlon
@TomKindlon · X

New from NCNED (Australia): A systematic review and meta-analysis of urinary biomarkers in #MyalgicEncephalomyelitis / #ChronicFatigueSyndrome (ME/CFS)" Free full text: https://t.co/23hrLoGhOB #MEcfs #CFS #MyalgicE #PwME https://t.co/dTGF2KW5Be

Jul 6, 2023 · 11 likes · 4 shares · 15,121 followers View post →